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Articles by Mohammad A. Alzohairy
Total Records ( 4 ) for Mohammad A. Alzohairy
  Amjad Ali Khan , Mohammad A. Alzohairy and Abdelmarouf H. Mohieldein
  This study was conducted to analyse the possible antidiabetic effects of camel milk in streptozotocin (STZ)-induced diabetic rats by assaying liver and kidney clinical function parameters. Administration of streptozotocin (55 mg kg-1 b.wt.) to the experimental groups of rats resulted in marked detectable changes. The rats were fed daily with fresh camel milk by feeding bottles for 30 days. The effects of camel milk on blood glucose, serum proteins, urea, uric acid, creatinine, lipid profile and the activities of diagnostic marker enzymes of liver function and Alkaline Phosphatase (ALP) were examined in the plasma/serum of control and experimental groups of rats. Camel milk feeding to diabetic rats significantly reduces the levels of blood glucose, urea, uric acid and creatinine and increases the activities of albumin, albumin/globulin ratio and restores all liver function marker enzymes and lipid profile to near control levels. The present study shows that feeding of camel milk to diabetic rats has antihyperglycemic effects and consequently may alleviate liver and renal damage associated with streptozotocin-induced diabetic rats.
  Amjad Ali Khan and Mohammad A. Alzohairy
  Camel milk has been widely used in a number of countries as a food additive and for curing some commonly occurring diseases. Recently, camel milk has been deeply studied for its special properties because of higher hepatoprotective, insulin like and antibacterial activities. These properties distinguish camel milk from milk of other animals. The present study was carried out to investigate the protective effects of camel milk against CCl4-induced hepatotoxicity which lead to biochemical alterations in liver function of male albino wister rats. White albino male rats (200-250 g) were divided into 5 groups, a normal control water group, a control camel milk group and three CCl4-intoxicated groups treated with or without camel milk. Protective roles of camel milk were analyzed by assaying the liver function parameters as serum aminotransferases, alkaline phosphatase, serum proteins and cholesterol levels. Histopathological examinations were also studied in all groups of rats by microscopy. Data showed that intraperitoneal administration of CCl4 (1 mL kg-1 b.wt.) resulted in statistically significant increase in the serum levels of aminotransferases and change in serum protein, albumin and cholesterol levels which approach to normal levels after the treatment with raw camel milk. Furthermore, histopathological studies reveal that camel milk treatments significantly reduce the incidence of liver lesions induced by CCl4. Our findings demonstrate that CCl4 exposure alters liver function biochemical parameters, which shift towards normal values after treatment with camel milk. So camel milk has a good potent for curing some liver diseases.
  Amjad Ali Khan and Mohammad A. Alzohairy
  Immobilized enzymes have been widely used in the processing of variety of products. New strategies are continuously emerging for the formation of diverse immobilized enzymes having superior efficiency and usage. Immobilized enzymes have biomedical and industrial applications and for this reason, this area has continued to develop into an ever-expanding and multidisciplinary field during the last couple of decades. This study is a review of the latest literatures on different enzymes immobilized on various supporting materials. Immobilized enzymes for multiplicity of applications ranging from wine, sugar and fish industry through organic compounds removal from wastewaters to sophisticated biosensors for both in situ measurements of environmental pollutants and metabolite control are reviewed. Generally speaking, immobilized enzymes have immense potential in the analysis of clinical, industrial and environmental samples. Immobilized enzymes and proteins have been tremendously used in antibiotic production, drug metabolism, food industry, biodiesel production and bioremediation. The success of the vast usage of immobilized enzymes lies in the fact that they prove to be environmental friendly, cheaper and easy to use when compared to other parallel technologies.
  Mohammad A. Alzohairy
  Despite the wealth information that have been gathered about Mycobacterium tuberculosis over many decades of research and the availability of live attenuated vaccine, tuberculosis remains to be an expanding global health crisis. Understanding Tuberculosis (TB) epidemiology among certain population is essential for the management of overall TB health program. Thus, the present study was carried out to describe the epidemiology of TB among migrant workers in Qassim region, Saudi Arabia. The 165 migrant patients from the neighboring countries majority from South East Asia accessing the TB services at Regional TB center at Qassim were included in this study. The majority of subjects 72 (43.6%) were from Indonesia and India 38 (23%) followed by Nepal 12 (7.2%). Out of 165 patients, 95 (57.6%) were female compared to 70 (42.4%) males with housemaid being the highest (44.8%) with regard to occupational category. Majority of the cases were of middle age and low socio economic status. Fever, loss of appetite, loss of weight and cough were the chief clinical presentations. Among the total cases, 9 cases (5.4%) were suffering from Diabetes. Over all, Prevalence of TB among migrant is relatively high. Preventive measures for early diagnosis should be performed especially in migrant worker from high-prevalence countries.
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