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Articles by Mohamed Ezzat Abd El-Hack
Total Records ( 5 ) for Mohamed Ezzat Abd El-Hack
  Mohamed Ezzat Abd El-Hack , Mahmoud Alagawany , Mayada Ragab Farag and Kuldeep Dhama
  Distiller’s Dried Grains with Solubles (DDGS) as untraditional feedstuff has been available for feed industry for many years and became a nutritional and economical feed ingredient. According to recent studies, DDGS is usually used at low concentrations (10 or 15%) as a feed ingredient in laying hen diets without adverse effects on laying performance, feed utilization, nutrient digestibility, egg quality criteria and economics. Because DDGS became available in feed market in large amounts, the ability of using higher DDGS inclusion rate in poultry feed has become an interest for several researchers and poultry producers. Using such untraditional feedstuffs aims mainly to decrease the feed costs. Researchers assured that feeding higher levels of DDGS could have a significant effect on the cost of feed for poultry producers because of higher availability of DDGS and the current price fluctuations of feed ingredients. On the other hand, beneficial effects of DDGS on the environment have also been reported. These beneficial effects could be represented through mitigating harmful emissions and pollution from manure which provides production within clean atmosphere. Findings from different researches on the use of DDGS as feed ingredient for laying hens are illustrated in this review. Moreover, this study describes advanced information regarding the use of corn DDGS as untraditional feedstuff for laying hens involving its production process and nutritive value along with its useful effects on laying hens production traits, egg quality, apparent digestibility, economics and the impact on the surrounding environment in poultry house.
  Mayada Ragab Farag , Mahmoud Alagawany , Mohamed Ezzat Abd El-Hack and Kuldeep Dhama
  Spirulina (Arthrospira) is a microscopic blue-green algae and it is considered as one of the richest sources of organic nutrients that are making it a good nutritional supplement for human and animal feed worldwide. Spirulina contains good quality proteins, vitamins and minerals in addition to a wide variety of natural carotene and xanthophyll phytopigments. Owing to its unique and impressive nutrient composition, Spirulina is used as a dietary inclusion in a large scale of food products not only to enhance their nutritional qualities but also for therapeutic purposes. On this aspect, many researchers studied the beneficial effects of Spirulina and reported its enhancing potential on the productive and reproductive performance, improving general health as well as lowering the problems of different animal diseases like arthritis, diabetes, anaemia, hypertension and cardiovascular disorders. Other studies have demonstrated that Spirulina possess some promising biological activities such as antitumor, antimicrobial, antiviral, anti-inflammatory, hypocholesterolemic, radio protective and metalloprotective effects. These pharmaceutical and medicinal properties of Spirulina could be attributed to some natural constituents such as phycocyanin, carotene, tocopherols, linolenic acid and phenolic compounds that had been shown to have strong antioxidant properties and powerful scavenging activities against Reactive Oxygen Species (ROS) like superoxide and hydrogen peroxide radicals. This review illustrates the beneficial effects of Arthrospira on poultry, animals and human health and throws the light on its ability to protect the body physiological system against oxidative damage and as nutraceutical and source of potential pharmaceuticals based mainly on the highest levels of evidence available in the literature.
  Mahmoud Alagawany , Mayada Ragab Farag , Mohamed Ezzat Abd El-Hack , Elisabetta Casalino , Vincenzo Tufarelli , Maryam Sayab and Kuldeep Dhama
  Objective: The current study was conducted to assess the biological in vitro impacts of cyadox (CYA) as growth promoter on erythrocytes isolated from rabbits. Methodology: Suspensions of erythrocytes were divided into 6 groups (5 replicates each), 1st group served as control; 2nd, 3rd, 4th, 5th and 6th groups were respectively subjected to CYA at 2.5, 5, 10, 20 and 40 μg mL–1, then incubated for 3 and 6 h at 37°C and shaken gently from 3-4 times per hour. Results: The data obtained revealed that the low doses of CYA (2.5 and 5 μg mL–1) diminished the reduced glutathione (GSH) content and enhanced the catalase (CAT) and superoxide dismutase (SOD) activities even after incubation with CYA for 6 h. These concentrations also had no linear or quadratic influences on the values of malonaldehyde (MDA) and protein carbonyl (PrC) as well as the hemoglobin (Hb), adenosine triphosphate (ATP) and total protein (TP) levels in erythrocytes. Increasing the concentration of CYA (10, 20 and 40 μg mL–1) and increasing the incubation period resulted in depletion of GSH, inhibited the CAT and SOD activities and decreased the protein content in the treated RBCs while the levels of PrC, MDA, Hb, TP and ATP were increased in response to increasing the dose and incubation time. Conclusion: From these results it could be concluded that CYA may be safe at recommended doses (2.5 and 5 μg mL–1) while using at high concentrations revealed pro-oxidant properties which could in turn affect cell survival.
  Muhammad Saeed , Mohamed Ezzat Abd El-Hack , Mahmoud Alagawany , Muhammad Naveed , Muhammad Asif Arain , Muhammad Arif , Rab Nawaz Soomro , MohibUllah Kakar , Robina Manzoor , Ruchi Tiwari , Rekha Khandia , Ashok Munjal , Kumaragurubaran Karthik , Kuldeep Dhama , Hafiz Muhammad Nasir Iqbal and Chao Sun
  Green tea is an important herb and its products are extensively used in the traditional Chinese medicinal system through various formulations. Several reports have revealed its beneficial usage and medicinal aspects for various ailments. Consumption of green tea has gained special attention and popularity in various sectors of the modern era of changing lifestyle. This review aimed to extend the current knowledge on the modes of action and beneficial applications of green tea in humans and animals for safeguarding different health issues. The nutritional, immunological, pharmacological and physiological functionalities of green tea are because of the available bioactive components like caffeine, L-theanine, polyphenols/flavonoids and others. It possesses multi-beneficial potential in treating and preventing various disorders of animals and humans, as well as promoting animal (dairy, piggery and goatry) and poultry industry. The present review provides insights on the modes of action and beneficial applications of green tea, which will be useful for nutritionists, pharmacists, physiologists, researchers, veterinarians and animal and poultry producers. Future research emphasis and promotional avenues are needed to explore its potential therapeutic applications for designing appropriate pharmaceuticals, complementary medicines and effective drugs to popularize and propagate its multidimensional health benefits.
  Mayada Ragab Farag , Mahmoud Alagawany , Mohamed Ezzat Abd El-Hack , Muhammad Arif , Tugay Ayasan , Kuldeep Dhama , Amlan Patra and Kumaragurubaran Karthik
  Chromium (Cr) is one of the essential minerals which is required for improving productive performance in poultry due to its important functions in metabolism, growth and reduction of lipid and protein peroxidation. Under heat stress conditions, Cr plays a crucial role in poultry nutrition, production and health as well as enhances growth performance and quality of eggs in meat and egg type chickens, respectively. Supplementation of Cr may increase body weight gain, improve feed efficiency and there is also increase in carcass yield of broilers. Chromium is also a potent hypocholesteremic and antioxidant agent. The beneficial impacts of Cr have been linked with improved the metabolism and immune system. Dietary addition of Cr has promising impacts on the immune system through increasing relative weights of lymphoid organ such as thymus, spleen and bursa of Fabricius, declined heterophil/ lymphocyte (H/L) ratio, enhancing the Cell Mediated Immune (CMI) response and improving the antibody response versus the infectious diseases. Dietary supplementation of Cr may stimulate the secretion of digestive enzymes by improving the functions of liver and pancreas. Chromium present in many forms differs greatly in stability and oxidation states; therefore the added forms and concentrations should be managed well. Further, the increase in Cr dose in the diet could produce hazardous and toxic influences in chickens as well. This paper illustrates the positive and negative impacts of Cr including its physical and chemical proprieties, practical applications in poultry nutrition, production, enhancing immunity and health and a special reference to its toxic effects.
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