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Articles by Mohamad Saad Abd El-Karim
Total Records ( 2 ) for Mohamad Saad Abd El-Karim
  Mohamad Saad Abd El-Karim
  Cyanobacterial mats from hyper saline lakes in northern western desert, Egypt, were extracted in seven solvent and their antimicrobial activities against 10 pathogens were examined. The chemical extracts of the cyanobacterial mats exhibited antibacterial activity against 5 out of 10 tested pathogenic bacterial strains at 1 mg mL–1 concentration, whereas the resistant pathogens were highly susceptible, except Pseudomonas aeruginosa, at higher concentration of 5 mg mL–1. A total of 44 chemical compounds were detected by GC-MS. The chemical composition of cyanobacterial mats varied from one lake to the other with highest number of compounds found in Zieton Lake. Twenty five compounds were unique and were present only in extract of particular cyanobacterial mat but absent in the others. All extracts contained a suite of short chain C14-C20 fatty acids, amino acids, alcohols, esters and benzene derivatives. Phytochemical screening of cyanobacterial mats revealed the presence of terpenoids, alkaloids, saponins and glycosides. Lake Zieton is a good source of both terpenoids and glycosides compounds. Petroleum ether and n-hexane are the most effective solvents for isolate active saponins. The results indicated that cyanobacterial mats of northern western desert of Egypt have diver’s chemical and phytochemical compounds that are effective against a wide spectrum of microbes.

  Mohamad Saad Abd El-Karim and Mohamed El-Sherif Goher
  Sixteen trace metals were measured for the first time in cyanobacterial mats and its underlying sediment in eight lakes in the Northern Western desert, Egypt. Al, Ba, Cr, Fe, Pb, Mn, Ni, Cu and Zn concentrations in sediments were many times higher than in cyanobacterial mates. Fe, Al, Mn, Cu were the highest trace metals recorded in the lakes. Geo-accumulation and pollution load indices were applied to assess the human impact in lake sediments, whereas the enrichment factor index was applied for both sediment and cyanobacterial mats. The geo-accumulation index indicated that Siwa lakes sediments were unpolluted with most metals, whereas it fluctuated from unpolluted to moderate polluted with Cu and from moderated to extremely polluted with Cd. The pollution load index revealed that the lakes sediments are unpolluted. The enrichment factor index indicated that all Siwa lakes sediments are extremely enriched with Cd, Cu and Se, whereas, they are impoverishment with As, Sb, Ba, Fe, Sn and V. Cyanobacterial biofilms were highly enriched in Maraqi, Sheata and El-Bahrien, whereas the mats were highly impoverishment in Zieton and Temera. The results suggest that the natural geochemical processes may generate the high concentrations of Fe, Al, Mn and Cu in these aquatic primary producers.
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