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Articles by Mehmet Rami Helvaci
Total Records ( 2 ) for Mehmet Rami Helvaci
  Mehmet Rami Helvaci , Erdogan Soyucen , Mahmut Seyhanli , Ali Cimbiz and Munir Tumkaya
  The present study has been carried out to investigate whether or not there is an increased risk of Hepatitis B Virus (HBV) infection in persons having Hepatitis C Virus (HCV) infection. Never interferon therapy taken anti-HCV positive cases and controls have randomly been studied. In anti-HCV positives, HCVRNA via polymerase chain reaction and in HBsAg positives, HBVDNA via molecular hybridization have been studied. HCVRNA positivity has been detected in 74 of 102 cases with anti-HCV positivity. Although eight cases of HBsAg carrierity (3.63), four cases of chronic hepatitis B (1.81), three cases of HCVRNA positivity (1.36) and one case of anti-HCV positivity alone (0.45) have been detected in 220 controls, only four cases of HBsAg carrierity and no case of chronic hepatitis B have been detected in 74 cases of HCVRNA positivity (p>0.05) and no case of carrierity or chronic infection of HBV has been detected in 28 cases of anti-HCV positivity alone (p>0.05). Beside that, 24 cirrhosis, five hepatocellular carcinoma, two membranoproliferative glomerulonephritis one of which is together with rheumatoid arthritis and cirrhosis, two lichen planus, three asthma, one prolymphocytic leukemia together with cirrhosis, one idiopathic thrombocytopenic purpura, one bronchiectasis, one monoclonalgammopathy of unknown significance and two cases of non-Hodgkin`s lymphoma have been detected in 102 cases of anti-HCV positivity. Although the highly suspected relationship between HCV and many autoimmune diseases and malignancies, HCV is not a facilitating agent of HBV, either having chronic infection or being a carrier of it.
  Guven Kuvandik , Mehmet Rami Helvaci , Cahit Ozer , Engin Altintas , Hasan Kaya and Mehmet Duru
  In this study initially consecutive patients with Autoimmune Thyroiditis (AT) were taken in the Endocrinology Polyclinics. Beside that age and sex-matched patients with HCV infection and control cases were randomly studied in the Gastroenterology and Internal Medicine Polyclinics, respectively. One hundred and seventy-two patients with AT, 62 with HCV infection and 110 control cases were studied. AT was diagnosed in eight (12.9%) cases of the HCV infecteds’ group and this ratio was 11.8% (13 cases) in the control group (p>0.05). Similarly, HCV infection was detected in one (0.5%) case of AT group and this ratio was 0.9% (one case) in the control group (p>0.05). Parallel to these results, prevalences of antithyroid peroxidase and/or antithyroglobulin antibodies were detected as 29.0% (18 cases) and 32.7% (36 cases) in the HCV infecteds’ and control groups, respectively (p>0.05). As another face of the results, it was detected one case of monoclonal gammopathy of undetermined significance and one case of lichen planus in the HCV infecteds’ group. As a conclusion, HCV infection may be associated with autoimmune disorders and malignancies but not with AT.
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