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Articles by Mecit Yoruk
Total Records ( 2 ) for Mecit Yoruk
  Mecit Yoruk , Turan Karaca and Sema Uslu
  This study investigated the effects of Nigella Sativa L. (NS) and Urtica Dioica L. (UD) on the number of Mast Cells (MCs) in Carbon tetrachloride (CCl4)-treated rats. A total of 35 healthy male Sprague-Dawley rats were divided into 5 equal groups. All groups, expect control group, were injected subcutaneously with 0.8 mL CCl4 per kg body weight twice a week for 45 days and then CCl4 + UD-treated, CCl4 + NS-treated and CCl4 + UD + NS-treated rats received a daily intraperitoneal injection of 0.2 mL kg 1 NS or/and 2 mL kg 1 UD oils for 45 days starting on day 46. Thymus, spleen and mesenteric lymph nodes were sampled, stained with 1% aqueous toluidine blue and examined microscopically. The thymus, spleen and lymph nodes of CCl4-exposed animals contained significantly increased numbers of MCs compared with control group, CCl4 + UD-treated, CCl4 + NS-treated and CCl4 + UD + NS-treated rats (p< 0.05). However, when exposed rats were also treated with UD, NS or UD + NS, a decrease in MCs was observed. These results demonstrate that UD and NS decrease the number of MCs induced by CCl4 in the lymphoid tissues of rats.
  Senol Guzel , Mecit Yoruk , Kenan Gullu and Turan Karaca
  This study investigated the effects of administering Estradiol Valerate (E2V) on gonadal sex differentiation in rainbow trout (Oncorhynchus mykiss, W., 1792). Rainbow trout fry of average weight 0.320.02 g, 65 days post fertilization (dpf), which had just started to feed were supplied with a feed containing E2V at a rate of 20 mg kg-1 for 8 weeks (65-121 dpf). Fish samples were taken at random at 156 days (dpf,), 170, 191, 226 and 261 days and changes in fish gonads were analyzed histologically. At 156 dpf of the experiment, it was observed that oocyte formation had started in the fish gonads, suggesting feminization by the administration of the estradiol valerate. Intersex fish were observed at 170 dpf, while oocytes had gathered heads in gonads and sex transformation of some individuals had started at 191 dpf. Oocytes occupied the large areas of gonads and spermatogonia disappeared at 226 dpf as at 261 dpf. At the end of the experiment, sex compositions were 97% female, 3% intersex in the E2V administration group and 51% female, 49% female in the control group. There were no apparent differences between control group fish and hormone-treated fish as regards oocyte size.
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