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Articles by Md. Shahedur Rahman
Total Records ( 2 ) for Md. Shahedur Rahman
  Md. Shahedur Rahman , Md. Mahboob Hossain Khan and Md. Abu Hena Mostofa Jamal
  In this present study, it is tried to find out the antimicrobial effect and Minimum Inhibitory Concentration (MIC) of Oxalis corniculata leaf and Ocimum sanctum leaf extract against clinical isolates from urine, stool and sputum and their successive comparison with commercially, available antibiotic discs. Powdered leaves were prepared and used for extraction with various solvents, viz., methanol, ethanol and chloroform in case of Oxalis corniculata and ethanol, methanol, n-hexane and petroleum spirit in case of Ocimum santum. All the solvent extracts were evaporated to dryness in air. Using the disc diffusion method, the bacterial growth were inhibited. Among the solvent extracts tested, methanol extract of Oxalis corniculata leaf showed higher antibacterial activity compared to Erythromycin and Nalidixic acid against Staphylococci sp. whereas the methanol extract of Ocimum sanctum leaf showed higher antibacterial activity compared to CIP-5 against Staphylococcus aureus. The best MIC values were recorded to be 256 μg mL-1 against Salmonella typhi for ethanol extract of Oxalis corniculata leaf and 128 μg mL-1 against Staphylococcus aureus for the methanol extract of Ocimum sanctum leaf.
  Md. Shahedur Rahman , Md. Faizus Salehin , Md. Abu Hena Mostofa Jamal , Anzana Parvin and Md. Khasrul Alam
  The aim of this study was to evaluate the potential of Argemone mexicana (Shialkanta) extract as antimicrobial agent against bacterial isolates originated from drinking water. Effectiveness of acetone extract, ethyl acetate extract and petroleum ether extract of Argemone mexicana was determined in vitro, using agar diffusion method and MIC determination test against four (one Gram positive and three Gram negative) water borne pathogenic bacteria Escherichia coli, Shigella sp. Staphylococcus sp. and Salmonella sp. The zones of inhibition against the tested bacteria were found ranging from 8 to 16 mm, along with their respective MIC values ranging from crude to 512 μg mL-1. This study suggests that natural products derived from Argemone mexicana may contribute to the development of new antimicrobial agents.
 
 
 
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