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Articles by Md. Anwar-ul-Islam
Total Records ( 2 ) for Md. Anwar-ul-Islam
  Md. Aziz Abdur Rahman , M.A. Gafur , Md. Ekramul Islam , Md. Anwar-ul-Islam and Md. Aktar Uzzaman Chowdhury
  The subacute toxicity study of a brown antimicrobial metabolite Di (2-ethyl hexyl) Phthalate (AK2), isolated from the culture filtrate of a Streptomyces species, was carried out on long Evan`s rats. The studies include the gross general observations such as changes in body weight, haematological profiles [such as total count of red blood cells (RBC) and white blood cells (WBC), differential count of WBC, platelet count and haemoglobin (Hb) percentage], biochemical parameters of blood such as serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), serum alkaline phosphatase, uric acid and creatinine and histopathology of the liver, kidney, heart, lung and spleen of both control and experimental groups of rats. The change of haematological and biochemical parameters were statistically insignificant. No abnormalities were found in the histopathology of the liver, kidney, heart, lung and spleen in the experimental group of rats at a dose of 200 μg/rat/day for 14 consecutive days, when compared with the control group.
  Sharif Mohammad Shaheen , Fazle Rabbi Shakil Ahmed , Md. Nazir Hossen , Maruf Ahmed , Md. Shah Amran and Md. Anwar-UL-Islam
  Liposomes are being a potential carrier for advanced drug delivery. These are usually spherical lipid bilayers ranging from 50 to 1000 nm in diameter and serve as a convenient delivery vehicle for therapeutically active drug (small molecule, macromolecules like protein/peptide/Gene). Phospholipid aggregates are easy to form and vulnerable to structural manipulations, allowing for the adjustment of their properties for particular purposes. In selected cases, the application of liposomes in pharmacological therapy improves drug pharmacokinetics compared to its free form. The major advantages of the liposome application are the protection of active compounds from degradation; the increase in circulation time and the possibility to achieve partial or total selectivity. Selectivity alone improves drug potency, eliminates side effects and allows for dosage reduction. In this project the liposomes were reviewed for its nature, type, composition, preparation, mechanism of drug-transport, strategy of targeting and potential applications in respect with the advanced drug delivery system.
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