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Articles by Mazhar Qayyum
Total Records ( 2 ) for Mazhar Qayyum
  Sofia Khanum , Noor-us-Saba , Mazhar Qayyum , Badar ul Islam and Ali Abbas Qazilbash
  This study was designed to determine the prevalence of Salmonella sp. in 300 clinical samples (stool and blood) isolated from salmonellosis suspected patients. Samples were cultured on Salmonella-Shigella, MacConkey, agars enriched with Selenite F broth. Biochemical and serological confirmatory tests were carried. Salmonella sp. were found to be the principal etiological agent in 22 (7.3%) cases. Only 2 serotypes Salmonella typhi (63.6%) and Salmonella paratyphi A (36.4%) were reported. Prevalence rate was greater in blood (81.8%) than stool samples (18.2%), with higher Salmonella typhi (85.7%) than Salmonella paratyphi A (75%) isolated from positive blood samples. Incidence rates of salmonellosis were slightly higher among females as compared to males (54.5 and 45.5%, respectively), with equal gender distribution of Salmonella typhi cases, but a higher incidence of Salmonella paratyphi A among females (62.5%) than males. Of the Salmonella positive cases, 63.6% were among the 5-14 years age group, followed by 13.6% in the less than 5 years age group. Of the Salmonella typhi cases 71.4% were reported in children aged 5-14 years and 7.1% in infants under 5 years of age. For Salmonella paratyphi 50% of cases were reported among children in the 5-14 years age category and 25% in children under the age of 5 years. Fever was the most common symptom (81.8%), followed by chills (75%), abdominal pain (68%), vomiting (59%) and diarrhea (54.5%). Highest number of Salmonella typhi cases (42.9%) were reported among those living on the poverty line and 28.5% living in below the poverty line, whereas 50% of the cases of Salmonella paratyphi, reported in this study, were among those living in extreme poverty. Of the positive cases 58.8% of the children had illiterate parents. Of the children with Salmonella typhi 54.4% had illiterate parents. Of the children with Salmonella paratyphi, 65.7% had parents who lacked any sort of formal education. Among the adult population positive for Salmonella infection, 40% of them were uneducated. Of those with Salmonella typhi 66.6% were uneducated, while 50% of Salmonella paratyphi adult cases were among those who had received no formal education. In Rawalpindi, the highest incidence of salmonellosis was reported among patients residing near the Nullah Leh (35.3%). Of those patients residing in the Nullah Leh, 36.4% and 33.3% had Salmonella typhi and Salmonella paratyphi as their etiological agent, respectively. While 18.2% and 33.3% of the Salmonella typhi and Salmonella paratyphi cases, respectively, were reported from rural areas surrounding Rawalpindi. For Islamabad only a total of 5 cases of Salmonella infections were reported.
  Ateeq-ur-Rehman , Abdul Mannan , Samia Inayatullah , M. Zaeem Akhtar , Mazhar Qayyum and Bushra Mirza
  The present study assessed the different biological activities of the methanol extract of Thymus serpyllum L. (Labiateae) using bench top bioassays including brine shrimp cytotoxic, antitumor, antimicrobial, and phytotoxicity bioassays. Plant extract showed highly significant (ED50 466 ppm < 1000 ppm) impact on percentage death of brine shrimp. Agrobacterium tumefaciens (At-10)-induced tumors in potato disc tissue were inhibited (P < 0.05) significantly by methanol extract with no activity in antibacterial assay against Agrobacterium tumefaciens. EC50 value remained as 28.7 and 261.1 ppm for 12 days and 21 days of incubation respectively. Moderate antifungal activity (41-51%) was seen against five strains of fungus and no activity against any of the bacterial strain tested. Phytotoxicity to Lemna minor L. (P < 0.05) and radish seed germination and growth (P < 0.05) was observed at higher concentrations of the plant extract.
 
 
 
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