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Articles by Masih Shafa
Total Records ( 2 ) for Masih Shafa
  Daryoush Javidi and Masih Shafa
  The aim of this study was to assess the incidence of cholecystitis and its risk factors in patients undergoing Coronary Artery Bypass Grafting (CABG). In a cohort study, 574 patients undergoing CABG in Dr. Shariati Hospital from March 2003 to March 2004 were enrolled. In patients with cholecystitis signs and symptoms, ultrasonography and Liver Function Tests (LFTs) were performed. All the patients were followed for six months following the surgery. In 6 patients (1.06%) cholecystitis occurred, all during hospitalization. There were no significant differences in mean of age, BMI, CPB and cross clamp time, both sexes and patients with three vessels involvement and low cardiac output frequencies between patients with or without cholecystitis. In bivariate analysis, Frequency of patients with diabetes (83.33 vs. 12.16% with OR 36.10; 95% CI 4.16-313.67), hyperlipidemia (83.33 vs. 29.87% with OR 11.74; 95% CI 1.36-101.23) and postoperative biliary colic (83.33 vs. 3.58% with OR 70.54; 95% CI 8.03-619.53) were significantly higher in patients with cholecystitis than others. Also elevation of LFTs, Inotropic and IABP usage were significantly higher in patients with cholecystitis (All p = 0.01). When all variables were modeled using multivariable logistic regression analysis, a significant association was revealed between diabetes mellitus and post CABG cholecystitis (p = 0.01). All the patients with cholecystitis were treated by medical strategies including IV fluids, GI resting and broad spectrum antibiotics and no patients need surgical interventions. The presence of preoperative diabetes, hyperlipidemia, postoperative biliary colic, inotropic usage, elevation of LFTs and IABP could be significantly more frequent in patients with postoperative cholecystitis, although in multivariable analysis, diabetes mellitus was only detected as a significant risk factor of post CABG cholecystitis. Medical treatments for management of post-CABG cholecystitis carry acceptable results, advocating more studies.
  Ali Karami , Saeed Reza Soltani , Pooya Vatankhah , Seyd Hedayatallah Akhlagh , Mansoor Masjedi and Masih Shafa
  Perioperative renal failure is one of the major complications following coronary artery surgeries, leading to increased morbidity and mortality rates in patients; necessitating renal replacement therapy and longer hospital and ICU stay. Considering the antioxidative effects of N-Acetyl Cysteine (NAC) and vitamin C in decreasing inflammatory factors, this study was designed to evaluate and compare the protective effects of these two agents on renal function of high-risk patients undergoing coronary artery surgeries. This study was a randomized clinical trial research. Ninety patients undergoing cardiac bypass surgery, who were considered as high-risk for postoperative renal failure, were randomized into 3 groups. Group A received NAC, group B received NAC plus vitamin C and group C received Dextrose water 5% as placebo. The agents were administered during and 12 and 24 h after the operation. Serum creatinine levels one day before the operation and also on 1st, 2nd and 3rd days after the operation were recorded and compared. The results revealed no significant differences in serum creatinine levels between the three groups in any of the evaluated days. Based on the results of our study, administration of NAC or its combination with vitamin C does not affect the outcome of renal function in high-risk patients undergoing cardiac bypass surgery.
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