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Articles by Majid Karandish
Total Records ( 3 ) for Majid Karandish
  Soodeh Shockravi , Mohammad T. Jalali , Mohammad Rokn and Majid Karandish
  The aim of this trial was to determine the effect of short term calcium supplementation for 30 days on systolic and diastolic blood pressure in overweight or obese women. A double blind randomized clinical trial was conducted in 44 overweight or obese women (age: 25 ±6 years) assigned to 1000 mg day-1 elemental calcium or placebo groups. Systolic and diastolic blood pressures were measured using digital wrist monitor at baseline and after the intervention. Dietary calcium and energy intakes were estimated using 24 h recall for 3 days. No significant differences were observed in age, blood pressure, calcium and energy intakes between the groups at the baseline. No differences were observed between blood pressures before and after the intervention and also between the study groups. It seems that short term calcium supplementation (1000 mg day-1) would not have any significant effect on blood pressure in overweight or obese women.
  Mohammad Hossein Haghighizadeh , Majid Karandish , Mahdiye Ghoreishi , Farshad Soroor and Fatemeh Shirani
  Weight changes during menstrual cycle may be a cause of concern about body weight among most women. Limited data are available linking menstrual cycle and body weight changes. The aim of this study was to examine the relationship between menstrual cycles and body weight changes among university students in Ahvaz, Iran. This cross-sectional study was conducted on 50 Iranian female students aged 18-24 years. Anthropometric indices were measured according to standard protocols. During a complete menstrual cycle, weights of participants were measured each morning. Seventy eight percent of participants had normal weight (Body Mass Index: 18.5-24.9 kg m-2). Body weight increased only slightly during the three days before beginning of the menstruation. By using repeated-measures ANOVA, no statistically significant differences were found in weigh during menstrual cycle (p-value = 0.301). No statistically significant changes were found in body weight during women's menstrual cycle in a group of healthy non-obese Iranian young women. Further studies on overweight and obese women are suggested.
  Maryam Nazari , Alihossein Saberi , Majid Karandish , Niloofar Neisi , Mohammad Taha Jalali and Manoochehr Makvandi
  Background and Objective: Molecular mechanisms of most anti-obesity drugs are remained to be clear. MicroRNAs that are noncoding RNA molecules supposed to regulate biological processes concomitant to obesity and have attracted a lot of attention to themselves. The miR-27a and miR-143 expression levels in obese and non-obese rats during weight changes and L-carnitine (LC) effects on them was investigated in this study. Materials and Methods: In the present study 12 male Wistar rats were randomly divided into normal fat diet and high fat diet groups to develop obesity. After 8 weeks rats were weighted and half of diet induced obese rats were randomly selected to receive 200 mg LC kg–1 b.wt. for 4 weeks. At the end epididymal fat was isolated to investigate expression level of microRNAs by real-time PCR. Results: After 12 weeks, high fat diet in comparison with normal fat diet mediated significant decrease and increase in expression levels of miR-27a and miR-143 , respectively. These changes were modified in groups, which had received LC in a 4 weeks period. Furthermore, rats in this group gained less weight. Conclusion: Findings of this study suggest that the changes of microRNAs expression probably play a role in pathogenesis of obesity, might be modulated by means of dietary agents and supplements and modify weight gain trend.
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