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Articles by Mahmoud S. Abu-Samak
Total Records ( 1 ) for Mahmoud S. Abu-Samak
  Mahmoud S. Abu-Samak
  Central fatigue pheromone is not satisfactory to explain altered serum serotonin sSER. Thus the aim of this study is to detect some potential peripheral predictors of altered sSER at rest on the day without any exercise during winter season. One hundred and one university male students aged (21.5±1.5) year’s. Participants were divided into two groups: The NES (non exercising) and RES (regular aerobic exercising) subject groups. BMI was calculated for all subjects. Fasting blood samples were collected and tested for blood glucose, blood indices, lipid profile, serum serotonin, leptin vitamin B12, folic acid and salivary stress hormones (cortisol and DHEA). T test showed an elevation in serum serotonin levels of RES group with significant mean difference (p = 0.031) between the study groups RES and NES. Total WBC count and obesity values for mean of BMI, weight and leptin were significantly higher in NES group. Granulocytes count (R2 = 0.114), hemoglobin levels (R2 = 0.193), WBC count (R2 = 0.289), LDL levels (R2 = 0.362) and serum leptin levels (R2 = 0.423) were selected by stepwise regression analysis as predictive variables of regular aerobic exercise for serum serotonin. These predictors together explained 42% of the variance in serum serotonin. In NES potential predictors were; monocyte count (R2 = 0.102) and platelets count (R2 = 0.275). This study indicates that a positive correlation between regular aerobic exercise and serum serotonin levels in winter season is associated with significant changes in monocyte count.
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