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Articles by Mahmood, A.A.
Total Records ( 3 ) for Mahmood, A.A.
  Mahmood, A.A. , K. Sidik and I. Salmah
  The aqueous extract of Carica papaya leaves were investigated for evaluation of wound healing potential in rats. Four groups of male Sprague Dawley rats each consist of 6 animals. All animals were experimentally wounded in the posterior neck area. Blank Vaseline was applied topically to wounds of Group 1 animals. Group 2 and Group 3 rats were treated topically with 5 and 10% Vaseline, respectively. Solcoseryl jelly was applied topically to wounds of Group 4 animals as a reference. The effects of vehicles on the rate of wound healing were assessed. Wounds treated with 5 and 10% Vaseline and wounds treated with solcoseryl jelly significantly accelerate wound healing potential compared to wounds treated with Blank Vaseline. These results strongly document the beneficial effects of plant extract for the acceleration of wound healing process in rats.
  Mahmood, A.A. and M.E. Phipps
  Four groups of adult male Sprague dawley rats each consist of six animals. All animals were experimentally wounded in the dorsal neck area. Wounds of Group I rats each was treated with blank Vaseline-jelly (control), whereas wounds of Group II and Group III animals were treated with 5 and 10% Vaseline (Plantago major aqueous leaf extract in Vaseline), respectively. Wounds of Group IV rats each was treated with commercial solcoseryl-jelly as reference. The effects of vehicles on the rate of wound healing were assessed. Wounds treated with 5 and 10% Vaseline and solcoseryl–jelly significantly healed earlier and much faster as compared to wounds of control. These results strongly document the beneficial effects of plant extract for the acceleration of wound healing process.
  Mahmood, A.A. , K.Philip and I.Salmah
  The effects of methanolic extract of the rhizomes of Zingiber officinale were studied in rats for their ability to inhibit gastric lesions induced by ethanol. Animals pre-treated with ginger root extract significantly inhibited gastric lesions compared to control rats. The root extract at a dose of 1000 mg kg 1 orally exert highly significant cytoprotection against ethanol-induced gastric lesions compared to 500 mg kg 1. This cytoprotection was accompanied with increase in mucus synthesis by gastric mucosa grossly when compared with the control rats. These observations strongly suggest cytoprotective effect of the ginger extract against ethanol-induced gastric ulcer in rats.
 
 
 
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