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Articles by Mahmood A.A.
Total Records ( 2 ) for Mahmood A.A.
  Mahmood A.A. , K. Sidik , I. Salmah , K.A.R. Suzainur and K. Philip
  The aqueous extract of Ageratum conyzoides leaves was evaluation for their cytoprotective activity against ethanol-induced gastric lesions in rats. Four groups of male Sprague Dawley rats each consist of 6 animals. Group I animals were pretreated with phosphate buffer saline 5 mL kg 1 as a control, where as Group II and Group III rats were pretreated with 250 mg kg 1 and 500 mg kg 1 Ageratum conyzoides extract (5 mL kg 1), respectively. Group IV rats were pretreated with cimetidine 50 mg kg 1 as reference. After 30 min all animals were administered absolute ethanol 5 mL kg 1 orally and 15 min later all rats were sacrificed. Macroscopically, oral administration of absolute ethanol to rats pretreated with PBS significantly produced extensive hemorrhagic lesions of gastric mucosa, whereas animals pretreated with 250 mg kg 1 and 500 mg kg 1 aqueous extract or cimetidine significantly reduced the formation of gastric lesions compared to control group. Microscopically, pretreated rats with aqueous extract or cimetidine showed significantly marked inhibition of gastric lesions and marked reduction of submucosal edema compared to control group. These results strongly document the beneficial cytoprotective effects of plant extract against ethanol-induced gastric ulcer in rats.
  Mahmood A.A. , Sidik, K , Khirul Anwar A , Salmah, I. and Suzainur K.A.R.
  Four calves from each group of purebred Kedah-Kelantan (KK) cattle (Zebu); and halfbred, KK/Friesian were experimentally infested with 20,000 B. microplus larvae from first to fourth infestation at 2 months intervals. The level of tick resistance were assessed by the number of engorged ticks produced, weight of engorged ticks, eggs produced and the viability of the eggs. All animals developed a significant level of resistance in the subsequent infestation compared to the first infestation as manifested by a reduction in the above parameters. The average number of female ticks, weight of engorged female ticks per animal, the mean egg masses and hatchability of eggs was significantly lower (P<0.05) in purebred steers than their crosses form first to fourth infestation, indicating that purebred expressed a stronger acquired resistance to B. microplus ticks more readily than did their crosses.
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