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Articles by Mahboobeh Nakhaei Moghaddam
Total Records ( 2 ) for Mahboobeh Nakhaei Moghaddam
  Mahboobeh Nakhaei Moghaddam and Mohammad Nakhaei Moghaddam
  Metronidazole resistant H. pylori`s clinical isolates from biopsy specimens at a university hospital in Northeast Iran were examined. Anti-Helicobacter pylori assay was performed by the filter paper Disc Diffusion Method (DDM) on modified egg yolk emulsion agar. Twenty two (56.41%) of 39 pure isolates of H. pylori were resistant to metronidazole. Metronidazole sensitivity determination of H. pylori isolates before treating patients is essential. Protein patterns of two strains showing differences in susceptibility toward metronidazole were different which indicates variation between two strains of H. pylori.
  Mahboobeh Nakhaei Moghaddam , Mehr-angiz Khajeh Karamoddin and Mohammad Ramezani
  In tihis study, the effect of sweet basil fractions on growth of H. pylori was studied by filter paper Disc Diffusion Method (DDM) on egg yolk emulsion agar. Aqueous fraction had no activity against nine tested clinical isolates. Methanol, n-hexane and butanol fractions showed in vitro anti Helicobacter pylori effects. There are no differences (p>0.05) among anti Helicobacter pylori activity of methanol, n-hexane and butanol fractions at concentration of 1 mg, but in lower concentrations, methanol and n-hexane fractions had more antibacterial activity than butanol fraction based on Duncan test. Minimum Inhibitory Concentrations (MICs) of methanol, n-hexane and butanol fractions from leaves of sweet basil were 39.1, 41 and 117.2 μg disc-1, respectively. This study demonstrated that methanol, n-hexane and butanol fractions of sweet basil inhibited the growth of H. pylori strains in vitro.
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