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Articles by Maged S. Abdel-Kader
Total Records ( 2 ) for Maged S. Abdel-Kader
  Saleh I. Alqasoumi , Tawfik A. Al-Howiriny and Maged S. Abdel-Kader
  In a project to search for new natural hepatroprotective agents 3 plant extracts; Aloe vera, Clematis hirsute and Cucumis prophetarum, in addition to Bee Propolis were studied. The ethanol extracts of the 3 plants and propolis were subjected to hepatoprotective assay using Wistar albino rats. Liver injury induced in rats using carbon tetrachloride. The biochemical parameters; serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP) and total bilirubin were estimated as reflection of the liver condition. Based on the good results of the biochemical parameters measurements, histopathological study was performed on the liver of rats treated with Propolis and Aloe vera. The livers of rats treated with Propolis showed good protection against the toxic effect of carbon tetrachloride. On the other hand treatment with Aloe vera extract failed to restore the normal appearance of hepatocytes. All the results were compared with silymarin, as a reference hepatoprotective drug.
  Mohamed I. Aboushoer , Hoda M. Fathy , Maged S. Abdel-Kader , Gilles Goetz and Abdallah A. Omar
  Four new sesquiterpene derivatives have been isolated from the aerial parts of Cleome droserifolia. Their structures were established as 6-di(7-hydroxy, 1, 5-epoxy germacrane) (2), 4(15)-guaiane-6-ol (3), 7α-germacra-1(10), 4(15)-diene-5β, 6α-diol (4) and 4,7,8-eudesma-triol (5). In addition, a new dolabellane diterpene derivative with the naturally rare peroxy function was identified as methyl ester of 2,18-O-diacetyl-16-O-(3-hydroxy-3-methylglutaryl)-7-hydroperoxydolabella-3,8(17)diene-2,16,18 triol (7). Two known flavonoid derivatives, pinocembrin (6) and quercetin-3-glucoside,7-rhamnoside (1) were isolated from the same source. Structures were established by spectroscopic data.
 
 
 
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