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Articles by M.Y. Sugun
Total Records ( 4 ) for M.Y. Sugun
  M.Y. Sugun , G. Haruna , E.O. Irokanulo , A. Zakari and N.M. Useh
  Six batches of blackleg vaccines produced at the National Veterinary Research Institute (NVRI), Vom, Nigeria were stored at different temperatures for varying durations in amber and transparent bottles and pH values were observed to be lowered (in the transparent bottles), even at the recommended shelf life of the vaccines. Since the use of transparent bottles for packaging blackleg vaccines was accompanied by a drastic change in pH compared to amber coloured bottles, it is suggested that the use of transparent bottles to package the vaccines should be discouraged. Also, prior to bottling, it is suggested that the pH should be adjusted to 7.7-8.0, to modulate any pH drops that may occur subsequently, during storage.
  M.Y. Sugun , H.M. Kazeem , N.D.G. Ibrahim , N.M. Useh , L.B. Tekdek and I. Ajogi
  Blackleg is an economically important disease of cattle, sheep and other ruminants which is endemic in both developed and developing countries of the world. Toxins and neuraminidase produced by Clostridium chauvoei have been reported to play significant complimentary roles in the pathogenesis of the disease. In this study, the pathological changes caused by exogenous toxins produced following the culture of C. chauvoei at 24 and 48 h respectively were investigated and it was observed that the 24 h toxin produced more severe pathological changes, compared to the 48 h toxin. Necrosis was observed in the tissues examined, both grossly and histopathologically and was attributed probably to impaired cellular (mitochondrial) respiration. It was concluded that, although toxins produced by C. chauvoei play an important role in the mechanisms of blackleg, the role of leukotrienes (C4, D4 and E4), cytokines (interleukin-1, IL-1; tumour necrosis factor- , TNF- ), platelet-activating factor, interferon, complement fragments (anaphylatoxins C5a and C3a), prostaglandins and neuraminidase in the pathogenesis of C. chauvoei infection in mice need to be thoroughly investigated.
  E.A. Ogunsan , D.O. Ehizibolo , Y.G. Dashe , J.D. Jatau , F.M. Tambuwal , G.I. Dogo , N.K. Osuji and M.Y. Sugun
  An experiment was conducted to determine the effect of including Monechma ciliatum (MC) in the diet of sheep at 0 (control), 10, 20 and 30% levels. The results show that increasing the level of supplementation of MC beyond 20% decreased the feed intake and subsequently live weight gain. Except for total ash, nutrients digestibility follow similar pattern. The least cost of feed per kg live weight gain of $2.04 occurred at the 20% inclusion level and cheapest ration to feed to sheep. Whereas blood parameters differed between treatments, they were mostly within physiological limits. The metabolizable energy content of 2435 kcal/kg of the 20% diet is also the highest amongst all treatments.
  A.A. Masdooq , A.E. Salihu , A. Muazu , A.K. Habu , J. Ngbede , G. Haruna , M.Y. Sugun and U.A. Turaki
  In this study, lung samples of chickens slaugtered at abattoir in Jos South, Nigeria were tested for the presence of Pasteurella multocida and other aerobic bacteria. The identity of P. multocida was proved by mouse pathogenicity test. A total of 3000 chickens were examined at post-mortem and 500 samples with pneumonia were collected. All lungs and heart blood from 15 different commercially reared chicken flocks showed respiratory disorders. Blood agar supplemented with 10% sheep blood was used for isolation of the agents. About 32 (6.5%) P. multocida were isolated and identified. In addition, mouse pathogenicity test was carried out on P. multocida suspected isolates. About 12 (75%) of Isolates were all positive. This study showed that P. multocida is not the most prevalent bacterial infection among chicken population in Jos south.
 
 
 
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