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Articles by M.Y. Fatihu
Total Records ( 3 ) for M.Y. Fatihu
  J.S. Dalis , H.M. Kazeem , A.A. Makinde and M.Y. Fatihu
  A study was undertaken to determine the distribution of lesions of dermatophilosis on the body of cattle, sheep and goats found around Zaria and Jos in Nigeria. One thousand nine hundred and twenty cattle, 1200 goats and 800 sheep were examined for skin lesions. Skin scab samples were collected from 211 cattle, 102 goats and 20 sheep that had dermatophilosis-like lesions and processed for bacteriology at the Diagnostic Microbiology Unit of the Veterinary Teaching Hospital, Ahmadu Bello University, Zaria. One hundred and sixty seven (8.7%) cattle, 61 (5.1%) goats and 12 (1.5%) sheep were positive for Dermatophilus congolensis. Lesions of dermatophilosis were found to occur on any part of the body on cattle, sheep and goats. However, the dorsal distribution predominated in cattle (32%) whereas, lesions around the head region occurred most frequently in goats (78.9%) and sheep (50.0%). The need to study the distribution of lesions of dermatophilosis on domestic ruminants of the various ecological zones where the disease is prevalent is emphasized.
  H.M. Kazeem , D.F. Adene , L Sa’idu , P.A. Abdu , A.M. Wakawa , C.N. Kwanashie , P.H. Mamman , J. Adamu , M.Y. Fatihu and T. Joannis
  Avian Influenza (AI) strain H5N1 outbreak with very high mortality in 2 commercial poultry farms in Nigeria was subjected to further laboratory investigations to document all contributory etiological factors. Tissues from flocks on the farms located over 200 km apart were sampled for bacteriology. Haemolytic E. coli and an unidentified Gram variable rod were isolated from the first farm; Pasteurella haemolytica and haemolytic E. coli were isolated from the second farm. Antibiotic susceptibility test showed haemolytic E. coli was resistant to 6, partially to 3 and fully susceptible to Enrofloxacin (Tarivid®). Pasteurella haemolytica was resistant to 5 and susceptible to 3 antibiotics. The unidentified Gram variable pleomorph was sensitive to 10 antibiotics used. The isolation of haemolytic E. coli, in avian influenza outbreaks with high degree of antibiotic resistance is hereby documented.
  S. Adamu , M.Y. Fatihu , N.M. Useh , N.D.G. Ibrahim , M. Mamman , V.O. Sekoni and K.A.N. Esievo
  In order to investigate whether testicular pathologic changes reported in trypanosome-infected animals are related to declining testosterone concentrations or not, four White Fulani bulls (infected group) with similar ages and weights were infected with Trypanosoma vivax (T. vivax), Kudaru stock, by inoculating each, intravenously, with 2 mL of blood from an infected donor calf containing 2106 T. vivax organisms. Three other White Fulani bulls, with ages and weights similar to those of the infected group, which were uninfected, served as control group. Blood samples were collected from animals in the two groups before and after the infection to determine Packed Cell Volume (PCV) and serum testosterone profile. To carry out histopathological studies on the testes and other organs in the body of these animals, one bull from the infected group was sacrificed on day 14 Post-Infection (PI), while two bulls (one each from the infected and control groups) were sacrificed, each, on days 28, 56 and 84 PI. All animals in the infected group were parasitaemic by day 6 PI. This was followed by a gradual and progressive decrease in the values of Packed Cell Volume (PCV) and serum testosterone concentrations in these animals. PI values of these parameters in the control group remained normal relative to the pre-infection ones. The mean PI testosterone concentrations, measured in ng mL 1, in individual bulls of the infected group sacrificed on days 14, 28, 56 and 84 were 9.6±4.2, 7.8±3.7, 4.9±4.1 and 5.0±3.4, respectively. Histopathologically, severe testicular degeneration was observed in all animals in the infected group characterized by necrosis and depletion of the spermatogenic and sertoli cells in the seminiferous tubules. Leydig cells in the interstitial tissues of the testes were also severely degenerated. Severity of the lesions was related to serum testosterone concentrations as testicular degeneration was progressive from the bull that was sacrificed on day 14 PI moving through to the bull that was sacrificed on day 56 PI which had the least mean PI testosterone concentration and in which both spermatogenic and sertoli cells had undergone karyolysis and so were completely depleted. In contrast, testes of bulls in the control group were normal as both seminiferous tubules and interstitial tissues of the testes contained full complement of the spermatogenic and Leydig cells, respectively. It is concluded from this study that lowering testosterone concentration may be an aggravating factor to the degenerative changes observed in the testes of trypanosome-infected male animals.
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