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Articles by M.V.L.N. Raju
Total Records ( 2 ) for M.V.L.N. Raju
  Daida Krishna , V. Ravinder Reddy , M.V.L.N. Raju , Sanjit Kanjilal , B.V.R. Nagarjuna and R.B.N. Prasad
  The effect of dietary inclusion of solvent extracted pongamia cake (SPC) and iso propyl alcohol (IPA) treated SPC supplemented with protease (4000 U kg–1), phytase (400 U kg–1) and liver tonic (1 g kg–1) using 360 day old commercial broiler chicks. At 60 g kg–1 level, growth depression and poor FCR caused by the experimental diets could not be alleviated by enzymes/liver tonic supplementation. Dietary inclusion of SPC increased percent giblet weight. Pancreas, abdominal fat, HI titres to SRBC, CMI response to PHA-P and relative weight of spleen were similar in all the dietary groups. However, bursa weight was (p<0.05) higher in SPC supplementation with phytase (400 U kg–1) than control. The serum protein levels (p<0.05) increased in IPA treated SPC at 60 g kg–1 at 3rd week of age. The serum cholesterol level was significantly (p<0.05) higher in SPC incorporated diet with supplementation with liver tonic. The pongamia cake did not influence the activity of alkaline phosphatase. The histological changes suggested that pongamia cake leads to hepatotoxicity and nephrotoxicity in broilers. It can be concluded that, supplementation of enzymes/liver tonic cannot alleviate the toxic effects of SPC or IPA treated pongamia cake at 60 g kg–1 level in the diet.
  T. Srilatha , V. Ravinder Reddy , S. Qudratullah and M.V.L.N. Raju
  An experiment was conducted to study the effects of alpha-lipoic acid at graded levels (0, 20, 40, 60, 80 mg/kg), Vit-E (10, 50 mg/kg) and their combination in a 5 x 2 factorial design on performance, anti-oxidation and immune response of broilers. 400 day-old male broilers were divided into 10 treatment groups, each with 8 replications (5 broilers in each) and fed one of the test diets till 6 weeks of age. Supplementation of Lipoic acid in broiler diet at 80 mg/kg gave significantly (p<0.05) higher BWG than control. The humoral immune response to NDV at 28 days age significantly (p<0.05) increased with lipoic acid at 20 and 80 mg/kg plus Vit-E 50 mg/kg. At 42 days age, HI titers were significantly (p<0.05) higher in all diets supplemented with lipoic acid than control. Cell mediated immunity was significantly (p<0.05) higher on diets that contained lipoic acid at 60 and 80 mg/kg than control. Similarly, Vit-E at 50 mg/kg also had significantly (p<0.05) higher CMI than Vit-E at 10 mg/kg. Supplementation of lipoic acid and vitamin E influenced the activities of lipid peroxidase. Inclusion of lipoic acid in all dietary treatment groups increased glutathione peroxidase levels. RBC catalase levels significantly (p<0.05) increased on diets that contained lipoic acid at 60 mg/kg. It is concluded that alpha - lipoic acid at 80 mg/kg and Vitamin E at 50 mg/kg may be supplemented to the broiler diet for improved growth, antioxidant status and better immune responses.
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