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Articles by M.M. Noordin
Total Records ( 3 ) for M.M. Noordin
  A.J. Awang-Hazmi , A.B.Z. Zuki , M.M. Noordin , A. Jalila and Y. Norimah
  The study was conducted to determine the composition of mineral content of cockle (Anadara granosa) shells from 3 major cockle cultivation of West Coast of Malaysia. Three samples of cockle shells from three different sources were evaluated to determine the content of 12 macro-and micro-elements (Calcium (Ca), Carbon (C), Magnesium (Mg), Sodium (Na), Phosphorus (P), Potassium (K), Ferum (Fe), Copper (Cu), Nickel ( Ni), Zink (Zn), Boron and Silica (Si)). For convenience and ease of reference, Ca and C were combine into one unit (Calcium Carbonate, CaC) while Mg, Na, P and K was evaluated individually and Fe, Cu, Ni, Zn, B and Si were evaluated as one group (others). Analysis of elements content was done using inductively Coupled plasma, Auto Analyzer, an Atomic Absorption Spectrophotometer and Carbon Analyzer. Results in this study revealed that the mineral compositions of cockle shells from 3 different sources in West Coast of Peninsular Malaysia were consistence almost in all the samples. The percentage of CaC comprises of more than 98.7% of the total minerals content of the cockle shells of the 3 sources. About 1.3 % of the composition are comprises of Mg, Na, P, K and others (Fe, Cu, Ni, B, Zn and Si).Overall, the minerals composition of cockle shells of West Coast of Peninsular Malaysia are as followed: CaC 98.7 %, Mg 0.05%, Na 0.9%, p 0.02 and others 0.2%.
  S. Buhari , H. Kalthum , Y.M. Goh , M.M. Noordin , H.C. Chen and S.H. Gan
  Effect of single and repeated doses of tramadol on hepatic and renal functions and on pentobarbitone anesthesia was evaluated in dogs. Twenty five dogs were randomly distributed into five equal groups viz groups I and II received 3 mg kg-1 of tramadol by subcutaneous and intravenous injections, respectively during premedication alone. Groups III and IV received similar doses of tramadol during premedication which was repeated 2 h after the initial dose thorough subcutaneous and intravenous injections, respectively. Group V served as negative control. Blood samples (2 mL) were taken at 0, 2 and 4 h after tramadol’s administration while liver and kidney biopsies were taken before the surgery ended. Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) levels were significantly lowered in groups II-IV when compared to the group V at 4 h. Significant increase in AST was observed in groups I, III and V at 2 h and at 4 h in groups I and V. No significant change in kidney profile. Histopathological changes in the liver and kidney biopsies are mainly congestion, edema and cellular infiltration which occurred less frequently in groups III and IV. The volume of pentobarbitone was significantly lowered in groups III and IV. It is concluded that repeated administrations of tramadol at 3 mg kg-1, IV or SC is safe at a frequency of 2 h interval during surgery without causing irreversible hepatic and renal damage and reduced the required dose of pentobarbitone needed to maintain anaesthesia in healthy dogs.
  M.Z. Rozaini , A.B.Z. Zuki , M.M. Noordin , Y. Norimah and A. Nazrul Hakim
  The study was conducted to evaluate the macroscopic changes of burn wounds healing progress as a response to various types of honey applied topically. A total of 42 male, Sprague Dawley rats (weight 200-300 g) were used in this study. The animals were randomly divided into seven experimental groups consisted of 6 animals for each group. Macroscopic changes of the burn wounds healing progress were evaluated at day 0 post burned and subsequently at days 3, 7, 14, 21 and 28 post burned. To determine the rate of wound contraction the changes in the size of burn wounds were traced by measuring the diameter of the wound area both longitudinally and transversely across the body length using a ruler. The change in wound diameter at various time intervals was calculated as the percentage of wound area that had healed. The results obtained from this study indicated that topical application of Manuka and Melaleuca (Gelam) honeys significantly stimulated the rate of burn wound healing as assessed by increased in the rate of wound contraction and from the observation of gross appearances.
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