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Articles by M.K. Abubakar
Total Records ( 3 ) for M.K. Abubakar
  M.T. Adewumi , C.H. Njoku , Y. Saidu , M.K. Abubakar , R.A. Shehu and L.S. Bilbis
  In this study serum copper, chromium and manganese were estimated in 90 diabetic patients attending the outpatient clinic of the Federal Medical Centre, Katsina, an ancient city in North-western Nigeria and the results compared to those of apparently healthy, non-diabetic volunteers of comparable age and social status. Serum glucose level of the diabetic subjects (13.91±2.87 mmol L-1) was significantly (p<0.05) higher that the value obtained for the non-diabetic subjects (4.34±0.11 mmol L-1). The serum levels of Cr (0.19±0.05 μg L-1), Cu (0.42±0.18 μg L-1) and Mn ((1.12±0.24 μg L-1) were significantly (p<0.05) lowered in diabetic subjects. About 75% of the diabetic subjects in the study area had deficient serum levels of these metals. These results suggest that the diabetic patients in the study area have low serum levels of some antioxidant mineral elements. These observations may be an indication that the diabetic subjects are predisposed to increased oxidative onslaught.
  S.W. Hassan , F.L. Bilbis , M.J. Ladan , R.A. Umar , S.M.Dangoggo , Y. Saidu , M.K. Abubakar and U.Z. Faruk
  The aqueous and organic solvents extracts of leaves, stem barks and roots of Calotropis procera were screened for antifungal (agar dilution method) and phytochemical properties. Organic solvents extracts of the stem bark significantly (p<0.05) inhibited growth of Trichophyton rubrum and Microsporum gypseum. The petroleum ether (PE) extract however was significantly (p<0.05) active on only Trichophyton rubrum at concentrations ranging from 0.66 to 5.33 mg mL-1. All the leave extract fractions completely inhibited the growth of the tested organisms. The roots fractions of hexane (HX) and PE extracts showed significant (p<0.05) growth inhibitions of Microsporum gypseum and Aspergillus niger. All the aqueous extract fractions of the plant parts showed complete growth inhibition of all the tested organisms. Alkaloids, flavonoids, tannins, steroids, triterpenoids, saponins and saponin glycosides were detected in the leaves and roots extract fractions, with only flavonoids, triterpenoids and saponins in the stem bark extracts. The results obtained lend scientific credence for the use of the plant against fungal diseases.
  R.A. Umar , N.M. Jiya , M.J. Ladan , M.K. Abubakar , S.W. Hassan and U. Nata`ala
  We surveyed for the prevalence of anaemia, by packed cell volume and haemoglobin determinations, in a cohort of 36 pre-school children with uncomplicated Falciparum malaria in Sokoto, Nigeria. By packed cell volume, 5 (3.9%) of the children were mildly anaemic, 3 (8.3%) were moderately anaemic and 28 (77.8%) were normal. As indicated by haemoglobin levels, 6.0 (16.67%) of the study children have moderate anaemia while the remaining 30 (83.3%) were normal. There was no incidence of severe anemia in the study cohort. Comparison of Hb with PCV methods for anaemia detection indicates that the latter is more efficient in detecting prevalence of anaemia in our study subjects. Peak incidence of mild anaemia occurred in the age groups 0-12 and 49-60 months, with the lowest incidence occurring in age group 37-48 months. Peak and lowest incidence of moderate anaemia occurred in the age group 13-24 and 0-12 months, respectively. Haemoglobin levels did not vary significantly among the age groups (ANOVA, F = 1.006, p = 0.4194). Although all children less than five years of age in this setting are at risk for anaemia, the age group 13-24 months should be especially monitored for anti-anaemia interventions.
 
 
 
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