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Articles by M.G. Rajanandh
Total Records ( 7 ) for M.G. Rajanandh
  Anita Ramesh , M.G. Rajanandh , S. Thanmayee , G. SalaghaMerin , S. Suresh and K. Satish Srinivas
  The primary aim of this study was to assess the impact of patient counseling by comparing the levels of patient’s medication adherence to oral chemotherapies in patients with metastatic cancer. Sixty patients were randomized into usual care and intervention care group. Their medication adherence was assessed by Medication Adherence Rating Scale (MARS). The belief about the medication was measured by Belief about Medication Questionnaire (BMQ). Patient’s satisfaction about medication was assessed by Satisfaction with Information about medicine scale (SIMS). All the three scales were assessed at baseline and during their subsequent appointments and at end visit. Sixty patients were included for the final data analysis. No statistical significant difference between the groups with respect to socio-demographic characteristics. No patients were in stage I and II category. According to MARS criteria, adherence rate was improved from 83.4-96.6%. The BMQ-necessity scale and concern scale was related in a negative and positive way to medication adherence, respectively. Significant increase in the SIMS score was observed in both part 1 and 2 and as well as in total score in the intervention care group from baseline to end visit. At the end of the study, intervention group patients had shown a greater improvement in the MARS, BMQ and SIMS score than the usual care group patients. However, by considering the small sample size, future studies are warranted to explore changes in adherence rate with time and clinical impact of non-adherence.
  M.G. Rajanandh , A.D. Nageswari and K. Ilango
  Asthma is an inflammatory disease characterized by recurrent episodes of breathlessness and wheezing. Though inhaled corticosteroids play a vital role in the treatment of asthma, it alone or with long acting beta agonist cannot control asthma symptoms in most of the patients. The present study aims to assess the two controller medications in the form of oral tablets with inhaled corticosteroid combination in controlling forced expiratory volume in one second (FEV1) in mild to moderate persistent asthma patients. A total of 108 patients with mild to moderate asthma were enrolled in this randomized controlled study from the pulmonary medicine department of a tertiary care hospital. Patients were randomized into two groups viz., Group 1 (n = 54) and Group 2 (n = 54). Group 1 patients received Montelukast and Group 2 patients received Doxofylline. Both the groups received Budesonide inhaler. Pulmonary function test was assessed at the baseline and on follow up days. No significant difference was observed with respect to socioeconomic and educational status of patients between the groups. Significant (p<0.001) improvement in percentage predicted FEV1 after 120 days treatment was observed with both Montelukast and Doxofylline treated groups. There is no statistically significance between the groups. No major adverse events were found during the study period. The study concluded that both controller medications helped in improving lung function.
  M.G. Rajanandh , A.D. Nageswari and K. Ilango
  In many south Indian hospital, patient education by a clinical pharmacist is almost nil. The aim of this study was to assess the impact of patient education on Knowledge, Attitude, Practice (KAP) and Health Related Quality of Life (HRQoL) in asthmatics. The study also aimed to develop and validate the KAP questionnaire for asthma in south Indian set-up. Patients (n = 297) were educated on monthly basis for a period of 6 months using Global Initiative for Asthma recommended pocket guide. Impact of patient education was assessed by comparing the baseline and end visit KAP scores. On every follow-up visit, patient’s HRQoL was measured using Saint George Respiratory Questionnaire (SGRQ). The standardized cronbach’s alpha value was 0.81. The test-retest reliability was 0.89. A significant (p<0.05) improvement of KAP score was observed with respect to baseline characteristics. A significant improvement (p<0.05) in all the domains of the SGRQ score was observed from day 30 onwards. The developed KAP questionnaire was acceptable and culture fair in the tested population. Pharmacist provided patient education significantly improved patient’s KAP and HRQoL.
  M.G. Rajanandh
  Asthma has been declared as a disease of major public health importance by the World Health Organization (WHO). An optimal strategy for asthma management and prevention was implemented in 1992 by the Global Initiative for Asthma (GINA) which was constituted by WHO and the National Heart, Lungs and Blood Institute (NHLBI). Asthma has affected 300 million people worldwide and 255,000 people died of asthma in 2005. Each decade prevalence of asthma increases by 50%. The disease is predicted to affect an additional 100 million population by 2025. The present article deals with the detailed review of pathophysiology, classification, diagnosis and management of asthma.
  M.G. Rajanandh , S. Santhosh and C. Ramasamy
  Poisoning by various substances is very common. The present study aimed to evaluate the pattern of poisoning admitted to the Intensive Care Unit at SRM Medical College Hospital and Research Center. Cases were studied for a period of one year prospectively to record the incidence, age, sex, domicile distribution, education, occupation, marital and socioeconomic status. Type of poisoning with various reasons and nature of poisoning were noted. Ethical clearance was obtained and data were analyzed using descriptive statistics. The total number of poisoning cases was 224. The various types of poisons found were alcohol, antifungal drugs, antipsychotic drugs, rodenticide, organophosphates, ant killer, endosulphan, food, hair dye, kerosene, multi tablets, nail polish, oleander seeds, petrol, pain killer, Savlon liquid, scorpion bite, thinner, benzodiazepine. Maximum numbers of poisoning were of suicidal cases. Majority of poisoning cases admitted were due to organophosphates followed by oleander seeds. The study concludes that poisoning is a communal cause of hospital admissions. The most poisoning cases were observed with pesticides handled by the farmers in the agriculture fields. Strict policies against the sale and availability of pesticides must be brought in the future and poison control center, patient counseling may have a better fruitful effect in controlling the number of poisoning cases.
  M.G. Rajanandh and S. Santhosh
  The present study aimed to evaluate the pattern of poisoning at a tertiary care hospital in South India and to study the socio-demographic profile of the same. Patients who were admitted to the Intensive Care Unit at SRM Medical College Hospital and Research Center were included in the study. Patients were studied for a period of eight months retrospectively to record the incidence, age, sex, domicile distribution, education, occupation, marital and socioeconomic status. Type of poisoning, various reasons and nature of poisoning were noted. Ethical clearance was obtained before the study and then, data was collected. The data was analyzed using descriptive statistics. The total number of poisoning cases was 261. Demographic details were examined. The type of poisons was founded to be organophosphates, oleander seeds, snake bite, nail polish, rodenticide, alcohol (methanol), antifungal drugs, antipsychotic drugs, ant killer, endosulphan, food, hair dye, kerosene and miscellaneous. The study concludes that poisoning is a communal cause of hospital admissions. The most poisoning cases were observed with pesticides handled by the farmers in the agriculture fields.
  A.D. Nageswari , Uday Kiran Gampala and M.G. Rajanandh
  Classification of severity of airflow limitation in Chronic Obstructive Pulmonary Disease (COPD) does not represent the clinical consequences of COPD. Hence, combined COPD assessment should be preferred. The BODE index has recently been proposed to provide useful prognostic information. The present study aimed to identify the best component in the assessment of severity in terms of BODE index and spirometry. A prospective comparative study was carried out with 70 COPD patients recruited over 10 months at the Pulmonary Medicine outpatient department of a tertiary care hospital in Tamilnadu, India. Patients were classified according to the GOLD classification of severity of airflow limitation after performing spirometry. The BMI, dyspnea, 6 min walking distance, FEV1 and BODE index was calculated for each patient. Patients were started on inhalation therapy and pulmonary rehabilitation and followed-up every fortnightly, after 2 months of the treatment, to repeat the BODE index and spirometry. Comparison was done between the FEV1 and BODE index before and after treatment. The mean FEV1 before the treatment was 51.00 (15.21) and after the treatment, it was 48.75 (14.92). There is no statistical difference found between pre and post treatment. However, the mean BODE index score before treatment was 5.47 (1.95) and after the treatment was 4.70 (2.35). With 95% confidence interval, the level of significance was 0.001. The present study concluded that, for the assessment of severity in COPD patients, BODE index helps in a better manner than FEV1 in response to medical intervention. Calculating BODE index is simple and needs no special equipment. This makes it a potential tool of potentially widespread applicability.
 
 
 
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