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Articles by M.A. Hashim
Total Records ( 2 ) for M.A. Hashim
  S.J. Sherajee , K. Rafiq , N.S. Juyena , S. Ahmed and M.A. Hashim
  To find out the effect of diazepam and promethazine hydrochloride on respiratory rate, pulse rate, temperature and production of clinical signs in goats and also to compare the effect of 2% lignocaine hydrochloride and 0.5% bupivacaine hydrochloride during paravertebral and epidural analgesia were investigated. A total of 16 apparently healthy Black Bengal goats with body weight of 8-12 (median 9.5 kg) kg were used and allocated in 8 groups. Both diazepam and promethazine, were used as sedatives. Diazepam and promethazine produced significant reduction (P<0.01) of respiratory rate and significantly (P<0.01) increase of the pulse rate, respectively. But both drugs produced reduction of temperature insignificantly. The important clinical signs recorded using diazepam was movement of legs, neck, salivation and sleepiness whereas with promethazine only a tranquilizing effect was recorded. With 2% lignocaine hydrochloride the onset of analgesia was rapid compared to 0.5 bupivacaine hydrochloride. But the duration was significantly longer in 0.5% bupivacaine than that of 2% lignocaine hydrochloride. Muscle relaxation was better with 2% lignocaine hydrochloride compared to 0.5% bupivacaine hydrochloride. This experiment suggested that both diazepam and promethazine are suitable as pre-medicants in goats and bupivacaine seemed to be better for longer duration of analgesia compared to lignocaine which may be used for shorter and minor surgery in goats.
  M.M. Alam , S.A. Islam , Y. Mohammed , N.S. Juyena and M.A. Hashim
  The present investigation was carried out to study the comparative efficacy of two medicinal plant extracts and an antibiotic on wound healing. This was conducted on 18 female goats at BAU Veterinary Clinic. Infiltration anesthesia was performed with 2% lignocaine hydrochloride (Jasocaine®, Reneta Pharmaceuticals Ltd.) at the site of operation on lumber region. Four experimental skin wounds, two in either side of the midline plane at the lumbar region were made, each was of 2.5 cm length and 0.5 cm depth. The experimental animals were studied under 6 Groups. A series of 50 and 30% extracts of border plant (Aerva sanguinolenta), thankuni plant (Centella asiatica), antibiotic (Pronapen®) and saline were used in this experiment and these were applied twice daily to each wound. All extracts seemed to be effective for rapid healing. A 50% extracts of border plant showed the best result where healing time was 14 days whereas in antibiotic it took 16 days. In contrast more time (20 days) was required for control group. Clinical feature revealed exudation, scab formation, redness and other routine changes. Redness was more prominent in control and antibiotic treated groups compare to other groups on day 3 of wounding. Thus both border and thankuni plant extracts are very much effective for wound healing and can be applied instead of antibiotic.
 
 
 
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