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Articles by M. Shokrzadeh
Total Records ( 7 ) for M. Shokrzadeh
  A.G. Ebadi and M. Shokrzadeh
  Main purpose of this study levels of some organochlorine pesticides were determined in milk samples of mothers living in two agricultural cities of Iran (Sari and Babol in Mazandaran province) in order to assess the trends of woman workers exposure to persistent pollutants. The milk samples gathered from breastfeeding women routine determination of OCPs was performed with GC/ECD. The resulte showed the highest amounts were found for p,p`-DDE, which was 0.056 μg g-1 in fat in Sari and 0.045 μg g-1 fat in Babol , followed by β-HCH, which was 0.037 μg g-1 fat and 0.024 μg g-1 fat, respectively. The low level of OCPs in human milk as found in the present study support the Iranian policy of encouraging breast-feeding. The fact that the mother breast-feeds her child and that she originally comes from a region where DDT is still in use as a vector control agent, as well as the former use of organochlorine pesticides OCPs in agriculture, seems to be the main factors for high DDT and other OCP residues in the mothers` milk.
  M. Shokrzadeh , P. Valipour and A.G. Ebadi
  Rice is a major worldwide crop that cultivated in the most areas of the north of Iran (Mazandaran and Gillan Province). An increase in the assortment of rice varieties is making it progressively more difficult to distinguish between the many cultivars by traditional visual identification methods. The more advanced identification techniques of electrophoresis and chromatography offer an effective solution to this emerging identification dilemma. This paper reviews the application of these two evaluation techniques. An Electrophoresis analysis includes gel electrophoresis and capillary electrophoresis and compares them with a popular chromatography technique, namely reversed-phase, size exclusion anion-exchange high performance liquid chromatography (HPLC). This paper will also include an interpretation of the results.
  M. Shokrzadeh , A.G. Ebadi , S.S. Mirshafiee and M.I. Choudhary
  Camellia sinensis or tea belonging to the family of Theaceae, is widely grown. In Mazandaran provinces in the north of Iran. Tea is known in folk medicine as a medicinal plant that used as hypotensive and anti-diabetic. In this research the aqueous green leaf extract of Camellia sinensis (450 mg kg-1) showed a strong glucose lowering effect after oral administration in rats. The decrease of glycemia has reached to 30% of the control value 2 h after glucose loading. The amount of glucose absorbed in a segment jejunum in situ was 9.2±0.2 mg in presence of tea extract vs. 14.11±0.91 mg in control rats during 2 h (p<0.05). The results indicate that aqueous extract of tea has a significant anti hyperglycemic effect that may be caused in part by the reduction of intestinal glucose absorption.
  S. Ala , M. Shokrzadeh , A.M. Pur Shojah and S.S. Saeedi Saravi
  The importance of trace elements in chronic inflammatory diseases is related to their cofactor role in immune system functions and in different metabolic processes in articular tissues. The aim of this study was to compare serum levels of Cu, Zn and Zn/Cu ratio in Rheumatoid Arthritis (RA) patients with healthy volunteers in Sari Rheumatology clinic, 2007. Zn and Cu plasma concentrations were assayed using atomic absorption spectrophotometery in 40 selected RA patients sera based on sex and age compared with healthy volunteers. Statistical analysis was performed by SPSS 10 software using independent sample t-test. Zn plasma content in patient group was significantly lower (p = 0.02) than that in healthy group. Also, Cu plasma content showed no differences in comparison with healthy group (p = 0.15). Results showed no correlation between Cu and Zn plasma concentrations in patient group (p = 0.946). In contrast, significant positive correlation was found between Zn and Zn/Cu ratio (p = 0.000); but decreased Zn/Cu ratio was more influenced by diminished Zn concentration. The study showed that spreading of RA in Iranian Society is related to age, sex, career and nutrition of the patients. However, consumption of Zn and Cu supplements in RA patients may be suggested by future investigations.
  S. Khani , M. Shokrzadeh , P.k Karamoddini and S. Shahmohammadi
  The aim of this study was to evaluate the relationship between maternal serum magnesium levels and preterm birth. This Nested case-control study carried out on 20 with preterm birth and 20 women at term birth at Imam Khomeini Hospital in Sari/Iran in 2008. The women with singleton gestation and intact fetal membrane suspected to preterm labor (case group), 10 cc blood samples were drawn into syringes and sent to laboratory of the hospital immediately. Sampling for control group was same as the case group. These samples recognized as control group just as birth occurring after week 37. Finally, serum magnesium level measured. Data analyzed using χ2, t- test and OR (Odd's Ratio). There was a relationship between the number of prenatal visits (p = 0.008) and stressful events associated with preterm birth (p<0.02). Serum magnesium level was associated with preterm birth OR = 4.75, CI 95% = (0.48-46.91), Sensitivity, specificity, positive and negative predictive value of serum magnesium for preterm birth was 95, 50, 66.5 and 83.33%, respectively. Although, there was a correlation between serum magnesium levels and preterm birth, due to methodology of the study, a cohort study with the same cut off point and supplementation of magnesium in RTC studies is recommended.
  M. Shokrzadeh and A.G. Ebadi
  Garlic (Allium sativum L.) has an important dietary and medicinal role for centuries. It is a large annual plant of the Liliaceae family, which grows in most of Europe and in northern Iran. Iranian garlic is used in traditional medicine for infectious diseases, flu and as an anti-febrile. The present study tested the aqueous extract of garlic in vitro for its antibacterial activity. The extract showed concentration-dependent antibacterial activity against Staphylococcus aureus 8327. This activity was heat resistant, but the activity of freeze-dried extract gradually diminished during a 90 days period. The traditional use of Iranian garlic for infectious diseases and for controlling fever appears to be justified.
  M. Shokrzadeh and A.G. Ebadi
  Antioxidants in rice food are important for human health. However, the level of antioxidative activity of different rice grains (Oriza sativa L.) which is the staple food in Mazandaran province of Iran and is the main agricultural product exported to other countries has not previously been reported. In this preliminary investigation, the antioxidative activity in vitro of the alcoholic extract from four different kinds of rice grains have been determined by ABTS/methemoglobin method compared with Trolox, an vitamin E analog. It was found that the antioxidative activity (TEAC) as μmol per g of dry rice varied from the highest to the lowest as the followings: Tarom rice (20.22), Khazar rice (9.44), Neda rice (8.78) and Sadri rice (1.33), respectively. TEAC is distinguishly the highest in Tarom rice and remarkedly high in Khazar rice. This property may be due to the high contents of rice anthocyanins, vitamin E, tocotrienols and oryzanol. The functional chemistry, nutritional value and health benefits of antioxidants contained in rice grains, rice bran and their products should be intensively studied and characterized for their ingredients and stability. Further development for the value addition of rice as diet supplements and maximum health benefits is needed.
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