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Articles by M. Sawadogo
Total Records ( 2 ) for M. Sawadogo
  J. Sakande , E. Kabre , M. Lompo , E. Pale , J.B. Nikiema , O.G. Nacoulma , M. Sawadogo and I.P. Guissou
  In previous studies, using a bioassay-guided fractionation procedure; five fractions (E1F1, E2F2, E3F3, E4F4 and E5F5) from powdered Borassus aethiopum male inflorescences were extracted. Among these, the dichloromethane methanol extract E2F2 was found to exert significant anti-inflammatory and antipyretic activities and pro apoptotic effect. It seemed important to pursue the investigations to understand the mechanism of the anti-inflammatory activity. The anti-inflammatory activity was studied, C Reactive Protein (CRP) level in mice blood was immunoturbidimetry after inflammation induction and antioxidant activity was studied using 1,1 diphenyl picrylhydrazyl (DPPH). Phytochemical screening was carried out according to the methodology for chemical analysis for vegetable drugs. Among 3 fractions (I1; I2, I3) of E2F2, I1 was the most active with a percentage of inhibition (PI) of 80%. This anti-inflammatory activity was twice high than indometacin (PI = 40%). The I1 fraction cause significant decline of concentration of CRP compared with indometacin. The radical scavenging activities of I1 were approximately 4 times lower than ascorbic acid. Phytochemical analyses of Borassus aethiopum extracts revealed the presence of terpenoids, steroids and saponins which all have been shown to be potent anti-inflammatory and antioxidants. The present study confirmed the anti-inflammatory and antioxidant potential of Borassus aethiopum extracts with results comparable with those of standard compounds such as indometacin. Further studies are needed to isolate, purify and identify the chemical structure of the compounds responsible for anti-inflammatory and antioxidant activity.
  N. Ouédraogo , E.P. Zida , H.M. Ouédraogo , N. Sawadogo , R.W. Soalla , J.B.T. Batieno , A. Ouoba , M. Ouédraogo and M. Sawadogo
  Background and Objective: Charcoal rot caused by Macrophomina phaseolina is known to be a serious threat to cowpea in Burkina Faso. Nowadays, control strategies other than host resistance are not much effective and economical. Therefore, the present study aimed to identify among cowpea germplasm, the genotypes endowed with stable resistance to M. phaseolina. Materials and Methods: Eighty cowpea (Vigna unguiculata (L.) Walp.) genotypes including wild, landrace and inbreeding lines were screened for their resistance to Macrophomina phaseolina, the charcoal rot fungus, in greenhouse experiments in Burkina Faso. The test was performed at Kamboinse research station of the Institute of Environment and Agricultural Research (INERA), using two pathogenic strains of M. phaseolina (I2 and I4) selected from a preliminary pathogenicity test involving four isolates. Results: Eight genotypes including 58-57, Bambey-21, CB27, CB46, Gourgou, KN-1, KVx404-8-1 and TVU 14 676 inoculated with the two isolates of M. phaseolina presented high emergence rates (80-100%). After emergence, five genotypes including B05-5a, B27 07a, CB27, SP369 A Profil-39B and SP88 Profil-13A stayed free of disease during the ten-days period of the study, four genotypes including Komsare, Kaya local, 58-57 and Gaoua local-2 showed low severity (S<10%) and 11 other genotypes including KVx 295-2-124-51, Pa local-2, Boalga local, TVU 14 676, Pouytenga-3, Apagbaala, N°91 profil-4, IT82D-849, B301, TV286b profil-12 and IT 98K-317-2 showed moderate disease severity indexes (S<20%) to both isolates of M. phaseolina. Conclusion: The present study gave the opportunity to identify under artificial inoculation, two cowpea genotypes including Kaya local and SP 369A profil-39B, having high and stable resistance to M. phaseolina, among 80 tested genotypes.
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