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Articles by M. Moorthy
Total Records ( 9 ) for M. Moorthy
  B. Anitha , M. Moorthy and K. Viswanathan
  An experiment was conducted to study the inclusion of crude rice bran oil on production performance, carcass characteristics and biochemical parameters for a period of seven weeks with two hundred and sixteen commercial, straight run day-old Vencobb broiler chicks. These chicks were randomly grouped into six treatments with three replicates of twelve chicks each. The treatment groups consisted of 0% (T1), 1% (T2), 2% (T3), 3% (T4), 4% (T5) and 5% (T6) crude rice bran oil included in the broiler diet. The breast muscle cholesterol revealed no significant difference between treatment groups. Whereas the mean thigh muscle cholesterol of other treatment group birds was significantly (p<0.05) lower than those of control group. The serum total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides level did not differ significantly between treatment groups.
  P. Thirunavukkarasu , M. Moorthy and K. Viswanathan
  A study was carried out to find out the effect of induced moulting of commercial SCWL laying hens at 60, 65 and 70 weeks of age group. A control group was kept without moulting at their respective ages. The layers were reared in cages for the entire experimental period adopting standard managemental practices. The layers fed commercially available layer diet. After 28 days period of egg production (pre-moult), the layers were subjected to induced moulting by feed and water restriction followed by ad-libitum feeding and had free access to wholesome water. Seventeen hours photoperiod was provided daily through out the post-moult laying period. The birds in 70 weeks age group had higher livability among the moult induced groups and no change in body weight.
  C. Mehala and M. Moorthy
  An experiment was conducted to study the inclusion of Aloe vera and Curcuma longa and its combinations on production performance, viz., weight gain, feed intake and feed conversion ratio, carcass characteristics and biochemical parameters for a period of six weeks with two hundred and eighty commercial, straight run day-old Vencobb broiler chicks. These chicks were randomly grouped into seven treatments with four replicates of ten chicks each. The treatment groups consisted of control (T1), 0.1 percent Aloe vera powder (T2), 0. 2 percent Aloe vera powder (T3), 0.1 percent Curcuma longa powder (T4), 0.2 percent Curcuma longa powder (T5) and 0.1 percent of Aloe vera and 0.1 percent of Curcuma longa powder (T6) and 0.2 percent of Aloe vera and 0.2 percent of Curcuma longa powder (T7) included in the broiler diet. The results revealed that there was no significant difference in body weight and body weight gain between treatment groups from first week to end of the experiment period except at first week (P < 0.01). Similarly, no significant difference was recorded in feed consumption and carcass yields, but in feed conversion ratio significant (P < 0.01) difference was recorded at first week of age. Livability was 100 percent in T2 and T3 treatment groups. The mean return over feed cost differs significantly (P < 0.01) between treatment groups up to six weeks of age, which was mainly due to difference in feed cost of Aloe vera and Curcuma longa inclusion in broiler diet.
  C. Mehala and M. Moorthy
  An experiment was conducted to study the inclusion of Aloe vera and Curcuma longa and its combinations on production performance, viz., weight gain, feed intake and feed conversion ratio, carcass characteristics and biochemical parameters for a period of six weeks with two hundred and eighty commercial, straight run day-old Vencobb broiler chicks. These chicks were randomly grouped into seven treatments with four replicates of ten chicks each. The treatment groups consisted of control (T1), 0.1 percent Aloe vera powder (T2), 0.2 percent Aloe vera powder (T3), 0.1 percent Curcuma longa powder (T4), 0.2 percent Curcuma longa powder (T5) and 0.1 percent of Aloe vera and 0.1 percent of Curcuma longa powder (T6) and 0.2 percent of Aloe vera and 0.2 percent of Curcuma longa powder (T7) included in the broiler diet. The abdominal fat percentage, breast and thigh muscle cholesterol showed no significant difference between treatment groups. The serum glucose, total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides level did not differ significantly between treatment groups. Haemagglutination inhibition titre against Newcastle disease revealed significant difference (P < 0.01) between treatment groups. T2 and T3 showed higher titre value when compared with control.
  M. Moorthy , C. Mehala , S. Saravanan and S.C. Edwin
  Two hundred and eighty commercial layer chicks belonging to single hatch were purchased from local hatchery, wing banded, weighed and randomly allotted into four treatment groups with four replicates of ten chicks each. The chicks were reared in cages in a gable roofed, open sided house. All the chicks were provided with uniform floor, feeder and waterer space and were reared under standard management conditions throughout the experimental period. Treatment groups were T1- control; T2-0.1% aloe vera powder; T3-0.1% aloe vera + 0.1% Curcuma longa powder and T4-0.1% of aloe vera and 0.1% of probiotic powder There was significant (p<0.05) difference in hen housed egg production, feed conversion ratio and return over feed cost in one percent aloe vera fed group compared to other treatment groups. No significant difference was observed in feed consumption, percent hen day egg production and percent broken eggs. It can be concluded that inclusion of 0.1 percent aloe vera in White Leghorn diet is economical compared to its combination with turmeric and probiotic at 0.1 percent level.
  M. Moorthy , S. Saravanan , C. Mehala , S. Ravi , M. Ravikumar , K. Viswanathan and S.C. Edwin
  Two hundred and eighty commercial layer chicks belonging to single hatch were purchased from local hatchery, wing banded, weighed and randomly allotted into seven treatment groups with four replicates of ten chicks each. The chicks were reared in cages in a gable roofed, open sided house. All the chicks were provided with uniform floor, feeder and waterer space and were reared under standard management conditions throughout the experimental period. The experimental diet was formulated according to the standards prescribed in Bureau of Indian Standards (B.I.S., 1992). The treatment groups were T1-Control; T2-0.1% aloe vera; T3-0.1% turmeric; T4-0.1% probiotic; T5-0.1% aloe vera + 0.1% turmeric; T6-0.1% aloe vera + 0.1% probiotic and T7-0.1% turmeric + 0.1% probiotic powder. There was no significant difference in feed consumption. Hen housed egg production, hen day egg production and return over feed cost differ significantly after 40 weeks of age during the experimental period. The overall mean per cent broken eggs differ significantly (p<0.05) among treatment groups but no significant difference was observed in overall mean feed conversion ratio per dozen eggs during the experimental period.
  M. Moorthy , S. Ravi , M. Ravikuma , K. Viswanathan and S.C. Edwin
  Two hundred and ten commercial, straight run day-old Vencobb broiler chicks belonging to single hatch were purchased from local hatchery, wing banded, weighed and randomly allotted into seven treatment groups with three replicates of ten chicks each. The chicks were reared in broiler cages in a gable roofed, open sided house. All the chicks were provided with uniform floor, feeder and waterer space and were reared under standard management conditions throughout the experimental period of six weeks. The treatments were T1-Control; T2-0.2% Ginger powder; T3-0.2% Pepper powder; T4-0.2% Curry leaf powder; T5-0.2% Ginger + 0.2% pepper; T6-0.2% Ginger + 0.2% Curry leaf powder and T7-0.2% Pepper + 0.2% Curry leaf powder. The mean body weight (g/bird) of broilers at 6 weeks of age fed with different inclusion levels of dried ginger, pepper and curry leaf powder differ significantly (p<0.05) among treatment groups at six weeks of age. The feed conversion ratio was significantly (p<0.01) superior in ginger-curry leaf (T6) and pepper-curry leaf powder (T7) fed groups compared to control. But the feed consumption did not differ significantly among treatment groups because of isocaloric and isonitrogenous diet. The mean return over feed cost of T2 and T5 was significantly (p<0.01) higher when compared to other treatment groups at sixth week of age. The carcass characteristics viz. pre-slaughter, New York dressed, eviscerated weights, ready-to-cook percentage, abdominal fat percentage and giblets weight did not differ significantly between the treatment groups fed different levels of dried ginger, pepper and curry leaf powder from 1-6 weeks of age.
  M. Moorthy , S. Fakurazi and H. Ithnin
  This study was conducted to investigate and to compare liver perturbation following administration of low doses of diclofenac and ibuprofen to rats. Hundred and forty-four male Sprague Dawley rats were dosed with 3, 5 and 10 mg kg-1 diclofenac and ibuprofen in saline via intraperitoneal injection for 15 days. The control group was administered with saline in a similar manner. Four rats were euthanised every three days until day 15. Livers were removed, cleaned and a section across the right lobe was taken and fixed in 10% formalin for light microscopy and TUNEL assay. One-way ANOVA was used to analyse the data. p<0.05 was accepted as significant in this study. Three, 5 and 10 mg kg-1 diclofenac-treated groups and 5, 10 mg kg-1 ibuprofen administered groups showed significant changes compared to saline-treated group at day 15. The changes include presence of focal infiltration by neutrophils and lymphocytes and mild focal necrosis. In 5 and 10 mg kg-1 diclofenac administered groups and 10 mg kg-1 ibuprofen-treated group, apoptotic cells were seen around the perivenular regions (PV) only at day 15. However, not all the PVs were present with apoptotic cells. This study has shown that, diclofenac is probably more potent in inducing histomorphological changes at low doses. Both the drugs seem to exert time and dose dependent liver morphological alterations to the treated animals.
  M. Moorthy , S. Fakurazi and H. Ithnin
  This study was conducted to identify and to compare the mitochondrial morphological alterations in livers of rats treated with various doses of diclofenac and ibuprofen. Hundred and forty-four male Sprague Dawley rats were dosed with 3, 5 and 10 mg kg-1 diclofenac and ibuprofen in saline via intraperitoneal injection for 15 days. The control group was administered with saline in a similar manner. Four rats were euthanised every 3 days until day 15. While 200 mg kg-1 diclofenac and ibuprofen-treated rats (n = 4) were euthanized 10 h post-treatment. The livers were removed, cleaned and a section across the right lobe was taken and fixed in 4% (v/v) glutaraldehyde for electron microscopy analysis and the remaining samples were kept at -80°C for Western blot analysis. Five milligram per kilogram and 10 mg kg-1 diclofenac-administered rats for 15 days revealed the presence of enlarged mitochondria, irregular and ruptured mitochondrial membranes. While rats administered with 10 mg kg-1 ibuprofen also showed the presence of mitochondria with irregular membrane structure and ruptured membranes. Western blotting analysis of mitochondrial fractions revealed the expression of cytochrome c in all samples and complete absence of cytochrome c expression in the cytosolic fraction of all samples after day 15. Analysis in 200 mg kg-1 diclofenac and ibuprofen-treated groups, revealed expression of cytochrome c in both mitochondrial and cytosolic fractions. This observation indicates that both diclofenac and ibuprofen may alter the morphology of mitochondria, leading to cytochrome c release into the cytosol. Further studies needs to be conducted to investigate on the activity of the mitochondria following both treatments.
 
 
 
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