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Articles by M. Mazandarani
Total Records ( 4 ) for M. Mazandarani
  T. Dadgar , M. Asmar , A. Saifi , M. Mazandarani , H. Bayat , A. Moradi , M. Bazueri and E. Ghaemi
  Bacterial resistance to antibiotics is a serious global problem and includes strains of beta-lactam-resistant Staphylococcus aureus and methicillin-resistant S. aureus (MRSA). Novel antimicrobials and/or new approaches to combat the problem are urgently needed. The aim of this study was to investigate the antimicrobial activity of alcoholic and aqueous extract of 23 medical plants species of Golestan province on clinical and standard stains of MRSA and MSSA. Twenty three medicinal plants were collected from their natural habitat in Golestan province in north of Iran. Their ethanolic and aqueous extract obtained by percolation methods. Antibacterial effects were assessed by disk diffusion method and the Minimum Inhibitory Concentration (MIC) of the extracts was determined by the micro broth dilution against 14 clinical and standard strains of methicillin resistant and sensitive of Staphylococcus aureus. The ethanolic and aqueous extract of 8, plants showed best anti staphylococcal effect, respectively. The ethanolic extract of Artemisia, herbaalba, Nigella sativa, Punica granatum, possed the most outstanding in vitro antibacterial activity which the maximum inhibition zone was 22.4-18 mm, respectively and the lowest MIC values was measured in Punica granatum, as 0.01 mg mL-1 against MRSA The results showed that ethanolic extract had better antibacterial effect than aqueous extract and anti staphylococcal activity of Ethanolic extract of plants against MRSA was better than MSSA strains. Ethanolic and aqueous extract of Punica granatum had the best antibacterial activity against the tested microorganisms. The result obtained from these plants might be considered sufficient for further studies.
  M. Mazandarani , S. Yassaghi , M.B. Rezaei , A.R Mansourian and E.O. Ghaemi
  This research project was a field observation study and we examined the ethnobotany, phenology and antibacterial effects of two species of H. perforatum and H. androsaemum. The investigation of phenology showed these plants initiate vegetative stage at the early April to June, with wide dispersal and density in humid temperate to dry-cool climate in heavy texture soil and non saline in 10-2400 m from sea level. The ethanolic extracts of flowering aerial parts of either species exhibited a good antibacterial activity against Staphylococcus aureus and Entrococcus faecalis, with the diameters of growth inhibition zone in the rang 25, 26 mm in H. perforatum and 16, 20 mm in H. androsaemum, respectively. Weak antibacterial effects were seen in the infusion and aqueous extracts. Present data show that Gram-negative bacteria are resistant toward all of different extracts. We conclude that the extract of Hypericum species should be used when the etiological agent of infection is a Gram-positive bacteria.
  B. Behmanesh , G.A. Heshmati , M. Mazandarani , M.B. Rezaei , A.R. Ahmadi , E.O. Ghaemi and S. Bakhshandeh Nosrat
  The chemical composition and antibacterial effect of Artemisia siberi essential oil were studied in this research. The composition of essential oil from aerial parts was analyzed by GC/MS and its antibacterial effect were determined by disc diffusion method. Artemisia ketone (48.5%), 1, 8-cineole (19.7%), selin-11-en-4-a-ol (4.6%) and lavandulon (2.8%) were the major constituents of this herbal medicine. Inhibitory zone against Pseudomonas aeroginosa, Staphylococcus aureus and Escherichia coli around discs contained 100 mg mL-1 of Artemisia siberi essential oil were 18, 13 and 12 mm, respectively. Further studies for the determination of anti Pseudomonas infection in animal model are suggested.
  B. Amoian , A.A. Moghadamnia , M. Mazandarani , M.M. Amoian and S. Mehrmanesh
  The aim of this study is to investigate the efficacy of Calendula officinal extract toothpaste in reducing gingival inflammation and plaque formation. A total of 40 volunteers with established gingivitis (21 males and 19 females, with a mean age of 28.8±3.28) were included in this prospective, double blind clinical study. They were randomly assigned to 2 treatment groups: group 1 (n = 20), treated with a base dentifrice as the control toothpaste; group 2 (n = 20), treated with Calendula flower extract tooth paste. Subjects were instructed to brush their teeth three times daily using the Bass method and their assigned tooth paste for 4 weeks. Data was collected at baseline and at increment of 2, 3 and 4 weeks. This data includes an analysis of Plaque Index (PI), Gingival Index (GI) and Bleeding on Probing (BoP). The present study was carried out at Babol Dental School, Babol, Iran between December 2007 and October 2008. Over a period of 4 weeks, all indices were significantly decreased. A substantial reduction in PI was noted for group 2 (1.63 vs. 1.42) throughout the follow-up period, this reduction was seen in GI (1.23 vs. 0.66) and BoP (1.29 vs. 0.64) for group 2. Brushing with calendula toothpaste led to significant reductions in PI, GI and BoP. This treatment could therefore, be recommended as an adjunctive procedure effective for the improvement of gingival inflammation.
 
 
 
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