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Articles by M. Khanavi
Total Records ( 3 ) for M. Khanavi
  S. Jafari , S. Esfahani , M.R. Fazeli , H. Jamalifar , M. Samadi , N. Samadi , A. Najarian Toosi , M.R. Shams Ardekani and M. Khanavi
  The volatile oil from Citrus aurantifolia (Christim) Swingle (lime) fruit peel is abundantly used as flavoring agent in food industries. In this study chemical composition and antimicrobial activity of essential oil Citrus aurantifolia against food-borne pathogens was determined to investigate its potential in reducing microbial population of cream-filled baked goods. Fifty componenets were identified in Citrus aurantifolia essential oil by GC-MS analysis and limonene, α-terpineol and γ-terpinen were the most abundant constituents. The results of bioburden determination showed that cream-filled cakes and pastries were mainly contaminated with Staphylococcus epidermidis and Bacillus subtilis. Lime essential oil showed potent antibacterial activity against spoilage bacteria. MICs (Minimum Inhibitory Concentration) of lime essential oil against S. epidermidis and B. subtilis were determined 4 and 8 μL disc-1, respectively. By using 16 and 32 μL mL-1 of essential oil, more than 99.9% reduction in S. epidermidis and B. subtilis counts were observed, respectively. The use of Citrus aurantifolia essential oil in concentrations higher than MIC value can improve shelf life of cream-filled cakes and pastries. According to our results, lime oil can increase the time needed for the spoilage bacteria to reach concentrations able to produce a perceivable spoilage and it may consequently reduce the risk of diseases associated with consumption of contaminated products.
  M. Khanavi , H. Azimi , S. Ghiasi , S. Hassani , R. Rahimi , S. Nikfar , Y. Ajani , M.R. Shams-Ardekani and M. Abdollahi
  In the present study, cAMP and cGMP phosphodiesterase inhibitory (PDEI) activities of the ethanolic extracts of nineteen plants of Traditional Iranian Medicine (TIM) with aphrodisiac effects were investigated. The plants were extracted in a similar way and then three concentrations (0. 1, 1, 5 mg mL-1) from each were tested for PDEI activity against control and sildenafil. Among plants tested, 8 including Allium cepa, Trigonella foenum-graecum, Brassica rapa, Alpinia officinarum, Tribulus terrestris, Urtica pilulifera, Linum usitatissimum and Zingiber zerumbet exhibited a significant dose-dependent cAMP-PDEI activity and 6 including A. cepa, A. officinarum, T. terrestris, L. usitatissimum, Withania somnifera and Z. zerumbet gave a remarkable dose-dependent cGMP-PDEI effects in comparison to control. Among tested herbs, Zingiber officinalis and Peganum harmala at dose of 5 mg mL-1 demonstrated better cGMP-PDEI in comparison to sildenafil. The results of this study give idea for discovery of safe and better drugs in management of erectile dysfunction.
  M. Khanavi , G. Moghaddam , M.R. Oveisi , N. Sadeghi , B. Jannat , M. Rostami , M.A. Saadat and M. Hajimahmoodi
  Pomegranate (Punica granatum L.) is native to the Mediterranean region and has been used extensively as a medicine in many counties. Hyperoside is known as an important flavonoid with antioxidant activity and anti hypertension effect. Anthocyanins are the active component in several herbal medicines, thus accurate measurement of hyperoside and anthocyanins, along with their degradation indices, is very useful to food technologists and horticulturists. The aim of the current study was to determine the antioxidant capacity as hyperoside and anthocyanin content of ten different Iranian pomegranate cultivars. Spectroscopic analyses of the pomegranate showed Black peel cultivar had the highest hyperoside content (25.93±2.87, 620.41±30.32 mg/100 g) in its pulp and peel, respectively. Based on this study, the amounts of anthocyanin in pulp ranged between 1.56±0.05 and 3.89±0.07 mg g-1 which related to Sweet white peel and Sweet alac cultivars, respectively. More over the highest and also the lowest peel anthocyanin contents related to these cultivars. The results revealed that the hyperoside and also anthocyanin peel content of each variety is higher than its pulp content. In addition the potency of black peel (Medicinal pomegranate) and Sweet alac cultivars for prevention of coronary heart disease and hypertension were presented.
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