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Articles by M. Kadkhodaee
Total Records ( 2 ) for M. Kadkhodaee
  F. Rahim , G. Saki , B. Ghavamizadeh , A. Jafaee and M. Kadkhodaee
  This study was conducted in vitro to show the effect of oxamate on motility and fertility of the mouse. The spermatozoa were extracted from the caudal part of epididymis. The study animals divided into four groups: (1) control group in TYH medium+5 mg mL-1 BSA ; (2) test groups in TYH medium in which contain 10 Mm oxamate; (3) test groups in TYH medium in which contain 20 Mm oxamate and (4) test groups in TYH medium in which contain 30 Mm oxamate. All four groups were incubated for 90 min to obtain capacitation. Further their motility was checked after incubation time. The mice were super ovulated with PMSG and HCG hormones to obtain oocytes. Total of 600 oocytes were collected and cultured in drops of KSOM medium+5 mg mL-1 BSA, then for fertilization process received spermatozoa from different groups of mentioned above. After 24-26 h, the rate of fertilization was checked. The results of this research indicated that oxamate at the concentration of 20 and 30 Mm significantly reduce (p<0.05) the progress of motility and fertility. Statistical analysis showed that percentage of the sperm progress motility in both concentration of 20 and 30 Mm was significantly differ (p<0.05) in compare with control group and in concentration of 10 Mm, respectively. The same results were obtained in the case of fertility. These findings suggested that oxamate has an inhibitory role on motility and fertility of mouse sperm.
  J.M. Malekzadeh , S.A. Keshavarz , F. Siassi , M. Eshraghian , M. Kadkhodaee , A.R. Dorosty , A. Aliehpour and M. Chamari
  Recently, studies have focused on the effects of dietary calcium on the weight and fatness. Some of these studies have indicated that there is negative relationship between dietary calcium and body fat, while others have reported no such effects. There are also controversies over serum parathyroid hormone, as its mechanism, on body fat and weight. The objective of the present study was to evaluate the effects of three dietary calcium levels (0.2%, 0.5% or 1.2% Ca2+) on body fat and weight gain in male Sprague-Dawley rats, using same diet composition for nutrients other than calcium. The study duration was 72 days. At the end, truncal blood samples were drawn from decapitated rats to measure the effects of diets on serum calcium, PTH and vitamin D. The carcasses were minced and homogenized to measure their body fat percent by the methods of Soxhelet. There were no significant effects of dietary calcium on food intake (p>0.05), body weight gain (p>0.05) or carcass fat content (p>0.05), while the serum PTH levels were inversely related to calcium intake (p<0.05). In conclusion, our findings do not support the effects of dietary calcium and parathyroid hormone on body fat and weight.
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