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Articles by M. Idu
Total Records ( 11 ) for M. Idu
  E.S. Orhue , M. Idu , J.E. Ataman and L.E. Ebite
  This study investigated the possible toxicity of consumption of the leaf by determining a variety of serum biochemical parameters in liver and renal function tests, haematological and physical parameters. A 5 week repeated dose toxicity of Jatropha tanjorensis leave powder was carried out in rabbits. Forty animals, male and female, were administered feed mash plus ground J. tanjorensis leaf powder in graded concentrations of 0, 5, 10 and 25%. All rabbits survived at the end of the study and results showed no significant alteration in average body weight in the treatment groups when compared with the control group. The haemoglobin, hematocrit, platelets and platelet cell distribution width in the female group, showed significant increase between the control and the treated groups. This is an indication of an improved bone marrow function. No severe histopathologic indicator was recorded.
  M. Idu , C.A. Omonhinmin and H.I. Onyibe
  To establish propagation test and nursery establishment protocols for Hura crepitans , Various concentrations and timing regimes were performed on the seeds of Hura crepitans using growth hormones; Thiourea, Gibberellic acid and Coumain. Gibberellic acid pretreated seeds recorded high cumulative germination (100%) and germination energy (95%). Similarly, high percentages were recorded for Thiourea. However, Coumarin showed poor germination as well as recorded high percentage of abnormal seedlings (90%), a poor option for nursery establish of Hura crepitans. Ranked mean for the germinated seedlings was significant at p<0.05 for Thiourea and Gibberellic acid treatments.
  M. Idu , J.U. Chokor and O. Timothy
  The present study embodies data on the seed morphometrics and effect of five hormones viz., thiourea, gibberellin, coumarin, 1-naphthalene acetic acid and Indole butyric acid on the germination of Digitaria exilis. The hormonal treatment was carried out under different concentrations, time regimes and continuous light and dark conditions. The highest percentage germination (78%) was recorded in seeds treated with Thiourea (0.01 mg L-1) for 15 min and 0.0001 mg L-1 for 60 min under continuous dark condition while lowest percentage germination (25%) was recorded in seeds treated with 1-naphthalene acetic acid (0.001 mg L-1) for 60 min under continuous light condition.
  M. Idu , A.C. Omonhinmin and H.I. Onyibe
  The phenology, seed germination, seedling development and evaluation were carried out on the seeds of Hura cepitans. The phenological data describes Hura crepitans seeds as 0.94 g in weight, 2.3x2.2x.48 cm in size; 3.6 cm3 mean volume, of 78% moisture level. The capsule of length 8 cm contains 7-16 seeds. The seeds are circular in shape, smooth, glabrous and glossy in texture with a capsule depth of 2.5 cm and a brownish testa. The plant flowers and fruits from the end of October to the end of June. To break dormancy, investigations on the stimulatory effect of chemical scarifications were analyzed. Methanol pre-treatment recorded the highest of 70% germination. Comparatively, some of the pretreatments showed better germination energy and vigour than the control. Such pretreatments are good for germination and nursery establishment of the species.
  M. Idu , E.K.I. Omogbai , F. Amaechina and J.E. Ataman
  The effect of the aqueous extract of the leaves of Stachytarpheta jamaicensis (L.) Vahl. on blood pressure was investigated in anaesthetized normotensive male rabbits. The extract was administered intravenously at doses ranging from 2.5-80 mg kg-1. The extract caused a dose-dependent fall in blood pressure and heart rate. 2.5 mg kg-1 of the extract reduced the Mean Arterial Pressure (MAP) from the initial 102.8±4.2 to 96.6±7.3 mmHg and the Heart Rate (HR) from 398.3±8.3 beats/min to 373.1±9.7 beats/min. 80 mg kg-1 reduced MAP and HR to 38.9±3.1 mmHg and 178.3±83.7 beats/min, respectively. Neither atropine nor promethazine inhibited the hypotensive effect of the extract. The acute hypotensive effect of the extract may be partly due to the negative chronotropic effect or to a direct effect on vascular smooth muscle.
  M. Idu , O. Timothy , E.K.I. Omogbai and F. Amaechina
  The hypotensive and acute toxicity activities of methanol extract of B. axillaris leaves, obtained by soxhlet extraction, were analyzed using animal models. The extract exhibited a dose-dependent reduction in rabbit blood pressure. Basal mean arterial pressure of 115.67 ± 3.60 mm Hg was progressively reduced to 106.22 ± 3.13 and 69.3 ± 2.59 mm Hg by 2.5 and 20 mg kg-1 doses of extract, respectively. Hematological parameters in Wister rats treated with 1, 2 and 4 g kg-1 of extract showed no significant difference, p>0.05. However, lethal dosage was obtained at 8 g kg-1. The need for further evaluation and prospect of the plant in health care was also discussed.
  M. Idu , B.C. Ndukwu and O.O. Osemwegie
  Ethno-floristic studies of Ethiope Council area of Delta State, Nigeria was carried out with a view to take inventory of the flora and establish the varying ways plants are used by the aborigines. A total of 145 plant species distributed into 51 angiosperm families were recorded in the area. The studies indicate that the indigenous people have developed various ways and methods for the utilization of their plant resources. Efforts were made to track and document the customary knowledge and use of these plants. The information is intended to contribute to the current global efforts at safeguarding the loss of indigenous values and knowledge of biological resources.
  M. Idu and H.I. Onyibe
  The ergastic substances of 93 angiospermous seed samples belonging to the family Fabaceae have been investigated. Forty four and 86 of the samples indicated positive for alkaloid and fats and oil respectively while 34 samples indicated the presence of protein and tannins. The morphological characteristics of starch grains i.e., size, shape, helium striation, percentage of different types and their frequency are given. Of the 93 seed samples 27 are found to contain starch grain. However, the starch grains are restricted mainly to the herbaceous habit. In general arborescent taxa either lack starch grains or such grains are of sparing occurrence.
  M. Idu and B.C. Ndukwu
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  M. Idu , E.K.I. Omogbai , G.E. Aghimien , F. Amaechina , O. Timothy and S.E. Omonigho
  The phytochemical analysis on stems of Stachytarpheta jamaicensis proved the presence of secondary metabolites, including; tannins, saponins and flavonoids Crude concentrations of aqueous extract of stem showed antimicrobial activity on Bacillus subtilis, Escherichia coli, Candida albicans, Staphylococcus aureus, Pseudomonas aureginosa and slight activity on Proteus vulgaris while the alcoholic extract had almost similar activity, but lesser activity was observed on Escherichia coli.
  A.O. Akhigbe , M. Idu , E.S. Orhue , J.E. Ataman and S.O. Ehimwenman
  Toxicological study of Jatropha tanjorensis leaves was conducted by evaluating changes in weight, biochemical and ultrasonographic parameters of rabbits that have been administered varying concentrations (0, 5, 10 and 25%) of the ground leaves mixed with feed-mash for a period of 30 days. There was no significant difference (p<0.05) in weight of rabbits. Renal function tests revealed that there was a significant reduction of serum urea concentration in the male rabbits (p<0.05) from 38.33 in group C to 18.33 in group D. This suggests that the amount of J. tanjorensis plant powder used in this study could interfere positively with the filtration function of the kidney in rabbits. The ultrasound picture of kidney, heart and spleen showed no significant change from the control, where as there was reduction in the size of the liver with increased echogenicity when compared with the control. This may be an indication of hepatic toxicity.
 
 
 
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