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Articles by M. Gholipour
Total Records ( 2 ) for M. Gholipour
  H. Motamedi , E. Darabpour , M. Gholipour and S.M. Seyyed Nejad
  Plantago ovata (Plantaginaceae) and Oliveria decumbens (Umbliferae) are of important medicinal plants in Iran which have been used in traditional medicine. The aim of present study was to consider antibacterial properties of ethanolic and methanolic extracts of seed husk of Plantago ovata and aerial part of Oliveria decumbens. For this purpose, the 50 to 400 mg mL-1 concentration of these extracts were assayed against six Gram-negative and eight Gram-positive bacteria by disc diffusion method. Synthetic Antibiotic discs were used as control. Staphylococcus epidermidis and Staphylococcus aureus were the most sensitive species to the ethanolic and methanolic extracts of Plantago ovata while Pseudomonas aeruginosa was the most resistant to these extracts. Furthermore, Escherichia coli and Proteus mirabilis have shown resistance to ethanolic extract of this plant. Ethanolic extract of Oliveria decumbens was effective against all of tested bacteria and S. aureus was the most sensitive strain. In the case of the methanolic extract, Salmonella typhi, P. aeruginosa and P. mirabilis were more resistant than the others. The MIC (Minimal Inhibitory Concentration) and MBC (Minimal Bactericidal Concentration) values for Oliveria decumbens extracts against S. aureus were same (20 mg mL-1), whereas against Streptococcus pyogenes were different. Also, MIC for ethanolic extract of Plantago Ovata against S. aureus and Bordetella bronchiseptica were same (20 mg mL-1), whereas for methanolic extract were 20 and 10 mg mL-1, respectively. The MBC for these two bacteria weren’t found (>200 mg mL-1). On the basis of these results it can say that these plants have proper antibacterial effect and can be considered as a new source of antibiotic discovery and development for infectious disease treatment purposes.
  A. Hassanpour , M. Gholipour and A. Rezaie
  The present study was conducted in order to examine the effect of monensin on serum level of haptoglubolin in pregnant dairy cattle. About 20 heads of pregnant dairy cattle (5 months pregnant) were selected in two, control and treatment, groups. The cattle of two groups were in the same situation considering management, production and age. In treatment group about 200 mg monensin was added to the diet of each cattle head in addition to the ordinary diet of control group. On days of 0, 30, 90, 120, time of parturition and 2 weeks after parturition the blood samples was collected from jugular vein and then serum was separated. In all serum samples the haptoglobin serum level was measured by biochemical kit. The average of serum haptoglobin did not have meaningful difference between two groups on day of zero but in care group there was decrease in serum haptoglobin after the day of 30 and on the day of 30 the difference between two groups was not significant (p = 0.066). On the day of 90 and 120 this difference was significant and it was p = 0.037 and p = 0.04, respectively. On parturition time, haptoglobin serum level increased in two groups and this increase in treatment group was less than control group which was nonsignificant (p = 0.003) and 2 weeks after parturition it was low in treatment group which was not significant (p = 0.586). The changes of serum haptoglobin in control group was not meaningful on different times but in treatment group the serum changes was significant on days of zero and 30 (p = 0.04). The mean serum level of this protein in affected cattle to parturition diseases was greater than healthy carrel in two groups. Final result was that adding monensin to pregnant cattle diet led to decrease of haptoglobin serum level, 4 month before parturition.
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