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Articles by M. Eghbali
Total Records ( 2 ) for M. Eghbali
  M. Eghbali , M. Ghane , M. Mirinargesi and A. Zare Mehrjardi
  Epstein Barr Virus (EBV) infects more than 90% of the world's human population. An association is proposed between EBV infection and occurrence of breast cancer, with a large difference in the results reported by different researchers. This study aimed to investigate the frequency of EBV among benign and malignant breast tumors. A total of 24 carcinomas and 24 fibroadenomas paraffin embedded tumoral tissue samples were obtained from the pathology sections of Toos and Firoozgar hospitals in Tehran, Iran. All samples had been collected from patients from June 2011 to February 2012. DNA was extracted from all samples and their infection with EBV was examined by PCR technique. The results obtained by this study showed that 4 out of 24 carcinoma samples (16.6%) were infected by EBV, while the number of fibroadenoma samples infected by this virus was 1 (4.1%). The frequency of EBV infection was different among malignant and benign tumors. However, no association was observed between EBV infection and the formation of malignant or benign tumors based on the Chi-square test. In relation to some other studies, this analysis does not confirm any association between EBV infection and breast cancer occurrence. However, due to the high frequency of EBV infection among breast cancer patients, future studies are needed to elucidate the possible role of the virus in the disease.
  M. Eghbali , S.M. Alavi-Shoushtari and S. Asri Rezaii
  To investigate the effects of copper and superoxide dismutase (SOD) content of seminal plasma on buffalo semen characteristics, 54 semen samples collected from buffalo bulls by a bovine artificial vagina were used. Semen characteristics (motility, viability, morphology, concentration and volume) were recorded. Seminal plasma was harvested by centrifugation and kept frozen until analysis. Seminal plasma copper content was determined by atomic absorption procedure and SOD was measured by using a kit. The mean total copper value of seminal plasma was recorded as 2.51 ± 0.04 mg kg-1 (Mean ± SEM) and the mean total SOD values was 39.02 ± 0.81 IU mL-1. To reduce the range of variability, the data were categorized according to their motility records in 3 groups of Excellent (Ex, >90% motile, n = 33), Good (Go, 80-89% motile, n = 15) and Moderate (Mo, <79% motile, n = 6). The mean motility, viability, copper and SOD values in Ex group was recorded as 92.24 ± 0.51%, 94.00 ± 0.48%, 2.56 ± 0.04 mg kg-1 and 39.52 ± 0.57 IU mL-1, respectively. These values were 81.66 ± 0.62%, 85.26 ± 0.95%, 2.38 ± 0.11 mg kg-1 and 36.48 ± 1.51 IU mL-1 in Go group and 71.66 ± 1.05%, 77.00 ± 2.94%, 2.55 ± 0.10 mg kg-1 and 50.66 ± 2.51 in Mo group, respectively. The mean copper value in Ex group was highly (r = 0.600) correlated with SOD and correlated with sperm motility (r = 0.372) and viability (r = 0.363), while, in Go group it was highly correlated (r = 0.945) with SOD and sperm viability (r = 0.652) and in Mo group it was correlated (r = 0.874) with semen volume only. The mean SOD values in Ex group was highly correlated with sperm motility (r = 0.492) and viability (r = 0.490) and mean copper values, in Go group, it was highly correlated whit sperm viability (r = 0.659) and mean copper values and in Mo group it had no significant correlations with semen parameters. These results suggest that copper and SOD content of the buffalo seminal plasma have an influence on the sperm motility and viability which are the most important factors in semen fertility.
 
 
 
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