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Articles by M. Alagawany
Total Records ( 5 ) for M. Alagawany
  E.A. Ashour , M. Alagawany , F.M. Reda and M.E. Abd El-Hack
  This study was performed to investigate the effect of dietary supplementation with Yucca schidigera Extract (YE) as growth promoter and natural antioxidant on performance, carcass characteristics, serum metabolites and liver oxidative status in growing rabbits. A total of 80, New Zealand White (NZW) rabbits at 5 weeks of age were randomly assigned to four treatments with four replicates. The dietary treatments consisted of the basal diet as control, YE groups receiving 200, 400 and 600 g kg-1 YE added to the basal diet. Body weights of rabbits were measured at 5, 7, 9 and 13 weeks, feed intake was measured at the same periods and feed conversion was calculated, accordingly. At weeks13, carcass characteristics, blood profile and antioxidant status in liver were determined. Live Body Weight (LBW) and Body Weight Gain (BWG) were not significantly influenced by the dietary treatments. Giblets percentage and relative weights (organ weight, g/100 g of body weight) of the heart, liver, spleen and lungs of rabbits at 13 weeks were not affected by dietary treatments. However, carcass yield percentage and relative organs of kidneys, skin and legs were statistically (p<0.05) influenced by dietary treatments. There were no differences (p<0.05) in total protein, globulin, AST, ALT and LDL-cholesterol due to treatments. While, the other blood parameters were statistically affected by YE supplementation. Dietary supplementation of YE to basal diet exhibited a significantly positive effect on immune related parameters (albumin, ALB immunoglobulin, IgG and IgM) and serum ammonia. The lowest value of ammonia achieved by animals fed diet contained YE 200 mg kg-1 diet. Rabbits fed YE 400 and 600 mg kg-1 of diet produced the best results of total-cholesterol in blood versus other diets, also HDL-cholesterol was gradually decreased with increasing YE supplementation. Hepatic Superoxide Dismutase (SOD) activity and reduced Glutathione (GSH), Malondialdehyde (MDA) concentrations were not significantly affected by the different levels of YE. But lipid peroxidation was slightly decreased with increasing YE supplementation. Dietary supplementation of YE to control diet exhibited a significantly positive effect on Glutathione Peroxidase (GSH-Px) and Catalase (CAT) activities. It could be conducted that, rabbits fed diet supplemented with YE did not affect growth performance in general but improved the immunity responses, in addition, animals fed diet supplemented with phytogenic additive had lower ammonia in blood, MDA in liver and increased hepatic antioxidant activities.
  M. Alagawany , Mayada R. Farag , M.S. El-Kholy , S.A.A. El-Sayed and K. Dhama
  Objective: Three separate experiments were performed to evaluate the biological in vitro effects of two natural antioxidants, resveratrol (RES), cinnamaldehyde (CIN) and their combinations (RES+CIN) on rabbit erythrocytes. Materials and Methods: Suspensions of erythrocytes were divided into 15 groups (each group contains 5 replicates). In three experiments, control group was treated with phosphate buffered saline and dimethyl sulfoxide (DMSO) under the same concentration, while the phytochemical groups in the three experiments were 25, 50, 75 and 100 μM of RES or CIN or their combinations (equal mixture of RES and CIN) added to the control group, respectively and incubated for 3 h at 37°C and exposed to gentle shaking every 15 min. Results: The RES or CIN separately or in combination at different doses enhanced the activities of superoxide dismutase and catalase and improved the concentration of reduced glutathione compared to the control group. Malondialdehyde, protein carbonyl and adenosine triphosphate contents showed linear and quadratic decrease with increasing the concentration of RES or CIN or their combinations. Conclusion: The tested bioactive compounds (RES+CIN) could be helpful in improving the body cells functions without causing hazardous effects and efficiently protected the cells against oxidative injury when used at concentrations up to 100 μM and found to have synergistic effects.
  E.A. Ashour , F.M. Reda and M. Alagawany
  This study evaluated the effect of replacing maize with broken rice (0, 10, 20, 30, 40 and 50 %) on growth performance, feed utilization and carcass traits of growing Japanese quails (1-5 weeks of age). A total of 324 quails (1 week old) were used in a complete randomized design experiment with six treatment groups. Each group was subdivided into three replicates with 18 birds per replicate. Live Body Weight (LBW) and Body Weight Gain (BWG) were significantly (p<0.05) affected by treatments throughout the experiment. The highest values of LBW (189.53g) and BWG (5.70 g) achieved by birds fed broken rice at 20% level during all the experimental periods compared to the other groups. Feed Intake (FI) was significantly (p<0.05 or 0.01) affected by broken rice replacement during all the experimental periods. Feed Conversion Ratio (FCR) was statistically (p<0.05) influenced by broken rice levels through 1-5 weeks of age only. Replacement of corn by broken rice in the diets did not affect (p>0.05) dressing, carcass, giblets, heart, liver and gizzard percentages of meat-type quails as compared to corn-soya diet. Economical efficiency did not affect with the different levels of broken rice throughout the experiment. Based on the present findings, broken rice can be considered a potential substitute of corn up to 50% in meat-type quail diets. Since, it is a by-product of rice processing its composition may vary, studies for determination of metabolizable energy and digestible amino acid contents may allow maximizing its inclusion in quail diets.
  M. Alagawany and Kh. M. Mahrose
  Improving productivity, reducing feed cost or increasing economical efficiency are main challenges in laying hen farms. Thus, the present experiment was conducted to study the effect of different levels of lysine and Total Sulfur Amino Acids (TSAA) on productive performance, egg quality and economical evaluation of Lohmann Brown laying hens. A total numbers of 144 hens aged from 34-50 weeks of age, were randomly divided into 9 experimental groups of 16 hens each. Each group was sub-divided into four replicates (4 hens per each). The experimental design was a 3x3 factorial arrangement with 3 levels of total lysine (0.74, 0.84 and 0.94%) and 3 levels of TSAA (0.67, 0.72 and 0.77%). Lohmann Brown hens consumed different levels of lysine, TSAA and their interaction showed non-significant differences in final body weight and body weight change at the end of experimental period. Feed consumption for hens fed 0.74 and 0.94% lysine significantly increased vs. those received 0.84% lysine diet during the experimental periods (34-38 and 38-42 weeks of age). Feeding different levels of lysine, TSAA and their interaction showed insignificant differences in productive performance criteria during the experiment. Egg quality was not affected by lysine levels except albumen percentage, Unit Surface Shell Weight (USSW) and yolk:albumen at 42 weeks as well as USSW and yolk diameter at 50 weeks of age. Egg market price, net revenue and economical feasibility were affected with different levels of lysine and TSAA, whereas, 0.84 and 0.72% of TSAA recorded the highest economical evaluation values, respectively. It can be conducted that, using 0.84% lysine and 0.72% TSAA was better to get the best productive performance and economical efficiency of Brown Lohmann hens throughout the production period of 18-34 weeks of age.
  F.M. Reda , E.A. Ashour , M. Alagawany and M.E. Abd El- Hack
  The present study was performed to investigate the effect of dietary levels of protein, energy and Lys on growth performance and carcass traits of growing Japanese quails during 1-5 weeks of age. A factorial design 3×2×2 arrangement was performed including three levels of crud protein (CP; 22, 23.5 and 25%), two levels of metabolizable energy (ME; 2900 and 3000 kcal ME kg-1) and two levels of total lysine (Lys; 1.3 and 1.45%). Live Body Weight (LBW) at 3 weeks of age and Body Weight Gain (BWG) during 1-3 weeks of age were significantly (p≤0.01) maximized when chicks were fed 22% CP compared to those received 23.5 and 25% CP. LBW at 3 and 5 weeks of age as well as BWG through 1-3 and 1-5 weeks of age were statistically (p≤0.05) decreased with increasing dietary energy from 2900-3000 kcal ME kg-1 diet. LBW at 3 weeks of age and BWG during 1-3 weeks of age were maximum when chicks were fed 1.45% Lys compared with group received 1.3% Lys level. Interaction between protein and energy levels significantly (p≤0.01) affected LBW at 3 weeks of age and BWG through 1-3 weeks of age. Also, LBW at 5 weeks of age and BWG through 1-5 weeks of age were statistically (p≤0.05) influenced by the interaction between ME and Lys levels. Increasing dietary ME level from 2900 to 3000 caused significant improvements in FCR at all studied ages except period 1-3 weeks of age. The present results did not show any significant effect on all carcass characteristics due to different dietary CP, ME and Lys or their interactions, except carcass percentage was higher in chicks fed diet contained 1.3% Lys. Also, giblet percentage was significantly (p≤0.01) affected by energy levels and the interaction among dietary CP, ME and Lys levels. Moreover, dressing percentage was significantly (p≤0.01) influenced by CP and Lys levels. It can be concluded that, diet formulated in 22% CP, 2900 kcal ME kg-1 and 1.3% Lys can adequately ensure the growth performance in Japanese quails.
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