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Articles by M. Aktaruzzaman
Total Records ( 5 ) for M. Aktaruzzaman
  M. Aktaruzzaman , A.N.M. Fakhruddin , M.A.Z. Chowdhury , Z. Fardous and M.K. Alam
  Accumulation of heavy metals in environmental matrices is a potential risk to living system due to their uptake by plants and subsequent introduction into the food chain. A study was conducted to investigate the heavy metals concentration in soils and leafy vegetables samples along the Dhaka Aricha Road to assess their potential ecological risk. Heavy metals concentration was analyzed by Atomic Absorption Spectroscopy. Concentrations of all the tested heavy metals except Cd in soil samples were below the permissible level. The mean concentration of Cd was found 3.99±1.85 mg kg-1. Concentrations of all the tested heavy metals except Cd and Cr in vegetables samples were lower than recommended level. Mean concentration of Cd and Cr were found 1.00 ± 0.68 mg kg-1 and 2.32±0.84 mg kg-1, respectively. Based on the Potential Ecological Risk Index, Cd posed very high risk to the local ecosystem due to its higher Risk Factor, >320 and based on Transfer Factor of Pb and Cd were found higher accumulator among the tested metals. The results of present study revealed that the bioconcentration of heavy metals along the Dhaka Aricha Road posed high risk to the ecosystem. Considering the Transfer Factor of Cd and Pb it can be suggested that plants and leafy vegetables grow in the soil near Dhaka Aricha Road should not be used as food or feed.
  M. Aktaruzzaman , M.S. Islam , M.M.R. Howlader , M.M. Hossain and M.SD. Islam
 

A CASE OF PLAGIARISM

Pharmacologia editorial office received a complaint from Batoul Sadat Haerian, Pharmacogenomics Lab, Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia about a plagiarism of her paper published in Pharmacologia Volume 6 Number 5: 149-159, 2015.

On the receipt of her complaint, the case forwarded to the Ethics Committee of the Pharmacologia. As per the report of the Ethics Committee, article entitled “Role of KCN11, Gene Polymorphism and Risk of Type 2 Diabetes Mellitus” authored by M. Akhtaruzzaman, M.S.Islam, M.M.R.Howlader, M.M.hossain and M.SD. Islam published in Pharmacologia Volume 6 Number 5: 149-159, 2015 contains substantial sections of text that have been taken verbatim from earlier publication without clear and nambiguous attribution. The corresponding author of this article is M.Akhtaruzzaman, Pharmacogenomics Lab., Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

Pharmacologia considers misappropriation of intellectual property and duplication of text from other authors or publications without clear and unambiguous attribution totally unacceptable.

Plagiarism is a violation of copyright and a serious breach of scientific ethics. The Editors and Publisher have agreed to officially retract this article.

Pharmacologia is highly thankful to Batoul Sadat Haerian for pointing out this plagiarism.

Detail of the article from which M. Akhtaruzzaman has copied text:
Polin Haghvirdizadeh, Zahurin Mohamed, Nor Azizan Abdullah, Pantea Haghvirdizadeh, Monir Sadat Haerian and Batoul Sadat Haerian,“KCN 11: Genetic Polymorphism and Risk of Diabetes Mellitus” Journal of Diabetes Research, 908-152, 2014.

Final Decision: Ethics Committee strongly condemns the act of plagiarism committed by M.Akhtaruzzaman and suggested to retract the paper immediately and also suggested to communicate this to the higher authorities of the corresponding author for suitable action according to their rules and regulations.

  M. Aktaruzzaman , M. S. Islam and M. M.R. Howlader
  Background and Objectives: This study aimed to evaluate the efficacy of ivermectin, levamisole HCl and albendazole against gastrointestinal nematodes on the basis of body weight of goats and hematological parameters like TEC, Hb, PCV, ESR and TLC in naturally infected goats of Government Goat Development Farm, Sylhet, Bangladesh. Methodology: The study included 50 black Bengal breed of which thirty were naturally infected and twenty of 13-15 month old irrespective of sex were randomly selected for this experiment on the basis of their weight and egg count and randomly divided into four equal groups A, B, C and D where each group consisted of 5 goats and goats of group D were kept as control group. One injectable ivermectin (200 μg kg-1 b.wt., S/C) preparations and two solid levamisole Hcl and albendazole (7.5 mg kg-1 b.wt., orally) preparations were used for positive control of group A, B and C. Before trials (day 0), blood samples and initial body weight were recorded. During the study period, the fecal and blood samples were collected and examined on 7th, 14th, 21st and 28th day using McMaster fecal egg counting method. Results: The results of the comparative efficacies of anthelmintic of ivermectin were 83.25%, followed by levamisole HCl 94.53% and albendazole 86.12%. After treatment, TEC, Hb and PCV were increased significantly (p<0.01 and p>0.05) in goats but ESR and TLC were decreased significantly (p<0.05 and p>0.01) in all treated goat and body weight was increased significantly (p<0.01) on day 28. Conclusion: The findings of the present study reveal that Ivermectin (A-mectin, injectable formulation), Levamisole (Levavet) and Albendazole (Almex-Vet) are effective for the reduction of EPG (eggs per gram) of gastrointestinal nematodes. Additional detailed studies are required to clarify the current status of the efficacy of the anthelmintic widely used in different agro ecologies, animal species and livestock management systems in Bangladesh.
  T. Sultana , M.S. Islam , M. Aktaruzzaman , F. Begum , M.K. Hossain , N.S. Lucky and M.M.R. Howlader
  Background: This study aimed to evaluate the efficacy of fenbendazole and piperazine citrate against ascariasis in naturally infected calves of Sylhet Dairy Farm, Sylhet, Bangladesh. The study included 84 calves of which 40 were naturally infected and randomly selected 20 on the basis of their weight and egg count. Twenty calves of 1-8 month old irrespective of sex infested with ascariasis were selected for this experiment and randomly divided into four equal groups (group A, B, C and D) where each group consisted of 5 calves and calves of group D were kept as control group. Two fenbendazole (7.5 mg kg-1 b.wt., orally) preparations (Globe Pharmaceuticals Ltd. and Techno drugs Ltd., Bangladesh) and piperazine citrate (220 mg kg-1 b.wt., orally) preparations (Ethical drugs Ltd., Bangladesh) were used for positive control of ascariasis as group A, B and C. Calves of group D was kept as control without giving any treatment. Objective: The present investigation was aimed to evaluate the effects of modern anthelmintics Fenvet® (Fenbendazole), Peraclear® (Fenbendazole) and Therazin® (Piperazine citrate) against ascariasis in calves irrespective to the species involved and their effects on the basis of EPG (eggs per gram) count, body weight of calves and hematological parameters like Total Erythrocyte Count (TEC), Hemoglobin (Hb%), Packed Cell Volume (PCV), Erythrocyte Sedimentation Rate (ESR) and Total Leukocyte Count (TLC) were also included in this investigation. Results: Before trials (day 0), total egg count, blood samples and initial body weight were recorded. During the study period the fecal and blood samples were collected directly from rectum on 7th, 14th, 21st and 28th day and examined using McMaster fecal egg counting method. Body weights were recorded on day 0 and day 28 following the treatments. The results of the comparative efficacies of different anthelmintic of fenbendazole were 95.50 and 95.58%, followed by piperazine citrate 97.27%, respectively. McMaster fecal egg counting method discloses the percentage of prevalence of ascariasis 35.71% (1-2 months), 24.00% (3-4 months), 21.74% (5-6 months) and 18.18% (7-8 months), respectively. After treatment with fenbendazole and piperazine citrate, Total Erythrocyte Count (TEC), Hemoglobin (Hb) content and Packed Cell Volume (PCV) were increased significantly (p<0.01 and p>0.05) in calves but Erythrocyte Sedimentation Rate (ESR) and Total Leukocyte Count (TLC) were decreased significantly (p<0.05 and p>0.01) in all treated calves and body weight was increased significantly (p<0.01) on day 28. The farm management practices along with results of the present study revealed the efficacy of multiple anthelmintic against gastrointestinal nematodes in calves. Additional detailed studies are required to clarify the current status of the efficacy of the anthelmintic widely used in different agro ecologies, animal species and livestock management systems in Bangladesh.
  S. Khanam , M.S. Islam , M. Aktaruzzaman , M.M. Hossain , M.K. Hossain , M.A. Mamun , M. Noor and M.M.R. Howlader
  The study was conducted to evaluate the efficacies of three different commercial anthelmintic containing triclabendazole and nitroxynil against fascioliasis in goat for a period of 28 days by using 20 goats. Among hundred goats, twenty goats were selected for this study which was suffering from liver fluke (Fasciola gigantica) infection and they were marked at the neck by tag. Twenty goats were randomly divided into four groups (A, B, C and D), where each group comprising of five goats. Goats of group A were treated with tablet fasinex (triclabendazole, Novartis Ltd, Bangladesh) orally at the dose rate of 12 mg kg–1 b.wt., group B were treated with acinex (triclabendazole, ACI Ltd, Bangladesh) orally at the dose rate of 12 mg kg–1 b.wt. and group C were treated with nitronex injection (nitroxynil, Renata Ltd, Bangladesh) subcutaneously at the dose rate of 10 mg kg–1 b.wt., Goats of group D was kept as infected control group without giving any treatment. A significant (p<0.01 and p>0.05) reduction of Egg Per Gram (EPG) count was found on 7th, 14th, 21st and 28th days of treated goats of group A, B and C respectively. The EPG count of control group were significantly (p<0.01 and p>0.05) increased 7 day onwards up to experimental period. Reduction of mean EPG on 7th, 14th, 21st and 28th day after treatment in group A, B and C were 81.48, 81.25 and 83.04%, respectively, whereas, in control group the mean EPG were 22.43%. Of the hematological parameters, TEC, Hb and PCV values were lower on day 0 but turned to increase (p<0.01 and p>0.05) on day 28 of the study. On the other hand, ESR and TLC were higher before treatment (day 0) but decreased significantly (p<0.01 and p>0.05) on day 28. The body weight was increased significantly (p<0.01 and p>0.05) after treatments in group A, B and C respectively except untreated control group D. This result may indicate that three different commercial anthelmintic contain triclabendazole and nitroxynil against fascioliasis in goat and nitroxynil have higher efficacies on Egg Per Gram (EPG), hematological parameters and body weight against fascioliasis in goat. Additional detailed studies are required to clarify the current status of the efficacy of the anthelmintic widely used in different agro ecologies, animal species and livestock management systems in Bangladesh.
 
 
 
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