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Articles by M. Sridevi
Total Records ( 3 ) for M. Sridevi
  M. Sridevi , G. Chandramohan and K.V. Pugalendi
  In this study, the protective effect of alcoholic leaf extract of Solanum surattense on blood glucose and redox status in streptozotocin (STZ)-induced diabetic rats has been evaluated. Diabetes was induced in adult male albino Wistar rats weighing 180-200 g, by the administration of STZ (40 mg kg-1 body weight) intraperitoneally. The diabetic rats showed elevated levels of blood glucose and a significant decrease in plasma insulin levels. The increased levels of lipid peroxidation markers such as thiobarbituric acid reactive substances (TBARS), conjugated dienes (CD) and lipid hydroperoxides (LOOH) were observed in diabetic rats. The activities of enzymatic antioxidants (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glucose 6-phosphate dehydrogenase) and the levels of non-enzymatic antioxidants, (reduced glutathione (GSH) and vitamin C) decreased, whereas, vitamin E increased in the erythrocytes of diabetic rats. Plasma hepatic marker enzymes also increased in STZ-diabetic rats. Oral administration of S. surattense leaf extract (100 mg kg-1 b.wt.) reversed these parameters towards normalcy. Thus, our results indicate that the S. surattense leaf extract possesses antihyperglycemic, antilipidperoxidative and hepatoprotective and antioxidant potential in diabetic rats.
  M. Sridevi and K.V. Mallaiah
  The ability of twenty six Rhizobium strains, isolated from root nodules of leguminous crop, Sesbania sesban (L.) Merr. were tested for their production of extracellular polysaccharides (EPS) in Yeast Extract Mannitol (YEM) medium. Among the twenty six strains, maximum amount of EPS was produced by Rhizobium SS5 strain (3900 μg mL-1). Both growth and EPS production started simultaneously, but the EPS production was maximum in the stationary phase of growth (48 h). The EPS production was maximum, when the medium was supplemented with galactose (2%), sodium nitrate (0.1%) and Ca-pantothenate (1 μg mL-1), which was accompanied by a great increase in the production compared to the control. The EPS contained galactose, glucose, xylose, rhamnose and raffinose, which were identified by paper as well as gas liquid chromatography.
  M. Sridevi and K.V. Mallaiah
  Rhizobium strains isolated from root (Sesbania procumbens) and stem nodules (S. rostrata and S. procumbens) of Sesbania species were tested for their ability to produce Indole-3-Acetic Acid (IAA). The isolates produced maximum amount of IAA in culture after 72 h of incubation and at 3.0 mg mL 1 L-tryptophan concentration. The effect of different carbon and nitrogen sources on IAA production was also studied and it revealed that, glucose (1%) and potassium nitrate (0.1%) were found to be best promoters for IAA production. An addition of EDTA (0.1 g mL 1) significantly increased the IAA production over controls and the production was maximum at 0.2 g mL 1 EDTA concentration. Among the three isolates, maximum amount of IAA was produced by Rhizobium isolate from stem nodule of S. procumbens. The IAA was extracted, purified and identified by thin layer chromatography.
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