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Articles by M. Shah Alam Bhuiyan
Total Records ( 5 ) for M. Shah Alam Bhuiyan
  Golam Sadik , M. A. Gafur , M. Shah Alam Bhuiyan , A. H. M. Khurshid Alam , M. Helal U. Biswas , Parvez Hassan , Abdul Mannan , M. Omar Faruk Khan and A. K. A. Chowdhury
  The ethanolic extract of Pergularia daemia and its steroidal fraction were studied for antifertility activity. Both the ethanol extract and the steroidal fraction showed significant antifertility activity in the pre-implantation stage in female mice. The ethanol extract also showed late abortifacient activity
  M. Helal Uddin Biswas , A. R. M. Ruhul Amin , M. Shah Alam Bhuiyan , M. A. Rashid , M. Ahmed and M. A. Islam
  A Monocillium species isolated from a soil sample which grown optimally in Czapek`s dox broth (acidic) medium yielded the metabolic compound HB identified as a mixture of novel compounds, Monocillinols A and B. Antibacterial activities of the compound were observed against fifteen Gram positive and Gram negative pathogenic organisms. The compound showed significant antibacterial activities against all pathogenic organisms tested except Gram negative Shigella sonnei. The minimum inhibitory concentration (MIC) values of the compound were determined against Bacillus subtilis, Sarcina lutea, Staphylococcus aureus, Shigella dysenteriae, Escherichia coli and Salmonella typhi and found to be 128, 256, 128, 128, 128 and 128 g/ml, respectively.
  Anwarul Islam , Abu Sayeed , Md. Anwar-Ul Islam , G. R. M. Astaq Mohal Khan , M. Helal U. Biswas and M. Shah Alam Bhuiyan
  The research work was conducted to investigate the antimicrobial and cytotoxic evaluation of a flavonone. The flavonone, 5-methoxy-7-hydroxy flavonone (1), has been isolated from the leaves extract of Zanthoxylum budrunga and its structure was established on the basis of structural evidence. This is the first report of its occurrence from the plant. The compound (1) showed significant antimicrobial activity against a number of pathogenic bacteria and fungi. The minimum inhibitory concentration (MIC) of the compound (1) was found to be 16μg ml‾1 against Staphylococcus aureus. The compound showed prominent cytotoxic activity the LC50 and LC90 values of the compound (1) were found to be 16.24 and 56.56μg ml‾1, respectively.
  Md. Golam Sadik , M. A. Gafur , M. Shah Alam Bhuiyan , M. Motiur Rahman and Helal U. Biswas
  The ethanol extract of Pergularia daemia and its steroidal fraction are reported to have antifertility activity. In this work we studied the alkaloidal fraction of the ethanol extract to observe its antifertility activity. Oral administration of the alkaloidal fraction at a dose of 200mg kg‾1 body weight showed a significant activity in preimplantation stage of female mice. The activity of the alkaloidal fraction, when compared with the steroidal fraction, was found to be more pronounced since the former inhibited not only the fertility of the female mice but also took short period to return the oestrous cycle to normal, with in 4 to 6 days of drug treatment while steroidal fraction treated mice returned to normal within 6 to 8 days.
  Anwarul Islam , Abu Sayeed , M. Shah Alam Bhuiyan , M. Ashik Mosaddik G. , R. M. Astaq Mohal , M. A. Rashid and Md. Anwar-UI Islam
  Three terpenes lup-20 (29)-en-3-one (ZB-1), 11 , 13-dihydro-1epireynosin (ZB-2) and tetracyclic diterpenol-15-cinnamate (ZB-3) were isolated from the bark of the plant Zanthoxylum budrunga and were screened against some pathogenic bacteria and fungi. They were found significant in vitro antibacterial and antifungal. The zones of inhibition produced by the pure compounds were laid between 9 mm to 23 mm. The MIC values of the three isolated compounds were also determined against four test organisms (107 cells/ml) and were found to be effective between 16 μg/ml to 128 μg/ml.
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