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Articles by M. Saifur Rahman
Total Records ( 3 ) for M. Saifur Rahman
  M.J. Islam , A.K.M.M. Hossain , F. Khanam , U.K. Majumder , M.M. Rahman and M. Saifur Rahman
  To study the effect of mulching and fertilizer management practices on the growth and yield of garlic, an experiment was conducted using three kinds of mulches viz., black polyethylene, straw and water-hyacinth with a control and three types of fertilizer management practices viz., cow dung (F1), urea + TSP + MP (F2) and urea + TSP + MP + cow dung (F3) were compared with no fertilizer/manure. Plants grown under black polyethylene, water hyacinth and straw mulches were produced the yields of 5.80, 5.70 and 5.48 t ha-1, respectively which were 39, 36.6 and 31.41% higher than the control (4.17 t ha-1). The effect of black polyethylene and water hyacinth mulch were almost similar on the growth and yield of garlic. On the other hand, the crops growing with urea + TSP + MP and urea + TSP + MP + cow dung and only cow dung gave yields of 6.36, 6.03 and 5.23 t ha-1, respectively which showed about 80.68, 71.30 and 48.57% increased over the control (3.52 t ha-1). The interaction effects of mulching and fertilizers did not exhibit significant variations. Though the application of black polyethylene mulch is somewhat hazardous, if it is possible to use the water hyacinth and black polyethylene mulch along with F2 and F3 were suitable for increasing production.
  M. Saiful Islam , M. Badrul Alam , Ronok Zahan , G.C. Sarker , N.S. Chowdhury , M. Maruf Khan , Mahedi Hasan , M. Saifur Rahman , M.A. Mosaddik , Mele Jesmin and M. Ekramul Haque
  The present study was designed to investigate the antioxidant and anti neoplastic activities of Ocimum sanctum Linn. (OS) leaves. Antioxidant potential of the OS extract was evaluated in vitro by DPPH (1, 1diphenyl-2-picrylhydrazyl) and NO (Nitric Oxide) scavenging assay and reducing power assay method. OS extract showed prominent scavenging activity in all the methods with IC50 value of 16.39±0.31 and 16.20±0.33 μg mL-1 for DPPH and NO assay method, respectively. In reducing power assay, OS extract also showed significant (p<0.001) activity. In addition, total phenolic and flavonoid content and total antioxidant capacity were also determined. The anti neoplastic effect of the leaves of OS against Ehrlich Ascites Carcinoma (EAC) in mice at the doses of 50 mg kg-1 body weight intraperitoneally. Significant (p<0.001) increases of survival times 33±1.81 days for crude extract of the (50 mg kg-1) treated tumor bearing mice were confirmed with respect to the control group (20±0.12 days). Hematological studies reveal that the Heamoglobin (Hb) content was decreased in EAC treated mice whereas restoration to near normal levels was observed in extract treated animals. There was a significant (p<0.001) decrease in RBC count and increase in WBC counts in extract/fraction treated animals when compared to EAC treated animals. From the result it was showed that the extract has significant antioxidant as well as anti neoplastic activity.
  M. Badrul Alam , M. Saifur Rahman , M. Hasan , M. Maruf Khan , Kamrun Nahar and Sheema Sultana
  Dillenia indica Linn. (Dilleniaceae) is widely used as food and reputed in the folk medicine of Bangladesh and India in particular, to relieve pain associated with gastrointestinal disturbance. Methanolic extract of the bark of Dillenia indica Linn. (MDI) was subjected to evaluate for its analgesic and antioxidant properties. The analgesic activity of MDI (200 and 400 mg kg-1 b.wt. p.o.) was determined for its central and peripheral pharmacological actions using hotplate as well as tail immersion method and acetic acid-induced writhing test with formalin induced pain in mice, respectively. To evaluate antioxidant potential of MDI, total antioxidant activity, scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical as well as total Reactive Oxygen Species (ROS) and assessment of reducing power were used. The extract, at the dose of 200 and 400 mg kg-1, produced a significant (p<0.05) increase in pain threshold in hotplate and tail immersion methods whereas significantly (p<0.05) reduced the writhing caused by acetic acid and the number of licks induced by formalin in a dose dependent manner. In DPPH and total ROS scavenging method, MDI showed good antioxidant potentiality with the IC50 value of 12.32±0.16 and 34.72±0.48 μg mL-1, respectively with a good reducing power. The findings of the study suggested that MDI has strong analgesic and antioxidant effects, conforming the traditional use of this plant for pain alleviation to its antioxidant potentiality.
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