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Articles by M. Mahmoudi
Total Records ( 3 ) for M. Mahmoudi
  M.R. Gohari , M. Mahmoudi , K. Mohammed , Y. Pasha and R. Khodabakhshi
  This study designed and carried out to determine the disease-free survival of breast cancer patients after surgery and to assess its associated factors. The variability in effect of prognostic factors over time was also assessed. For this purpose one hundred seventeen women with breast cancer operated on at three hospitals in Tehran, Iran between 1990 and 2003 were enrolled in study. Since the occurrences of successive metastases in any patient are correlated and the occurrence of one metastasis may make further events more or less likely we used a Stratified Markov model to account for within-subject correlation in event times. This model stratifies data by event so that the baseline hazard is allowed to vary with each metastasis. In this model effect of covariates on the hazard of event is also estimated in each stratum, separately. The variables of age at time of surgery, number of positive lymph nodes, histologic grade, size of tumor, ER status, P53 and Her2 were considered in the model. Median follow up time for patients in study was 26 months after surgery. During the follow up time 44(38%) patients developed metastasis. 20(45%) of those experienced the second metastasis. The median disease-free survival for patients in study was 49.6 month and the median time to experience the second metastasis was 22.5 month. Risk of occurrence of a metastasis in the first year after mastectomy was 12%. Up to the second and fifth years risk of experience a metastasis was 32 and 69%, respectively. The rate of metastasis in our study was higher than some other countries. One reason for highly rate of relapse in patients is the fact that patients sought medical attention when the disease has reached an advanced stage. Stratified Markov model showed that the effect of prognostic factors was different for the first and the second metastasis. Size of tumor and number of positive lymph nodes had a significant effect on the risk of first metastasis. While tumor size was the only factor that affected hazard of the second metastasis. One possible reason for this finding is that the effect of these factors was mixed with the effect of time to first metastasis and we can`t separate them in analysis of the second time.
  A.R. Bahonar , M. Azizzadeh , M.A. Stevenson , M. Vojgani and M. Mahmoudi
  We conducted a retrospective cohort study to investigate factors influencing the reproductive performance of dairy cattle in Khorosan Razavi province, Iran. Ten dairy herds, located within a 45 km radius of the city of Mashhad in Khorosan Razavi province took part in the study. Complete lactation records were collected for cows that calved between 21st March 2006 and 20th March 2007. Each cow was followed until the end of the study on 21st October 2007 or until the date of leaving the herd, either by culling, sale, or death. Median days open was 123 days (range 28-430 days). Cox proportional hazard models with and without a herd level frailty term were used to identify and quantify the effect of factors influencing days open. Parity and the presence of uterine infection, cystic ovarian disease, mastitis and lameness were positively associated with days open. The proportion of variance explained at the herd level was 0.33% suggesting that the herds that participated in this study were relatively homogenous in the distribution of unmeasured herd-level factors influencing days open. This study has provided starting point for defining benchmark estimates of reproductive performance in dairy herds in this area of Iran. Quantifying the effect of disease on reproductive performance provides a means for ranking disorders in terms of their effect on fertility, allowing intervention strategies designed to optimise herd health and production to be further refined.
  G.R. Moosavi , K. Naddafi , A. Mesdaghinia , F. Vaezi and M. Mahmoudi
  The liquid-gas absorption is by far the most applied system for odor control. A bench scale packed bed scrubber was used to evaluate of H2S removal as the odorant model compound using three chemical oxidants of NaClO, H2O2 and KMnO4 at various operation conditions. Results showed that more than 99.5% of the H2S was removed from the inlet air in the EBCTs of 3 to 35 s and H2S concentrations in the range of 30 to 300 ppmv. Also, the pressure drop across the bed of the reactor increased from 1.5 to 13.1 cm H2O m-1 for the superficial air velocities in the range of 1.2 to 14 m min-1 which a linear relationship was observed between pressure drop and superficial air velocities.
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