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Articles by M. Izadi
Total Records ( 3 ) for M. Izadi
  M. Parsa , S.N. Najafi , N. Jonaidi Jafari , M. Mohraz , A. Ghavamzadeh , B. Bahar , M. Izadi , M.H. Radfar and H. Ghofrani
  The present study was designed to determine diagnostic value of IL-6 and TNF-α in patients with fever and neutropenia. This is a prospective study of 133 patients admitted to two university hospital in Tehran, Iran with fever and neutropenia. Patients were divided two groups as low risk and high-risk groups. Cytokines level compared with Mann-Whitney test in study groups of patients and ROC curves used to determine best cut-off points level for cytokines discriminating risk groups. Mean age of patients was 26.8±2.5 years and 7.5% of patients allocated in low risk group. The mean IL-6 and TNF-α serum level below 17 pg mL-1 was defined as best cut-off point determining low risk group patients with sensitivity and specificity of 70 and 67.5% respectively. However, we cannot define a statistically significant cut-off point for TNF-α to use as a diagnostic test. 13.5% of patients of our study have positive blood cultures (6% gram-negative, 6% gram- positive, 1.5% fungi), but no statistical difference had found in serum IL-6 and TNF-α levels in blood culture groups. Despite our findings about IL-6 diagnostic value in neutropenic patients with fever and its advantages in discriminating risk groups of patients it seem necessary to design a randomized controlled trial before use of this marker.
  M.H. Shirazi , R. Ranjbar , S. Eshraghi , G. Sadeghi , N. Jonaidi , N. Bazzaz , M. Izadi and N. Sadeghifard
  In the present study, the in vitro inhibitory effects of G. glabra extract against the growth of Salmonella typhi, S. paratyphi B, Shigella sonnei, S. flexneri and enterotoxigenic E. coli (ETEC E. coli) was investigated using well and disc diffusion method. Shigella spp. and enterotoxigenic E. coli but Salmonella paratyphiB showed no susceptibility to liquorice with concentrations lower than 7.5%, however all tested bacterial strains exhibited susceptibility to high concentration of liquorice. Results obtained from present study showed that G. glabra can be considered as an alternative herbal antibacterial agent against the bacterial strains tested.
  G.R. Irajian , M. Nassaji , R. Ranjbar , A. Beheshti , R. Ghorbani , S. Salmanzadeh-Ahrabi , S. Ramazanzadeh , E. Moshiri , A. Karami , M.J. Hosseini , N. Bazzaz , N. Jonaidi Jafari and M. Izadi
  In this study, directly observed short course therapy (DOTS) was implemented to control tuberculosis in a camp in Iran. First, one study had been conducted in 1996 (before DOTS implementation) as active case finding then DOTS have been implemented in 1997. Another study was carried out in 2004 for evaluation of the effects of DOTS. In the first study, 16 patients with pulmonary TB (50% smear positive) were detected. During the years of DOTS implementation, the number of TB cases decreased significantly. In the second study, no pulmonary TB was detected. Our experience showed that DOTS significantly and effectively decreases TB in refugees and leads to a high cure rate and prevents death.
 
 
 
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