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Articles by M. Gbeassor
Total Records ( 3 ) for M. Gbeassor
  J. Koudou , A.W. Etou Ossibi , K. Aklikokou , A.A. Abena , M. Gbeassor and J.M. Bessiere
  The composition of the essential oil from the fruit seeds of Monodora myristica Gaertn. (Annonaceae) was studied by capillary gas chromatography. The analysis using a combination of retention indices and combined Gas Chromatography/Mass Spectrometry (GC/MS) led to the identification of 30 components. The oil contains mainly monoterpenoids (93.2%) out of which 77.4% are monoterpene hydrocarbons and some sesquiterpenoids (5.8%) The major constituents were α-phellandrene (34.4%) and p-cymene (22.2%). The essential oil effects on the cardiovascular system were studied by recording the amplitude and frequency of the frog isolated heart contractions and by recording arterial blood pressure variations of the guinea pig. At the dose of 40, 80 and 120 μL kg-1 the essential oil induced a hypotensive effect on the blood pressure and at the dose of 0.01-0.05%. It reduced significantly the cardiac contractions of the isolated heart; however at 0.06% it totally stopped the cardiac contractions. Both these effects conducted in the present study could contribute to the anti hypertensive activity of the Monodora myristica essential oil.
  B. Bakoma , K. Eklu-Gadegkeku , A. Agbonon , K. Aklikokou , E. Bassene and M. Gbeassor
  The root of B. ferruginea is traditionnally used as a treatment for type 2 diabetes. The present study was investigated to evaluate the preventive effect of B. ferruginea on some markers of metabolic syndrome in type 2 diabetes (hyperlipidemia, glucose intolerance, obesity and oxidative stress) induced by high fructose and fat diet in male Wistar rat. The rats received fructose diet (10 mL kg-1 per day) during 42 days; at the 15th day to the 42nd day 15 min before, they received distilled water for high fructose diet group, metformine 100 mg kg-1 per day or extract 125 and 250 mg kg-1 per day for treatment group. The control group received only distilled water during the experiment. After 6 weeks of experiment, fasting blood glucose, liver MDA level, body weight gain, intra abdominal grease, serum triglyceride (TG) and total cholesterol levels in treated groups were significant lower than that of high- fructose diet group. However, rats in treated group were not found to have a significant change of blood HDL Cholesterol level. In the oral glucose tolerance test, rats in treated group had a significantly reduced blood glucose concentration during 180 min after glucose load, indicating that B. ferruginea root improved glucose tolerance. In conclusion, our plant can prevent metabolic syndrome induced by high fructose diet.
  N. Okiemy-Andissa , M.L. Miguel , A.W. Etou , J.M.Ouamba , M. Gbeassor and A.A. Abena
  Analgesic effect of aqueous and hydroalcoholic extracts of aeral parts of Hyptis suavolens, Nauclea latifolia and Ocimum gratissimum, three plants used in congolese folk medicine in pain, were tested on acetic acid and hot plate tests. All extracts manifest analgesic effect on the two models used. The more active was the hydroalcoholic extract of Ocimum gratissimum which is not antagonized by naloxone and could potentiate analgesic effect of paracetamol.
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