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Articles by M. Ashik Mosaddik
Total Records ( 5 ) for M. Ashik Mosaddik
  M. Saidul Islam , M. Akhter Farooque , M.A.K. Bodruddoza , M. Ashik Mosaddik and M. Shahidul Alam
  Mixed ligand transition metal complexes of Cu+2, Ni+2 and Co+2 ions with Schiff base ligands (SB-1 & SB-2) derived from the condensation of O-hydroxy benzaldehyde with amino phenols and nitrogen donor amine bases, e.g. ethylenediamine, 2-aminopyridine, O-Phenylenediamine or thiocyanate have been synthesized. Their conventional physical and chemical analyses have been done. Their anti-bacterial and anti-fungal activity have been evaluated including toxicological studies.
  M. Saidul Islam , M. Akhter Farooque , M.A.K. Bodruddoza , M. Ashik Mosaddik and M. Shahidul Alam
  Mixed ligand transition metal complexes of Cu+2, Ni+2 and Co+2 ions with Schiff base ligands (SB-1 and SB-2) derived from the condensation of o-hydroxybenzaldehyde with amino phenols and nitrogen donor amine bases, e.g. ethylenediamine, 2-aminopyridine, o-phenylenediamine or thiocyanate have been synthesized. Their conventional physical and chemical analysis had been done. Their anti-bacterial and anti-fungal activity had been evaluated including toxicological studies.
  Rezina Laz , Md. Abdul Hye Khan , M. Ashik Mosaddik , M. A. Samad and K. Faisal Alam
  Multiple drug resistant Escherichia coli isolated from Rajshahi metropolis, which were resistant against ampicillin, tetracycline, chloramphenicol, erythromycin, kanamycin, streptomycin and nalidixic acid at 90, 70, 45, 45, 35, 30 and 10% respectively. Moreover, plasmid DNAs having molecular weight of 5.0 to 8.1 MD and molecular size of 28.4 to 39.0 kb has been isolated from these drug resistant mutants.
  Shahrear Ahmad , M.N. Amin and M. Ashik Mosaddik
  Phytochemical screening and alkaloid estimation of in vitro and field grown plants of R. serpentina has been investigated. Under the phytochemical screening moisture content (at 45 and 105oC), biomass yield and alkaloid content in vitro and field grown plant materials were determined. At 45oC in vitro plant materials (leaf, root and callus) have higher moisture content compared with field grown (3 years mature plants) plant materials (leaf and root). But opposite result was observed at 105oC. Percent yield of crude plant extract (Biomass yield) of in vitro plant materials was higher than that of field grown plant materials. The percentage of alkaloid for in vitro plant materials was 1.17% in callus, 0.98% in root and 0.49% in leaf, respectively. On the other hand it was found that the field grown plant materials were 0.71% in leaf and 1.43% in root, respectively.
  M. Abdul Alim Al-Bari , Alam Khan , M. Robiul Islam , M. Kudrat-E-Zahan , M.M. Sazedur Rahman , M. Anwar Ul Islam and M. Ashik Mosaddik
  The aim of the present study was to investigate the antimicrobial activities of ethyl acetate extracts against Gram-positive and Gram-negative bacteria and fungi. An attempt has been made to investigate the indigenous drugs of choice in infectious diseases for mitigation of suffering of the vast masses of humanity. The organism, Streptomyces bangladeshiensis was isolated from a soil sample collected from Natore, Bangladesh at the depth of 0.75 m using crowded plate technique. The maximum secretion of metabolites from the strain was found at the 7th day of incubation in Czapek Dox broth (alkaline pH 8.5) medium at 32.5°C by maintaining the physicochemical factors in optimum level for the culture. In vitro antimicrobial susceptibility was determined as per National Committee for Clinical Laboratory Standards guidelines and serial dilution technique for the determination of Minimum Inhibitory Concentration (MIC) of extracts. Ethyl acetate extract from a new actinomycetes, Streptomyces bangladeshiensis, showed good antibacterial and antifungal activities against a total of 14 bacteria (5 gram positive plus 9 gram negative) and 8 fungi. The Minimum Inhibitory Concentrations (MIC) were determined and found to be 16 μg mL-1 against Bacillus subtilis, Staphylococcus aureus, Shigella dysenteriae and Aspergillus flavus while 32 μg mL-1 against Salmonella typhi, Candida albicans and Aspergillus niger. Present data shows that all the pathogenic microorganisms (Gram positive and negative bacteria and fungi) showed a substantial sensitivity towards the crude extract. But further work is necessary in order to establish the individual antibiotics present of this isolated compound.
 
 
 
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