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Articles by Lisa M. Brosseau
Total Records ( 2 ) for Lisa M. Brosseau
  John W. Cherrie , Lisa M. Brosseau , Alastair Hay and Kenneth Donaldson
  Exposure to low-toxicity dusts, which have previously been viewed as ‘nuisance dusts’, can cause chronic obstructive pulmonary disease or other nonmalignant respiratory disease. In Britain, the ‘de facto’ airborne exposure limits for these dusts have remained unchanged for >30 years; currently, they are 10mg m-3 for inhalable dust and 4mg m-3 for respirable dust. During this time, exposures in industry have decreased and although in the past, many occupational dust exposures may have exceeded these limits, today this is less likely. However, there is good evidence from epidemiology and toxicology studies that current dust exposures may still present a risk to workers and that for some of those who are affected, there are devastating health consequences. Numerous researchers and others have drawn attention to the necessity to control dust exposures to levels lower than are currently accepted in Britain. It is proposed that until regulators agree on the safe occupational exposure limits for low-toxicity dusts, health and safety professionals should consider 1mg m-3 of respirable dusts as a more appropriate guideline than the value of 4mg m-3 currently used in Britain.
  Ronald L. Pearson , Perry W. Logan , Anita M. Kore , Constance M. Strom , Lisa M. Brosseau and Richard L. Kingston
  Previous studies have suggested a potential risk to healthcare workers applying isocyanate-containing casts, but the authors reached their conclusions based on immunological or clinical pulmonology test results alone. We designed a study to assess potential exposure to methylene diphenyl diisocyanate (MDI) among medical personnel applying orthopedic casts using two different application methods. Air, dermal, surface, and glove permeation sampling methods were combined with urinary biomonitoring to assess the overall risk of occupational asthma to workers handling these materials. No MDI was detected in any of the personal and area air samples obtained. No glove permeation of MDI was detected. A small proportion of surface (3/45) and dermal wipe (1/60) samples were positive for MDI, but were all from inexperienced technicians. Urinary metabolites of MDI [methylenedianiline (MDA)] were detected in three of six study participants prior to both a ‘dry’ and ‘wet’ application method, five of six after the dry method, and three of six after the wet method. All MDA results were below levels noted in worker or general populations. Our conclusion is that the risk of MDI exposure is small, but unquantifiable. Because there is some potential risk of dermal exposure, medical personnel are instructed to wear a minimum of 5-mil-thick (5 mil = 0.005 inches) nitrile gloves and avoid contact to unprotected skin. This could include gauntlets, long sleeves, and/or a laboratory coat.
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