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Articles by Liping Zhang
Total Records ( 4 ) for Liping Zhang
  Liping Zhang and Haibo Jiang
  In this study, we investigate the problem of impulsive exponential consensus of multi-agent systems, where each agent is represented by an identical T-S fuzzy model. Firstly, a fuzzy impulsive control protocol is designed for networks with fixed topology based on the local information of agents. Then sufficient conditions in terms of linear matrix equalities are given to guarantee the exponential consensus of the multi-agent fuzzy systems. Numerical simulations show the effectiveness of our theoretical results.
  Jianlei Jia and Liping Zhang
  Completion of the human genome project marked the life sciences had entered the post-genomics and as an important element in the post-genome, proteomics had already gone deep into the field of life sciences and medicine. In recent years, proteomics technology developed sharply. In this study, the concept of proteomics, the background was introduced and summarized the technical route and progress of proteomics.
  Jing Wang , Liping Zhang , Jianping Wu , Jianlei Jia and Qiang Ding
  Association between lambing performance (single lamb and twins) and reproductive hormones has been explored. Twenty four ewes divided into 4 groups of each 6 individuals were sampled according to the number of lambs in two breeds (Mongolian ewes and Poll Dorset ewes) blood samples from each individual ewe were collected at the three periods: estrus (day 0) estrus (day 11) and post-partum anoestrus. All the seven hormones concentration of the Poll Dorset ewes was higher than that of the Mongolian ewes in the three periods. And the hormones secretion shown different patterns in two breeds. Five hormones concentrations of ewes with twins were higher than that of ewes with single lamb, the reverse situation found in MT and T concentration even a few of them were statistically significant (p<0.05) at the three periods. Finally, the highly positive and negative significant correlations between hormones were detected, this relationship also shown the differences in two breeds.
  Liping Zhang , Ying Zhang and Kelly G. Ten Hagen
  Cell-cell and cell-matrix adhesion are crucial during many stages of eukaryotic development. Here, we provide the first example that mucin-type O-linked glycosylation is involved in a developmentally regulated cell adhesion event in Drosophila melanogaster. Mutations in one member of the evolutionarily conserved family of enzymes that initiates O-linked glycosylation alter epithelial cell adhesion in the Drosophila wing blade. A transposon insertion mutation in pgant3 or RNA interference to pgant3 resulted in blistered wings, a phenotype characteristic of genes involved in integrin-mediated cell interactions. Expression of wild type pgant3 in the mutant background rescued the wing blistering phenotype, whereas expression of another family member (pgant35A) did not, revealing a unique requirement for pgant3. pgant3 mutants displayed reduced O-glycosylation along the basal surface of larval wing imaginal discs, which was restored with wild type pgant3 expression, suggesting that reduced glycosylation of basal proteins is responsible for disruption of adhesion in the adult wing blade. Glycosylation reactions demonstrated that PGANT3 glycosylates certain extracellular matrix (ECM) proteins. Immunoprecipitation experiments revealed that PGANT3 glycosylates tiggrin, an ECM protein known to bind integrin. We propose that this glycosyltransferase is uniquely responsible for glycosylating tiggrin in the wing disc, thus modulating proper cell adhesion through integrin-ECM interactions. This study provides the first evidence for the role of O-glycosylation in a developmentally regulated, integrin-mediated, cell adhesion event and reveals a novel player in wing blade formation during Drosophila development.
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