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Articles by Ligang Tang
Total Records ( 2 ) for Ligang Tang
  Ligang Tang , Wuqing Ouyang , Dongying Yang , Yunjia Liu and Hong Chen
  The goal of this study was to examine the effect of maize plumule extracts on mammary gland tissue and serum hormone levels in SD rats suffering from mammary gland hyperplasia and to investigate the mechanism by which maize plumule extracts inhibit mammary gland hyperplasia. About 56 rats were subcutaneously injected with progesterone combined with estradiol benzoate for the induction of mammary gland hyperplasia and were then randomly divided into 7 groups. Maize plumule extracts were subsequently given to the rats at doses of 0, 1.25, 2.5, 5, 10, 20 and 40 mg kg-1 daily for 20 days. Following treatment, hormone levels in the blood were measured and the morphology of the rat mammary glands was observed by microscopy. Results showed that high doses of maize plumule extracts significantly improved the morphology of lesional tissue and significantly reduced the levels of Follicle-Stimulating Hormone (FSH), serum Estradiol (E2) and Testosterone (T) in the serum and increased the levels of Prolactin (PRL) and serum Luteinizing Hormone (LH). However, the treatment did not have a substantial effect on serum Progesterone (P) levels. It can be concluded that maize plumule extracts containing rich adenine derivatives administered at doses of 2.5-40 mg/kg/day could effectively prevent and treat rat mammary gland hyperplasia.
  Dongying Yang , Chen Gao , Lianqin Zhu , Ligang Tang , Juan Liu and Haisheng Nie
  The chicken (Gallus gallus) is an important model organism in genetics, developmental biology, immunology and evolutionary research. Moreover, besides being an important model organism the chicken is also a very important agricultural species and an important source of food (eggs and meat). The availability of the draft chicken genome sequence provided many possibilities to in detail study a variety of genomic changes during evolution using a comparison between chicken and mammals. For example, compared to mammals, the use of a Z/W sex determination system is a special aspect of the avian genome where the female is the heterogametic sex (ZW) and the male is the homogametic (ZZ) sex. A comparison of the genomic sequences of platypus, chicken and human showed that sex chromosomes evolved separately in birds and mammals.
 
 
 
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