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Articles by L.G. Hassan
Total Records ( 7 ) for L.G. Hassan
  A.N. Ukwuani , M.G. Abukakar , R.A. Shehu and L.G. Hassan
  The pulp extract of Tamarindus indica is used by traditional herbalists as a purgative, drug vehicle and antiobesity agent. The effect of 28 days administration of Tamarindus indica pulp extract on the body weight and lipid profile of the rat was evaluated. There was a significant increase in the weight of the control compared to the treated which significantly decreased (p<0.05) especially the rats given higher doses (2700 to 4500 mg kg-1 body weight). Serum cholesterol and Low Density Lipoprotein (LDL) revealed a significant decrease (p<0.05) while High Density Lipoprotein (HDL) and triglycerides increased in the controlled group compared to the control. Xenical treated group was not significantly different (p<0.05) from the control. Triglycerides significantly increased (p<0.05) and LDL significantly decreased (p<0.05) in the pulp extract treated group as compared to xenical treated group.
  K.J. Umar , L.G. Hassan , S.M. Dangoggo , S.A. Maigandi , N.A. Sani and A.I. Dogonyaro
  Wild leafy vegetables are widely eaten in developing countries and serves as nutrient supplements. The present study examined the effect of feeding albino rats with 75% Melocia corchorifolia leaves with respect to their body weight, liver and kidney biochemical, haematological and histological response. Results showed that the rats fed with M. corchorifolia leaves experience decrease in body weight compared to the control group. The Packed Cell Volume (PCV), haemoglobin concentration (Hb) and Red Blood Cells (RBC), White Blood Cells (WBC), platelets, Mean Carpuscular Volume (MCV), Mean Carpuseular Haemoglobin (MCH), Mean Carpuscular Haemoglobin Concentration (MCHC) and leukocyte (lymphocyte, neutophils, monocytes, eosinophils and basophils) differential counts were not significantly (p>0.05) different between control and treatment. Similarly, serum total protein, globulin and bilirubin were not significantly different, but that of albumin was significantly lower (p<0.05) in the treatment than control group. The serum enzyme activities, i.e., aspartate amino transferase (AST), alanine amino transferase (ALT) and alkaline phosphatase (ALP) were significantly (p<0.05) elevated in sample treatment than the control; which is an indication of organ toxicity by cellular destruction induced by the phyto-toxin present in the fed. Renal function indices-serum creatinine, urea, uric acid and electrolytes were not significantly different (p>0.05) between control and treatment. The results of this study showed that Melocia corchorifolia leaves have a relatively low or no toxicity profile.
  A.U. Itodo , F.W. Abdulrahman , L.G. Hassan , S.A. Maigandi and H.U. Itodo
  Inexpensive remediation method was adopted for Atrazine adsorption by derived Poultry Droppings (PD) and Poultry Wastes (PW) activated carbon. This was proposed to improve the ecological system and add value to the Biomass. GCMS quantitation was employed to investigate the sorption efficiency of the organochlorine herbicide from aqueous phase as it was evidently experimented. Performance of acid catalyzed (PD/A) and Salt treated (PW/Z) sorbents respectively demonstrated about 91.908% and 83.624% atrazine uptake, being highest in their respective series. Both filters however shows a good competitive adsorption though slightly lower than the reference commercial M&B carbon (Comm.) estimated uptake of 23.731 out of 25.00 gdm-3 valued as 94.924% removal. The role played by type of activating agent and physicochemical parameters such as density (0.250-0.496) and high porosity (00.952-0.975) were discussed. The major results support the conclusion that Gas Chromatography as a quantitative instrument is critical for isolating and detecting single equilibrium phase analyte from a multicomponent sample especially when coupled with a mass Spectrophotometer detector and with external standards from same matrix.
  K.J. Umar , L.G. Hassan , H. Usman and R.S.U. Wasagu
  The proximate, minerals and amino acids contents of wild melon (Citrullus ecirrhosus) seeds were determined. The results for proximate analysis (% DW) showed a composition of 3.73±0.25 moisture, 2.12±0.08 ash 26.36±0.10 crude protein, 50.67±0.76 crude lipid, 2.17±0.29 crude fibre, 18.69±0.82 available carbohydrate and energy value of 601.7±8.75 kcal/ 100 g. The seeds amino acids profile revealed that for adults but leucine, lysine and threonine are below the requirement value for children. The overall result implies that seed of the wild melon possessed the potential to be used as a source of nutrition.
  L.G. Hassan and K.J. Umar
  The objective of this study was to assess the nutritive value of Momordica balsamina L. leaves by analysing their proximate composition, amino acid profile and mineral constituents. The results showed that the plant leaves had high moisture content (71.00±0.95% fresh weights). The concentration of estimated crude protein and available carbohydrates on dry weight (DW) basis were 11.29 0.07% and 39.05±2.01% respectively. The leaves also have high ash (18.00±0.56% DW) and crude fibre (29.00±1.23% DW) contents; while crude lipid (2.66±0.13% DW) and energy value (191.16kcal/100g DW) were low. The study detected seventeen amino acids (isoleucine, leucine, lysine, methionine, cysteine, phenylalanine, tyrosine, threonine, valine, alanine, arginine, aspartic acid, glutamic acid, glycine, histidine, proline and serine) with glutamic acid, leucine and aspartic acid being the predominance amino acids. Isoleucine, leucine, valine and aromatic acids were found to be higher than WHO/FAO/UNU (1985) requirement pattern for children, while sulphur containing amino acids are the only limiting amino acids for adults. The results of leaves mineral composition per 100g (DW) were as follows: K (1,320.00mg), Na (122.49mg), Ca (941.00mg), Mg (220.00mg), P (130.46mg), Fe (60.30mg), Cu (5.44mg), Mn (11.60mg) and Zn (3.18mg). Comparing the leaves mineral contents with RDA values, the results indicated that the Momordica balsamina leaves could be good supplement for some mineral elements particularly K, Ca, Mg, Fe, Cu and Mn.
  L.G. Hassan , K.J. Umar , S.M. Dangoggo and A.S. Maigandi
  Plants are the major sources of microelements to populace of the developing world. However, presence of antinutritional factors limit their optimal utilization. In this paper, antinutritional content and their effect on bioavailability of Ca, Fe and Zn in Melocia corchorifolia leaves was investigated. The result indicated that the plant leaves had high level of tannin (4,689.06±2.60 mg/100 g dry weight, DW). The concentration of other antinutritional factors per/100 g DW is as follows: phytate (88.57 mg), total oxalate (585.00 mg), soluble oxalate (217.50 mg), cyanide (16.02 mg) and nitrate (74.41 mg). The predicted Ca, Fe and Zn bioavailability showed that [Oxalate]/[Ca] and [Oxalate]/[(Ca + Mg)] are below the critical level of 2.5 known to impair calcium bioavailability. Furthermore, [Phytate]/[Ca], [Phytate]/[Fe] and [Phytate]/[Zn] are below the critical level of 0.5, 0.4 and 1.5 respectively. However, [Ca][Phytate]/[Zn], 16.72, is above the critical level of 0.5, which indicates significant effect of phytate on Zn bioavailability. From the results it can be concluded that M. corchorifolia leaves could be an important bioresource for Ca and Fe but not for Zn considering the predicted bioavailability.
  A.U. Itodo , F.W. Abdulrahman , L.G. Hassan , F.A. Atiku and H.U. Itodo
  This study was aimed at deriving homemade activated carbon for the rate prediction of liquid phase atrazine uptake. Viable adsorption technique based on sorbate removal by phosphoric acid (H3PO4) Poultry Droppings (PD) was proposed to improve the ecological system. Two ways activation schemes generated activated carbons was applied to herbicide uptake and evaluated with three kinetic models. GC/MS quantitation experiment based on external standard method was performed to demonstrate up to 89.216% atrazine removal. The kinetic equilibrium study showed that a 300 min sorbate-sorbent interaction gave 19.293 out of 25 g dm3 adsorption (being a 77.172% adsorption). This is only 5.140, 1.992, 1.432 and 0.632% higher than the 60, 120, 180 and 240 min interaction with 72.032, 75.180, 75.740 and 76.540% atrazine removal respectively. The pseudo-second order kinetics was observed to be more suitable in predicting the adsorption rate by the sorbate wherein the initial adsorption rate, h was estimated as 0.3646 g/mg/min. A time dependent physisorption phenomenon was evidenced. The major results support the conclusion that the sorted agro-waste has the potential to serve as extractants adsorbents in remediation process.
 
 
 
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