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Articles by L.A. Enye
Total Records ( 2 ) for L.A. Enye
  G.G. Akunna , L.C. Saalu , B. Ogunlade and L.A. Enye
  Various commonly-used products have been reported to contain chemicals that could disrupt estrogen and testosterone hormone. As trade secrets, these chemicals are generally listed as fragrance to mask individual identity. In this study, the reproductive implications of two commonly used perfumes (designated as F1 and F2) in Nigeria were carried out. Sixty adult male wistar rats (12-13 weeks old) were randomly divided into four groups (A-F) of ten rats each. Group A and B rats were exposed to 5 mL kg-1 b.wt. of normal saline for 56 days and 112 days, respectively via whole body inhalation. Group C and D rats were exposed to 5 mL kg-1 b.wt. of a fragrance product designated as F1 for a period of 56 days and 112 days, respectively while Group E and Group F rats were exposed to 5 mL kg-1 b.wt. of a designated fragrance product F2 for a period of 56 days and 112 days, respectively. The results obtained from this study showed a significant (p<0.005) decrease in body weight and absolute testicular weight of the rat models exposed to fragrance when compared to the control groups. It was also observed that the concentration, mobility, livability and morphology of spermatozoa from groups C, D, E and F were significantly lower (p>0.005) when compared to values of the control group A and B. Based on the spermiographic evaluation from this study, fragrance materials could have an adverse effect on spermatozoa of the intact male wistar rats.
  E. Adewole , A. Ojo , T. Oludoro and L.A. Enye
  Background and Objective: The health implications associated with consumption of food crops preserved with pesticides such as diarrhea, food poisons have been a major challenge to health practitioners and the concerned authorities, the objective of the research was to analyze the pesticide residues and compare the contamination rate with Acceptable Dietary Intake (ADI) and Maximum Residue Limit (MRL). Materials and Methods: Phaseolus vulgaris were purchased in two different locations, the samples were powdered using a grinder (Sumeet CM/L 2128945). Fifty grams of powdered flour were soaked in 200 mL of Methanol and the crude extracts were concentrated using a rotary evaporator. The extracts were Characterized using GC-MS and percentage compositions of identified pesticide residues were converted into mg/g as contamination rate and the toxic analysis was done by using the Osiris Online server. Results: In chromatogram A, identified pesticides residue include Dieldrin (96.1 mg g1), Indolizine (67.9 mg g1), permethrin (99.4 mg g1) and compounds identified in chromatogram B include dichlorvos (8.2 mg g1), Diazinon (52.3 mg g1), fenitrothion (17.8 mg g1) and permethrin (122.0 mg g1). These pesticide residues exhibited various toxicological effects, such as; mutagenic, tumorigenic effects. Moreover, the contamination rates of the identified residues were higher than both MRL and ADI. Conclusion: The research work had shown that the two samples had contamination rates higher than both the ADI and MRL, this could pose health hazards to the populace if consumed and it is recommended that the applications of pesticides in foods should be regulated and MRL and ADI should be adhered to.
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