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Articles by L. Feng
Total Records ( 6 ) for L. Feng
  J. LING , L. FENG , Y. LIU , J. JIANG , W.-D. JIANG , K. HU , S.-H. LI and X.-Q. ZHOU
  A 60-day feeding trial was carried out to investigate the effect of iron on growth, body composition and digestive enzyme activities. Diets with seven levels of iron (53.9, 90.0, 115.6, 146.1, 176.0, 215.8 and 266.0 mg iron kg−1 diet) were fed to Jian carp (initial weight 11.4 ± 0.0 g). Per cent weight gain (PWG), feed efficiency (FE) and protein efficiency ratio were the lowest in fish fed the basal diet (P < 0.05). Body protein content was increased with the increasing iron levels (P < 0.05), but moisture, lipid and ash of fish were not significantly affected by dietary iron levels (> 0.05). Activities of trypsin, lipase, α-amylase, Na+, K+-ATPase, alkaline phosphatase and gamma-glutamyl transpeptidase were improved with increasing dietary iron levels. Serum iron were significantly enhanced with dietary iron levels up to 146.1 mg iron kg−1 diet, and plateaued. In conclusion, iron improved digestive enzyme activities of juvenile Jian carp and the dietary iron requirement for serum iron of juvenile Jian carp (11.4–64.0 g) was 147.4 mg iron kg−1 diet with ferrous fumarate as the iron source.
  L. FENG , H.H. HUANG , Y. LIU , J. JIANG , W.D. JIANG , K. HU , S.H. LI and X.Q. ZHOU
  This study was to investigate the effect of dietary thiamin on the immune response and intestinal microflora in juvenile Jian carp (Cyprinus carpio var. Jian). Seven diets (0.25, 0.48, 0.79, 1.06, 1.37, 1.63 and 2.65 mg thiamin kg−1) were fed to Jian carp (8.20 ± 0.02 g). At the end of feeding trial, red blood cell counts and white blood cell counts increased with increasing dietary thiamin levels up to 0.79 and 1.06 mg kg−1 diet, respectively (< 0.05); Lactobacillus counts in intestine increased gradually, and maximum values obtained when the thiamin level was at 0.79 mg kg−1 diet (< 0.05). After the feeding trial, fish were injected with Aeromonas hydrophila only one time on the first day of the challenge trial and fed the same diets as the growth trial for 17 days. The survival rate, leucocyte phagocytic activity, lectin potency, acid phosphatase activity, lysozyme activity, total iron-binding capacity and immunoglobulin M content of fish after being injected with A. hydrophila were all improved with increasing dietary thiamin levels up to a point, respectively (< 0.05). These results suggested that thiamin could improve immune response and the balance of intestinal microflora of juvenile Jian carp.
  L. FENG , W.W. XIAO , Y. LIU , J. JIANG , K. HU , W.D. JIANG , S.H. LI and X.Q. ZHOU
  Oxidative damage and antioxidant status of intestine and hepatopancreas for juvenile Jian carp (Cyprinus carpio var. Jian) fed graded levels of methionine hydroxy analogue (MHA: 0, 5.1, 7.6, 10.2, 12.7, 15.3 g kg−1 diet) for 60 days were studied. Radical scavenging ability, antioxidant enzymes activities such as superoxide dismutase (SOD), catalase (CAT), glutathione-S-transferase (GST), glutathione peroxidase (GPX) and glutathione reducase (GR), as well as glutathione (GSH), protein carbonyl (PC) and malondialdehyde (MDA) contents were assayed in these tissues. Results indicated that anti-superoxide anion capacity in intestine and anti-hydroxyl radical capacity in hepatopancreas significantly improved with dietary MHA levels up to 7.6 and 10.2 g kg−1 diet respectively, whereupon they decreased (< 0.05). SOD, CAT, GST, GPX, GR activities in intestine and hepatopancreas, as well as GSH content in hepatopancreas significantly increased with optimal MHA levels which were in the range of 5.1−10.2 g kg−1 diet, and thereafter decreased (< 0.05). Meanwhile, MDA and PC contents in these tissues together with GOT and GPT activities in plasma significantly decreased with optimal MHA levels which were in the range of 5.1−7.6 g kg−1 diet, and thereafter increased (< 0.05). These results suggested that MHA improved antioxidant status and depressed lipid and protein oxidation in intestine and hepatopancreas.
  N.B. XIE , L. FENG , Y. LIU , J. JIANG , W.D. JIANG , K. HU , S.H. LI and X.Q. ZHOU
  A 9-week feeding trial was carried out with juvenile Jian carp (Cyprinus carpio var. Jian) to study the effects of dietary phosphorus on growth, body composition, intestinal enzyme activities and microflora. Quadruple groups of juvenile Jian carp (7.17 ± 0.01 g) were fed practical diets containing available phosphorus 1.7 (unsupplemented control), 3.6, 5.5, 7.3, 9.2 and 11.0 g kg−1 diet to satiation. Feed intake, specific growth ratio and feed efficiency were the lowest in fish fed the basal diet (< 0.05). Body moisture, protein, lipid content and ash were all significantly affected by dietary available phosphorus levels (< 0.05). Activities of trypsin, amylase, Na+, K+-ATPase, alkaline phosphatase and gamma-glutamyl transpeptidase were improved with increasing dietary phosphorus levels. Intestinal Aeromonas and Escherichia coli decreased with increasing dietary phosphorus up to 3.6 and 5.5 g kg−1 diet respectively (< 0.05), while Lactobacillus increased with the increasing dietary phosphorus up to 9.2 g kg−1 diet (< 0.05). These results suggested that phosphorus could enhance intestinal enzyme activities of juvenile Jian carp and the minimum dietary available phosphorus requirement for SGR of juvenile Jian carp (7.2−63.8 g) was 5.2 g kg−1 diet.
  Q. Wan , F. Wang , Q. Guan , Y. Liu , C. Wang , L. Feng , L. Feng , L. Gao and J. Zhao
  Aims Lipotoxicity has recently been shown to be an important risk factor underlying the pathogenesis of pre-diabetes. However, clinical evidence supporting the treatment of pre-diabetes by improving lipotoxicity is lacking. Here, we conducted an open-label, randomized, controlled trial to investigate whether fenofibrate, the widely used hypolipidaemic agent, might benefit pre-diabetes, with metfomin and diet control, the recommended intervention methods, as positive controls. Methods Newly diagnosed pre-diabetes patients (n = 120) with hypertriglyceridaemia (plasma triglyceride levels between 1.8 and 4.5 mmol/l) were randomly assigned by computer-generated randomization sequence to either control group (no intervention), fenofibrate group (200 mg once a day), metformin group (500 mg three times a day) or diet-controlled group (diet recommendation). Plasma biochemistry examination was performed every 2 months. The primary endpoint was the outcome of the natural course of pre-diabetes, evaluated by oral glucose tolerance test after 6-month follow-up. Results Twenty subjects in the fenofibrate group, 24 subjects in the metformin group and 25 subjects in both the diet-controlled group and the control group finished the trial. Fenofibrate, metformin and diet control had protective effects on hypertriglyceridaemic pre-diabetes, evidenced by 53.3, 70 and 30% participants regressed to normoglycaemia, respectively. The effects of fenofibrate and metformin were comparable (P > 0.05), while diet control was less effective (P < 0.05). Liver damage occurred in six subjects in the fenofibrate group and gastrointestinal symptoms occurred in four subjects in the metformin group. No serious adverse events occurred. Conclusion Controlling lipotoxicity by fenofibrate could effectively ameliorate the natural course of hypertriglyceridaemic pre-diabetes.
  B. Jin , L. Feng , H.J. Piao and Z.Q. Diao
  Most of the present patent retrieval systems only use a single retrieval engine and cannot meet the growing demand of patent uses. Fusion of the results set of various retrieval engines is one of the best solutions for patent retrieval. In this study, we propose a Result Set Relevance Inference (RSRI) model for patent retrieval fusion. It makes use of two result sets returned from keyword retrieval and semantic retrieval engine and then fuses them to a new result set after calculation as per their weights. Using an experimental data set, results showed that the RSRI model can improve the recall and mean average precision in most cases.
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