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Articles by Kyari Abba Sanda
Total Records ( 3 ) for Kyari Abba Sanda
  Mohammed Shaibu Auwal , Abdulnasir Tijjani , Fatima Abba Lawan , Ismail Alhaji Mairiga , Amina Ibrahim , Abdulhamid Baba Njobdi , Abdullahi Shuaibu , Kyari Abba Sanda , Abubakar Muhammad Wakil and Ahmad Bello Thaluvwa
  The quantitative Phytochemistry and hypoglycaemic properties of crude mesocarp extract of Hyphaene thebaica (doumpalm) on normoglycemic wistar albino rats were investigated. Fresh mesocarp of Hyphaene thebaica was bought in September 2012 from Gamboru market, Borno State, North eastern, Nigeria. One hundred and 50 g of aqueous product were prepared by reflux method from three hundred and 50 g of initial powdered sample. Phytochemical screening for biochemical and elemental contents were conducted. The quantitative phytochemical screening revealed the presence of low level of tannins, steroids and moderate level of saponins, carbohydrates, cardiac glycosides, flavonoids, terpenes and terpinoids. Elemental analysis of the extract revealed the presence of calcium, magnesium, potassium, iron and sodium in moderate concentration, manganese, zinc and silicon is low, whereas the amount of nickel, cobalt, molybdenum, arsenic and lead are negligible. Administration of crude mesocarp extract of Hyphaene thebaica in normoglycemic rats at the dosage of 400, 600 and 800 mg kg-1 for four weeks significantly (p<0.05) reduced blood glucose level of the rats at 3-4 weeks post administration. This finding validates the traditional application of Hyphaene thebaica crude mesocarp extract in the management of Diabetes mellitus in Borno State, Nigeria.
  Mohammed Shaibu Auwal , Abdullahi Shuaibu , Fatima Adamu Lawan , Kyari Abba Sanda , Abdulhamid Baba Njobdi , Amina Ibrahim , Isa Adamu Gulani , Bitrus Wampana , Giwa I. Lateefat and Yagana Kibon
  The effect of crude mesocarp extract of Hyphaene thebaica on white blood cell and differential leucocytic counts in wistar albino rats was evaluated. Fresh mesocarp of Hyphaene thebaica collected were ground into fine powder, extracted by reflux method and subjected to phytochemical screening for biochemical principles. The quantitative phytochemical screening revealed the presence of low level of tannins, steroids and moderate level of saponins, carbohydrates, cardiac glycosides, flavonoids, Terpenes and Terpinoids. The elemental analysis of the extract revealed the presence of calcium, magnesium, potassium, iron and sodium in moderate concentration. The amount of zinc and silicon were low whereas, nickel, cobalt, molybdenum, arsenic and lead were negligible. The crude mesocarp extract administered at the dosages of 400, 600 and 800 mg kg-1 significantly (p<0.05) increased cells count of Lymphocytes, Monocytes, Eosinophils and Basophils during four weeks of administration. The extract did not have any significant effect on Neutrophils count throughout the period of treatment. This finding validates the folkloric application of the mesocarp extract of Hyphaene thebaica in the management of parasitic and viral infections in North eastern region of Nigeria.
  Mohammed Shaibu Auwal , Sanni Saka , Abdullahi Shuaibu , Ismail Alhaji Mairiga , Kyari Abba Sanda , Amina Ibrahim , Fatima Abba Lawan , Ahmad Bello Thaluvwa and Abdulhamid Baba Njobdi
  The phytochemical properties and hypoglycemic activity of the aqueous and fractionated portions of Acacia nilotica (Thorn mimosa) pod extracts on blood glucose level in wistar albino rats was studied. The result of the phytochemical analysis of the aqueous extract of Acacia nilotica pod revealed that tannins, saponins, flavonoids, carbohydrate and glycosides are present, while anthraquinones, alkaloids, terpene and steroids were absent, the fractionated pod extracts showed moderate carbohydrates, tannins, saponins, cardiac glycosides and flavonoids in ethyl acetate fraction and low amounts in N-butanol fraction. The residue fraction has all the phytochemicals mentioned in the fractionated portions except flavonoids that are absent. There was significant (p<0.05) decrease in blood glucose level in the rats treated with 400-800 mg kg-1 of aqueous extract and 800 mg kg-1 of Ethyl-acetate and N-butanol fractionated 12-18 h post extract administration, respectively.
 
 
 
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