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Articles by Kudrat-e-zahan
Total Records ( 3 ) for Kudrat-e-zahan
  M. Shamim Hossain , M. Aslam Hossain , R. Islam , A. H. M. Khurshid Alam , Kudrat-e-Zahan , S. Sarkar and M. Akhter Farooque
  Owing to the biological importance of metalloelements in many biological processes, especially metabolic processes, magnesium(II) complexes were synthesized and examined for their antimicrobial and cytotoxic activities. Among the two synthesized organometalic complexes [Mg(2-ap)2, A] and [Mg(2-ab)2, C], the maximum antibacterial and antifungal activities were shown by the compound A. Among the ligands, 2-aminophenol (B) showed more antibacterial activity than 2-aminobenzoic acid (D). The minimum inhibitory concentration for the complex A against five pathogenic bacteria Streptococcus-haemolyticus, Bacillus subtilis, Staphylococcus aureus, Salmonella typhi and Escherichia coli were found in the range of 32-64 μg ml-1. The complexes were also tested for their cytotoxicity using brine shrimp lethality bioassay method and the LC50 values of the complexes A and C were found to be 5.7 and 24.3 µg ml-1 respectively. Antibacterial, antifungal and cytotoxic studies undertaken for the above compounds indicated structure-activity relationships. These metalloderivatives were more active than the parent compounds (ligands).
  M. Ashraful Alam , Kudrat-e-zahan , M. Shamim Hossain and Fahmida Zerin Seema
  Three new cobalt μ-peroxo complexes [Co(2-apy)(O2)(OX), C1], [Co(2-apy)(O2)(2-ap), C2] and [Co(2-apy)(O2)(2-ab), C3] and two new zirconium μ-peroxo complexes [Zr(2-na)(O2)(OX), C5] and [Zr(2-ap)(O2)(OX), C5] were tested for their antibacterial activity by disc diffusion and serial dilution methods. All the coordination complexes were active against various test pathogenic organisms. The minimum inhibitory concentration (MIC) of the complexes was estimated between 32-64 μg ml-1 against Bacillus subtilis and Escharicha coli. The cytotoxicity of the five newly synthesized complexes was screened using brine shrimp lethality bioassay method and the LC50 values were calculated using probit analysis. LC50 values of the complexes C1-C5 were found 14.15, 9.12, 14.15, 29.51 and 5.75 7μg ml-1, respectively.
  M. Shamim Hossain , Kudrat-e-zahan , M. Anwar-ul-Islam , S. Sarkar , Jahanara Nassin , Aktarul Islam , M. Akhter Farooque and M. Asraful Alam
  Three coordination complexes of metals with mixed ligands [Mn(ED)(2-ap)2, A], [Fe(ED)(2-ab)2, B] and [Fe(ED)(2-ap)2, C] were tested for their antimicrobial activity by disc diffusion and serial dilution methods. All the complexes were active against various test pathogenic organisms. The maximum antibacterial and antifungal activities were shown by the manganese complex A. The minimum inhibitory concentration of the complex A was determined against four pathogenic bacteria Bacillus subtilis, Streptococcus-β-haemolyticus,Escherichia coli and Salmonella typhi and values were found between 16-32 μg ml-1. The manganese complex A also showed potent cytotoxic effect which is indicative of its probable effect on cancer cell lines.
 
 
 
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