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Articles by Kang Sun
Total Records ( 2 ) for Kang Sun
  Fan Yang , Xiao Ling Zhang , Kang Sun , Mo Jun Xiong , Ping Fang Xia , Zi Jian Cao and Zi Jian Cao
  A facile approach for synthesis of the triarylamine-endcapped X-branched oligofluorene, X-OF(2)Ph-NPh and its corresponding linear oligofluorene, OF(2)Ph-NPh by Suzuki cross-coupling as a key reaction has been developed. This novel X-branched oligofluorene exhibits much higher thermal and electrochemical stabilities and enhanced electroluminescent properties as comparison to its corresponding linear counterpart. Using a simple two-layer OLED structure of ITO/oligofluorene (40 nm)/PBD (40 nm)/LiF (1 nm)/Al (150 nm), the luminance efficiency of X-OF(2)Ph-NPh-based OLED can also reach up to 2.8 cd/A with a maximum brightness of 1700 cd/m2 and remarkably better than 1.2 cd/A with a maximum brightness of 700 cd/m2 for its corresponding linear oligofluorene OF(2)Ph-NPh-based OLEDs.
  Leslie Myatt and Kang Sun
  The fetal membranes fulfill several functions during pregnancy. In addition to containing the products of conception and amniotic fluid, they presumably have barrier functions and fulfill paracrine signaling functions between the maternal (decidual) and fetal compartments. As the membranes are in an ideal place to receive both maternal and fetal signals and transmit signals to uterine myometrium, there has been a specific focus on the role of membranes in the initiation and maintenance of parturition. In this review, we summarize the data obtained in our laboratories as well as the data reported in the literature particularly with regard to the synthesis of steroids and prostaglandins in the fetal membranes, in signaling fetal maturation and in parturition. The fetal membranes are a major site both of prostaglandin synthesis and of prostaglandin metabolism. In addition, the abundant expression of 11beta-hydroxysteroid dehydrogenase 1 (11β-HSD1), which converts biologically inactive cortisone into active cortisol, in the fetal membranes may provide an extra-adrenal source of glucocorticoids for the fetal compartment during gestation. Accumulating evidence indicates that a positive feedback loop involving glucocorticoids, proinflammatory cytokines, prostaglandins, surfactant protein-A (SP-A) and 11β-HSD1 is formed locally in human fetal membranes towards term or in preterm labor. This positive feedback loop would produce abundant biologically active glucocorticoids and prostaglandins in the fetal membranes or amniotic fluid, which would ultimately promote fetal organ maturation and initiate parturition.
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