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Articles by Kai Li
Total Records ( 6 ) for Kai Li
  Kai Li and Shan-lin Yang
  We consider a class of non-identical parallel-machine scheduling problems in which the goal is to minimize total (or mean) weighted (or unweighted) completion time. Models and relaxations are collected and classified in this paper. Heuristics and optimizing techniques are surveyed for the problems. And a few of interesting areas for future research are also provided.
  Guodong Li , Pengfei Jin and Kai Li
  The existence of time-varying network delay will have some negative impacts on some network services. The dynamic changes of network delay reflect the load characteristics of network path. An important basis for the implementation of congestion control and routing is the accurate prediction of network delay. In this paper, a delay prediction model based on Radial Basis Function (RBF) neural network is establishe which is trained by APC-III algorithm and the method of least squares. This model avoids the cumbersome process of model structure identification and model checking in traditional time-series analysis and overcomes the shortcoming that the traditional neural network can easily fall into local extremum and overtraining. The simulation results show that this model can predict network delay with high accuracy.
  Kai Li , Xiuting Wei , Zhenxian Wei and Leian Zhang
  According to the nonlinear and strong coupling characteristics of water-injecting process of large displacement and high pressure reciprocating pumps, the system for monitoring water injection with constant pressure was constructed and then the fuzzy rules for constant pressure control was obtained through site test. Furthermore, fuzzy Proportion Integration Differentiation (PID) gain conditioner (FPGC) control algorithm was put forward, with the error and its changing rate of outlet total pressure of injection station as input variables. Finally, the water-injecting experiments using conventional PID control algorithm and FPGC control algorithm were carried out respectively. Practical application proved that the former algorithm can ensure the outlet main pressure error (less than 0.1 MPa) and depress the system oscillation, with its feasibility applied to injection station of large displacement and high pressure reciprocating pump verified.
  Jingqun Gao , Dan Li , Jun Wang , Xudong Jin , Tong Wu , Kai Li , Pingli Kang and Xiangdong zhang
  Two lanthanide complexes, (enH2)[SmIII(egta)(H2O)]2 • 6H2O (1) (en = ethylenediamine and H4egta = ethyleneglycol−bis−(2−aminoethylether)−N,N,N′,N′−tetraacetic acid) and (enH2)1.5[SmIII(ttha)] • 4.5H2O (2) (H6ttha = triethylenetetramine−N,N,N′,N″,N′″,N′″−hexaacetic acid), have been synthesized and characterized by IR spectroscopy, thermal analysis, and single-crystal X−ray diffraction. The (enH2)[SmIII(egta)(H2O)]2 • 6H2O is mononuclear nine−coordinate and crystallizes in the monoclinic crystal space group P21/n with the cell dimensions a = 13.0563(13) Å, b = 12.6895(11) Å, c = 14.9497(15) Å, β = 105.782(2)°. The polymeric (enH2)1.5[SmIII(ttha)] • 4.5H2O is also nine−coordinate crystallizing in the monoclinic crystal space group P21/n, but with cell dimensions a = 17.7800(16) Å, b = 9.7035(10) Å, c = 22.096(2) Å, β = 118.8740(10)°. Each ethylenediammonium (en ) cation in (enH2)[SmIII(egta)(H2O)]2 • 6H2O connects three adjacent [SmIII(egta)(H2O)] anions through hydrogen bonds, while in (enH2)1.5[SmIII(ttha)] • 4.5H2O, there are two types of en cations, which form hydrogen bonds with the neighboring [SmIII(ttha)]3− anions, leading to the formation of a 2−D ladder-like layer structure.
  Jingqun Gao , Dan Li , Jun Wang , Xudong Jin , Pingli Kang , Tong Wu , Kai Li and Xiangdong Zhang
  A 2-D binuclear coordination polymer, {[YIII(Hpdta)(H2O)]2 ·6H2O} n (H4pdta = propylenediamine-N,N,N′,N′-tetraacetic acid), has been synthesized through direct hydrothermal reaction and characterized by infrared spectrum and thermal analysis. Single-crystal X-ray diffraction reveals that Y(III) is eight-coordinate of almost standard square antiprismatic polyhedron.
  Kai Li , Alex Casta , Rui Wang , Enerlyn Lozada , Wei Fan , Susan Kane , Qingyuan Ge , Wei Gu , David Orren and Jianyuan Luo
  Werner syndrome is an autosomal recessive disorder associated with premature aging and cancer predisposition caused by mutations of the WRN gene. WRN is a member of the RecQ DNA helicase family with functions in maintaining genome stability. Sir2, an NAD-dependent histone deacetylase, has been proven to extend life span in yeast and Caenorhabditis elegans. Mammalian Sir2 (SIRT1) has also been found to regulate premature cellular senescence induced by the tumor suppressors PML and p53. SIRT1 plays an important role in cell survival promoted by calorie restriction. Here we show that SIRT1 interacts with WRN both in vitro and in vivo; this interaction is enhanced after DNA damage. WRN can be acetylated by acetyltransferase CBP/p300, and SIRT1 can deacetylate WRN both in vitro and in vivo. WRN acetylation decreases its helicase and exonuclease activities, and SIRT1 can reverse this effect. WRN acetylation alters its nuclear distribution. Down-regulation of SIRT1 reduces WRN translocation from nucleoplasm to nucleoli after DNA damage. These results suggest that SIRT1 regulates WRN-mediated cellular responses to DNA damage through deacetylation of WRN.
 
 
 
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